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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
62 Results for "
nucleoside phosphoramidite
" in MedChemExpress (MCE) Product Catalog:
Products (62)
62 Results for "nucleoside phosphoramidite" in MCE Product Catalog:
Research Areas:
5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) is a nucleoside phosphoramidite monomer used to synthesize locked nucleic acid (LNA) analog oligonucleotides. It can be used as a building block of antisense oligonucleotides (ASOs) to target complementary RNA sequences. 5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) locks the furanose ring into an N-type conformation through 2',4'-constrained ethyl (cEt) modification, enhancing hybridization affinity and mismatch discrimination with RNA, while significantly improving the resistance of oligonucleotides to exonuclease digestion. 5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) mediates RNase H-dependent mRNA degradation or inhibits translation by forming a stable hybrid with RNA, thereby achieving gene expression regulation. 5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) is mainly used in the development of antisense drugs, gene function research and oligonucleotide synthesis related to disease treatment .
Cat. No.: HY-45409
CAS No.: 146954-75-8
Synonyms: 2'-F-dU phosphoramidite
Research Areas:
DMT-2’ Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) is a uridine phosphoramidite with a fluorine in the 2’ position. DMT-2’ Fluoro-dU Phosphoramidite could be used for nucleoside modification and synthesis of DNA .
Cat. No.: HY-W006102
CAS No.: 104992-55-4
Synonyms: DMT-2'O-TBDMS-rA(bz) phosphoramidite
Research Areas:
Bz-rA Phosphoramidite (DMT-2'O-TBDMS-rA(bz) Phosphoramidite) a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with Benzoyl (Bz) base protection, for use in oligonucleotide synthesis .
Research Areas:
DMT-2'O-MOE-rG(ib) Phosphoramidite belongs to cyanoethyl-protected nucleoside phosphoramidites. DMT-2'O-MOE-rG(ib) Phosphoramidite is a derivative of nucleotide and guanosine. DMT-2'O-MOE-rG(ib) Phosphoramidite can be used for the stereochemical synthesis of phosphorothioate oligonucleotides .
Cat. No.: HY-45492
CAS No.: 144089-97-4
Synonyms: 2'-F-ibu-dG phosphoramidite
Research Areas:
DMT-2'Fluoro-DG(IB) Amidite (2'-F-ibu-dG Phosphoramidite) is a nucleoside that can be employed for oligonucleotide synthesis. DMT-2'Fluoro-DG(IB) Amidite can be used to prepare 4'-modified 2'-deoxy-2'-fluorouridine .
Research Areas:
DMT-2'-O-MOE-rA(Bz) phosphoramidite is an adenine nucleoside analog. DMT-2'-O-MOE-rA(Bz) phosphoramidite can be used in research on oligonucleotide synthesis .
Cat. No.: HY-D1090
CAS No.: 82855-40-1
Research Areas:
DMTr-LNA-5MeU-3-CED-phosphoramidite is a Phosphoramidite derivative and Nucleoside derivative .
Cat. No.: HY-154481
CAS No.: 179479-03-9
Research Areas:
3’-O-Me-C(Bz)-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
Cat. No.: HY-W141394
CAS No.: 85079-00-1
Synonyms: N-Benzoyl-2′-O-methyladenosine
Research Areas:
Bz-OMe-rA (N-Benzoyl-2′-O-methyladenosine) is a nucleoside analog with an N-benzoyl protecting group and a 2'-O-methyladenosine phosphoramidite unit. Bz-OMe-rA serves as a starting material for the chemical synthesis of the 5'-terminal cap structure of cytoplasmic polyhedrosis virus mRNA and also acts as a building block for solid-phase RNA oligonucleotide synthesis .
Cat. No.: HY-W570891
CAS No.: 206055-78-9
Research Areas:
DMTr-LNA-C(Bz)-3-CED-phosphoramidite is a purine nucleoside analog that can be used to synthesize oligonucleotides .
Target:
Research Areas:
2'-O-MOE-5MeU-3'-phosphoramidite is a phosphoramidite derivative that can be used for oligonucleotide synthesis .
Cat. No.: HY-49200
CAS No.: 182495-83-6
Research Areas:
DMT-2'-F-dC(Bz)-CE-Phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
Cat. No.: HY-154602
CAS No.: 157327-97-4
Research Areas:
2’-dG (iBu)-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
Cat. No.: HY-154599
CAS No.: 142103-12-6
Research Areas:
5-Me-3’-dU-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
Cat. No.: HY-177363
CAS No.: 2243974-81-2
Target:
Research Areas:
Morpholino G phosphoramidite (Compound 4b) is a nucleoside building block that is used for synthesis of morpholino oligonucleotides. Morpholino G phosphoramidite can be used for oligonucleotide therapies research .
Cat. No.: HY-154545
CAS No.: 256223-93-5
Research Areas:
3’-O-MOE-5MeU-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
Cat. No.: HY-154721
CAS No.: 178925-48-9
Research Areas:
5’-O-DMTr-5-iodo-2’-dU-3’-CED phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
Cat. No.: HY-177385
CAS No.: 2304678-30-4
Target:
Research Areas:
Morpholino C phosphoramidite (Compound 4c) is a nucleoside building block that can be used for synthesis of morpholino oligonucleotides. Morpholino C phosphoramidite can be used for oligonucleotide therapies research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
