1 Result for "

p-Aurora A

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "p-Aurora A" in MCE Product Catalog:

Cat. No.: HY-189415
Research Areas:  

Cancer

Aurora A/HDAC-IN-1 is an orally active dual inhibitor of Aurora A and pan-HDAC (IC50 = 5.61 μM and 0.31 μM). Aurora A/HDAC-IN-1 induces apoptosis and G2/M cell cycle arrest through downregulating p-Aurora A and increasing Ac-H3 and Ac-α-tubulin acetylation, and exhibits broad-spectrum antiproliferative activity. Aurora A/HDAC-IN-1 can be used for research on leukemia and colorectal cancer .
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