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nucleophilic reagent

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (13) Drug Intermediate (1)
By Research Areas:	Infection (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-79444

Bis(pinacolato)diborane	Biochemical Assay Reagents	Others
Bis(pinacolato)diborane is an organoboron reagent. Bis(pinacolato)diborane serves as a source of the [Bpin] moiety with pronounced nucleophilic character and is used in the synthesis of various organoboranes, including organoboron compounds and arylboronates .Bis(pinacolato)diborane reacts with p-benzyne to produce tetraborylated products through a series of steps involving addition and 1,2-migration of the boryl group .

HY-79647

Fmoc-OSu N-(Fmoc-oxy)succinimide	Biochemical Assay Reagents	Others
Fmoc-OSu (N-(Fmoc-oxy)succinimide) is an acylating agent that targets amino groups (-NH2). It can selectively protect the amino groups of amino acids by covalently binding with primary or secondary amines through nucleophilic substitution reactions. Fmoc-OSu forms a stable amide bond with the amino group to avoid side reactions of the amino group in peptide synthesis. It can also be used as a fluorescent labeling reagent to react with glycosylamines for efficient labeling of N-sugar chains. Fmoc-OSu can be used as an Fmoc protection strategy in peptide synthesis, and as a fluorescent labeling and analysis method for N-sugar chains .

HY-Y0971

Tetrabutylammonium fluoride (solution),1M in THF TBAF	Biochemical Assay Reagents	Others
Tetrabutylammonium fluoride is an organic compound containing both ammonium and fluorine functional groups. It is commonly used as a reagent in various chemical synthesis applications, especially as a source of fluoride ions for nucleophilic reactions. Tetrabutylammonium fluoride has several properties that make it suitable for these applications, including its high solubility in polar solvents and its ability to selectively activate certain chemical bonds. In addition, it can be used as a catalyst for organic reactions and as an electrolyte for batteries.

HY-Y0232

Meldrum's acid 2,2-Dimethyl-1,3-dioxane-4,6-dione	Biochemical Assay Reagents	Others
Meldrum's acid (2,2-Dimethyl-1,3-dioxane-4,6-dione) is a nucleophilic reagent. Meldrum's acid participates in Michael addition reactions. Meldrum's acid can be used in asymmetric organocatalysis .

HY-D0980

Biotin-DADOO Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin	Biochemical Assay Reagents	Infection
Biotin-DADOO (Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin) is a biotin-containing amine compound and a biotinylation reagent. As an amino component, Biotin-DADOO participates in the nucleophilic ring-opening reaction of epoxidized ω-double bonds during the synthesis of biotinylated inhibitor derivatives. Biotin-DADOO can be conjugated with carboxymethyl cellulose derivatives. Biotin-DADOO is involved in the synthesis of biotin-estradiol conjugates for enzyme immunoassays. Biotin-DADOO can be used in the research of influenza A .

HY-137541

2-Nitro-5-thiocyanatobenzoic acid NTCB	Biochemical Assay Reagents	Others
2-Nitro-5-thiocyanatobenzoic acid (NTCB) is a highly reactive reagent that transfers its cyano group rapidly to a nucleophilic thiolate. 2-Nitro-5-thiocyanatobenzoic acid has been proposed as a reagent for converting thiol groups in proteins into their S-cyano derivatives .

HY-W042557

Tetrabutylammonium trifluoromethanesulfonate	Biochemical Assay Reagents	Others
Tetrabutylammonium trifluoromethanesulfonate, commonly known as TBAOTf. TBAOTf is widely used as a strong acid catalyst and phase transfer agent in organic synthesis, especially for reactions involving nucleophilic substitution, elimination, and rearrangement, in addition, it is also used as an electrolyte additive for rechargeable batteries and a stabilizer of supercritical fluids Due to its high stability, solubility and selectivity, TBAOTf is considered to be a highly efficient and multifunctional reagent in various applications.

HY-125372

2-Amino benzamidoxime ABAO	Biochemical Assay Reagents	Others
2-Amino benzamidoxime (ABAO) acts as a bioconjugation reagent precursor and a fluorescent probe precursor. 2-Amino benzamidoxime contains an aniline group for imine activation of aldehydes, as well as a nucleophilic group (Nu:) located at the ortho position of the amine, which is responsible for intramolecular cyclization. 2-Amino benzamidoxime reacts with glyoxal at the N-terminus of phage-displayed peptide libraries. Derivatives of 2-Amino benzamidoxime can be used for protein bioconjugation. Derivatives of 2-Amino benzamidoxime serve as fluorescent probes .\n

HY-W011985

H-Arg-NH2 hydrochloride	Biochemical Assay Reagents	Others
H-Arg-NH2 hydrochloride is a nucleophilic reagent. H-Arg-NH2 hydrochloride can be used in experiments related to the detection of enzyme activity centers .

HY-W025838

4,5-Dimethylbenzene-1,2-diamine	Drug Intermediate	Others
4,5-Dimethylbenzene-1,2-diamine is a substitute for aromatic diamine compound. 4,5-Dimethylbenzene-1,2-diamine act as a bidentate nucleophilic reagent and participates in the palladium (II)-mediated isocyanate addition reaction to construct a diaminocarbene palladium complex with potential catalytic activity .

HY-W095635

Tetramethylammonium fluoride tetrahydrate	Biochemical Assay Reagents	Others
Tetramethylammonium fluoride tetrahydrate (TMAF) is a quaternary ammonium salt. TMAF is commonly used as a weak base and a source of fluoride ions in various organic reactions, including nucleophilic substitution, functional group deprotection, and ring-opening polymerization. Unlike other fluoride sources, TMAF is compatible with many functional groups, making it a versatile tool in synthetic chemistry. Functional reagents, In addition, TMAF has been used as a fluorinating agent in medicinal chemistry, for the preparation of radiotracers and protein modification in biochemistry, and the tetrahydrate form of TMAF is more stable and easier to handle than the anhydrous form.

HY-34469

2-Cyanophenylboronic acid	Biochemical Assay Reagents	Others
2-Cyanophenylboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 2-Cyanophenylboronic acid contains both nucleophilic and electrophilic centres. 2-Cyanophenylboronic acid can function as an efficient electrolyte additive for high voltage LCO cathode. 2-Cyanophenylboronic acid enhances the structural reversibililty and decreases the hydrofluoric acid formation .

HY-130893A

Biotin-EDA TFA	Biochemical Assay Reagents	Others
Biotin-EDA TFA is a nucleophilic biotinylation reagent used for the conjugation of various substrates and identification and quantification using biotin-conjugated fluorescent labels .

HY-W129533

tert-Butyl 1H-indol-4-ylcarbamate	Biochemical Assay Reagents	Others
tert-Butyl 1H-indol-4-ylcarbamate is a nucleophilic reagent. tert-Butyl 1H-indol-4-ylcarbamate induces the formation of the stable triple hydrogen-bonded complex A-TS-Re. tert-Butyl 1H-indol-4-ylcarbamate undergoes Friedel-Crafts reactions with β,γ-unsaturated α-ketiminoesters .

Cat. No.	Product Name	Type

HY-79444

Bis(pinacolato)diborane	Biochemical Assay Reagents
Bis(pinacolato)diborane is an organoboron reagent. Bis(pinacolato)diborane serves as a source of the [Bpin] moiety with pronounced nucleophilic character and is used in the synthesis of various organoboranes, including organoboron compounds and arylboronates .Bis(pinacolato)diborane reacts with p-benzyne to produce tetraborylated products through a series of steps involving addition and 1,2-migration of the boryl group .

Bis(pinacolato)diborane

Biochemical Assay Reagents

Bis(pinacolato)diborane is an organoboron reagent. Bis(pinacolato)diborane serves as a source of the [Bpin] moiety with pronounced nucleophilic character and is used in the synthesis of various organoboranes, including organoboron compounds and arylboronates .Bis(pinacolato)diborane reacts with p-benzyne to produce tetraborylated products through a series of steps involving addition and 1,2-migration of the boryl group .

HY-79647

Fmoc-OSu N-(Fmoc-oxy)succinimide	Biochemical Assay Reagents
Fmoc-OSu (N-(Fmoc-oxy)succinimide) is an acylating agent that targets amino groups (-NH2). It can selectively protect the amino groups of amino acids by covalently binding with primary or secondary amines through nucleophilic substitution reactions. Fmoc-OSu forms a stable amide bond with the amino group to avoid side reactions of the amino group in peptide synthesis. It can also be used as a fluorescent labeling reagent to react with glycosylamines for efficient labeling of N-sugar chains. Fmoc-OSu can be used as an Fmoc protection strategy in peptide synthesis, and as a fluorescent labeling and analysis method for N-sugar chains .

Fmoc-OSu

N-(Fmoc-oxy)succinimide

Biochemical Assay Reagents

Fmoc-OSu (N-(Fmoc-oxy)succinimide) is an acylating agent that targets amino groups (-NH2). It can selectively protect the amino groups of amino acids by covalently binding with primary or secondary amines through nucleophilic substitution reactions. Fmoc-OSu forms a stable amide bond with the amino group to avoid side reactions of the amino group in peptide synthesis. It can also be used as a fluorescent labeling reagent to react with glycosylamines for efficient labeling of N-sugar chains. Fmoc-OSu can be used as an Fmoc protection strategy in peptide synthesis, and as a fluorescent labeling and analysis method for N-sugar chains .

HY-Y0971

Tetrabutylammonium fluoride (solution),1M in THF TBAF	Biochemical Assay Reagents
Tetrabutylammonium fluoride is an organic compound containing both ammonium and fluorine functional groups. It is commonly used as a reagent in various chemical synthesis applications, especially as a source of fluoride ions for nucleophilic reactions. Tetrabutylammonium fluoride has several properties that make it suitable for these applications, including its high solubility in polar solvents and its ability to selectively activate certain chemical bonds. In addition, it can be used as a catalyst for organic reactions and as an electrolyte for batteries.

Tetrabutylammonium fluoride (solution),1M in THF

TBAF

Biochemical Assay Reagents

Tetrabutylammonium fluoride is an organic compound containing both ammonium and fluorine functional groups. It is commonly used as a reagent in various chemical synthesis applications, especially as a source of fluoride ions for nucleophilic reactions. Tetrabutylammonium fluoride has several properties that make it suitable for these applications, including its high solubility in polar solvents and its ability to selectively activate certain chemical bonds. In addition, it can be used as a catalyst for organic reactions and as an electrolyte for batteries.

HY-Y0232

Meldrum's acid 2,2-Dimethyl-1,3-dioxane-4,6-dione	Biochemical Assay Reagents
Meldrum's acid (2,2-Dimethyl-1,3-dioxane-4,6-dione) is a nucleophilic reagent. Meldrum's acid participates in Michael addition reactions. Meldrum's acid can be used in asymmetric organocatalysis .

HY-D0980

Biotin-DADOO Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin	Biochemical Assay Reagents
Biotin-DADOO (Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin) is a biotin-containing amine compound and a biotinylation reagent. As an amino component, Biotin-DADOO participates in the nucleophilic ring-opening reaction of epoxidized ω-double bonds during the synthesis of biotinylated inhibitor derivatives. Biotin-DADOO can be conjugated with carboxymethyl cellulose derivatives. Biotin-DADOO is involved in the synthesis of biotin-estradiol conjugates for enzyme immunoassays. Biotin-DADOO can be used in the research of influenza A .

Biotin-DADOO

Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin

Biochemical Assay Reagents

Biotin-DADOO (Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin) is a biotin-containing amine compound and a biotinylation reagent. As an amino component, Biotin-DADOO participates in the nucleophilic ring-opening reaction of epoxidized ω-double bonds during the synthesis of biotinylated inhibitor derivatives. Biotin-DADOO can be conjugated with carboxymethyl cellulose derivatives. Biotin-DADOO is involved in the synthesis of biotin-estradiol conjugates for enzyme immunoassays. Biotin-DADOO can be used in the research of influenza A .

HY-W042557

Tetrabutylammonium trifluoromethanesulfonate	Biochemical Assay Reagents
Tetrabutylammonium trifluoromethanesulfonate, commonly known as TBAOTf. TBAOTf is widely used as a strong acid catalyst and phase transfer agent in organic synthesis, especially for reactions involving nucleophilic substitution, elimination, and rearrangement, in addition, it is also used as an electrolyte additive for rechargeable batteries and a stabilizer of supercritical fluids Due to its high stability, solubility and selectivity, TBAOTf is considered to be a highly efficient and multifunctional reagent in various applications.

Tetrabutylammonium trifluoromethanesulfonate

Biochemical Assay Reagents

Tetrabutylammonium trifluoromethanesulfonate, commonly known as TBAOTf. TBAOTf is widely used as a strong acid catalyst and phase transfer agent in organic synthesis, especially for reactions involving nucleophilic substitution, elimination, and rearrangement, in addition, it is also used as an electrolyte additive for rechargeable batteries and a stabilizer of supercritical fluids Due to its high stability, solubility and selectivity, TBAOTf is considered to be a highly efficient and multifunctional reagent in various applications.

HY-W095635

Tetramethylammonium fluoride tetrahydrate	Biochemical Assay Reagents
Tetramethylammonium fluoride tetrahydrate (TMAF) is a quaternary ammonium salt. TMAF is commonly used as a weak base and a source of fluoride ions in various organic reactions, including nucleophilic substitution, functional group deprotection, and ring-opening polymerization. Unlike other fluoride sources, TMAF is compatible with many functional groups, making it a versatile tool in synthetic chemistry. Functional reagents, In addition, TMAF has been used as a fluorinating agent in medicinal chemistry, for the preparation of radiotracers and protein modification in biochemistry, and the tetrahydrate form of TMAF is more stable and easier to handle than the anhydrous form.

Tetramethylammonium fluoride tetrahydrate

Biochemical Assay Reagents

Tetramethylammonium fluoride tetrahydrate (TMAF) is a quaternary ammonium salt. TMAF is commonly used as a weak base and a source of fluoride ions in various organic reactions, including nucleophilic substitution, functional group deprotection, and ring-opening polymerization. Unlike other fluoride sources, TMAF is compatible with many functional groups, making it a versatile tool in synthetic chemistry. Functional reagents, In addition, TMAF has been used as a fluorinating agent in medicinal chemistry, for the preparation of radiotracers and protein modification in biochemistry, and the tetrahydrate form of TMAF is more stable and easier to handle than the anhydrous form.

HY-34469

2-Cyanophenylboronic acid	Biochemical Assay Reagents
2-Cyanophenylboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 2-Cyanophenylboronic acid contains both nucleophilic and electrophilic centres. 2-Cyanophenylboronic acid can function as an efficient electrolyte additive for high voltage LCO cathode. 2-Cyanophenylboronic acid enhances the structural reversibililty and decreases the hydrofluoric acid formation .

2-Cyanophenylboronic acid

Biochemical Assay Reagents

2-Cyanophenylboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 2-Cyanophenylboronic acid contains both nucleophilic and electrophilic centres. 2-Cyanophenylboronic acid can function as an efficient electrolyte additive for high voltage LCO cathode. 2-Cyanophenylboronic acid enhances the structural reversibililty and decreases the hydrofluoric acid formation .

HY-130893A

Biotin-EDA TFA	Biochemical Assay Reagents
Biotin-EDA TFA is a nucleophilic biotinylation reagent used for the conjugation of various substrates and identification and quantification using biotin-conjugated fluorescent labels .

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