179479-03-9
Chemical Structure
3’-O-Me-C(Bz)-2’-phosphoramidite
- CAS No.: 179479-03-9
- Formula:C47H54N5O9P
- Molecular Weight:863.93
IUPAC Name: (2R,3R,4R,5R)-2-(4-benzamido-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) (diisopropylphosphanyl)phosphonite
InChIKey: BENGZEFYMXNUAR-VKBHKTMGSA-N
SMILES: O=C(N=C(NC(C1=CC=CC=C1)=O)C=C2)N2[C@@H]3O[C@H](COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)[C@@H](OC)[C@H]3OP(OCCC#N)N(C(C)C)C(C)C
Biological Activity: 3’-O-Me-C(Bz)-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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3’-O-Me-C(Bz)-2’-phosphoramidite | 96.06% | 3’-O-Me-C(Bz)-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | ||||||||||||||||||||
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Keywords
