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Results for "

phenolic metabolites

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AP-1 (1) Apoptosis (4) Bacterial (1) Biochemical Assay Reagents (1) COX (1) Cytochrome P450 (1) Drug Derivative (1) Drug Metabolite (10) Endogenous Metabolite (10) Environmental Pollutants (2) Herbicide (1) Isotope-Labeled Compounds (3) NF-κB (1) Reference Standards (5) TNF Receptor (1) Tyrosinase (2)
By Research Areas:	Cancer (5) Cardiovascular Disease (1) Infection (1) Inflammation/Immunology (3) Metabolic Disease (6)

Inhibitors & Agonists

Screening Libraries

Natural
Products

Isotope-Labeled Compounds

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-108692

Enterolactone	Apoptosis Endogenous Metabolite	Cancer
Enterolactone is a bioactive phenolic metabolite known as a mammalian lignan derived from dietary lignans. Enterolactone has estrogenic properties and anti-breast cancer activity . Enterolactone is a radiosensitizer for human breast cancer cell lines through impaired DNA repair and increased apoptosis .

HY-Y0801

2,6-Dihydroxybenzoic acid	Drug Metabolite	Others
2,6-Dihydroxybenzoic acid is an aromatic compound containing phenolic hydroxyl groups and carboxyl groups, and it is a secondary metabolite of Salicylic acid (HY-B0167). 2,6-Dihydroxybenzoic acid is also present in olive oil wastewater .

HY-G0004

Acetaminophen metabolite 3-hydroxy-acetaminophen 3-Hydroxyacetaminophen	Drug Metabolite	Inflammation/Immunology
Acetaminophen metabolite 3-hydroxy-acetaminophen (3-Hydroxyacetaminophen) is a non-toxic metabolite and antioxidant of acetaminophen (HY-66005) with free radical scavenging activity. Acetaminophen metabolite 3-hydroxy-acetaminophen can reduce oxidative damage by exerting electron donation ability and antioxidant activity through phenolic hydroxyl groups. 3-hydroxy-acetaminophen can be used to study the toxicity mechanism and drug metabolism of acetaminophen .

HY-N7513

Homovanillyl alcohol	TNF Receptor Drug Metabolite	Cardiovascular Disease
Homovanillyl alcohol is a biological metabolite of Hydroxytyrosol. Hydroxytyrosol is a phenolic compound that is present in virgin olive oil (VOO) and wine. Homovanillyl alcohol protects red blood cells (RBCs) from oxidative injury and has protective effect on cardiovascular disease .

HY-113283R

Homogentisic acid (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
Homogentisic acid (Standard) is the analytical standard of Homogentisic acid. This product is intended for research and analytical applications. Homogentisic acid is a specific metabolite that accumulates in the urine and serum. Homogentisic acid can be used for diagnosis of alkaptonuria. Homogentisic acid is a phenolic acid .

HY-113283S

Homogentisic acid-13C6	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
Homogentisic acid- ¹³C₆ is the ¹³C-labeled Homogentisic acid (HY-113283). Homogentisic acid is a specific metabolite that accumulates in the urine and serum. Homogentisic acid can be used for diagnosis of alkaptonuria. Homogentisic acid is a phenolic acid .

HY-W007671

H-Tyr-OMe 1 Publications Verification	Endogenous Metabolite Tyrosinase	Others
H-Tyr-OMe is an endogenous metabolite. H-Tyr-OMe quenches the fluorescence of carbon dots by oxidizing the phenolic hydroxyl group to quinone under the catalysis of Tyrosinase, and its amino and thiol binding ability can respond to changes in the concentration of biothiols .

HY-W010115

Carbofuran phenol	Environmental Pollutants Drug Metabolite	Others
Carbofuran phenol is a hydrolytic metabolite of the Carbofuran pesticide. Carbofuran phenol is promising for research of environmental bioremediation fields .

HY-108692R

Enterolactone (Standard)	Reference Standards Apoptosis Endogenous Metabolite	Cancer
Enterolactone (Standard) is the analytical standard of Enterolactone. This product is intended for research and analytical applications. Enterolactone is a bioactive phenolic metabolite known as a mammalian lignan derived from dietary lignans. Enterolactone has estrogenic properties and anti-breast cancer activity . Enterolactone is a radiosensitizer for human breast cancer cell lines through impaired DNA repair and increased apoptosis .

HY-119983

7H-Dibenzo[c,g]carbazole DBC	Environmental Pollutants Cytochrome P450	Cancer
7H-Dibenzo[c,g]carbazole (DBC) is an azaarene with high lipophilicity. 7H-Dibenzo[c,g]carbazole has carcinogenic activity and induce DNA adducts in fish, DNA adducts, mutations in diploid human fibroblasts and micronuclei in human blood lymphocytes. 7H-Dibenzo[c,g]carbazole is activated by cytochrome P450 enzymes resulting mainly in the generation of phenolic metabolites .

HY-N17235

4-MeCat-2-sulfate	Drug Metabolite	Metabolic Disease
4-MeCat-2-sulfate is a phenolic metabolite. 4-MeCat-2-sulfate can be detected in plasma after ingestion of fruit pure´e .

HY-W328786

4-Hydroxy-BHT	Drug Metabolite	Metabolic Disease
4-Hydroxy-BHT is metabolite of Butylated hydroxytoluene (HY-Y0172) and used as an indicator of exposure to Butylated hydroxytoluene. Butylated hydroxytoluene is a phenolic antioxidant used widely in processed foods and petroleum products .

HY-162297

4-(Sulfooxy)benzoic acid	Drug Metabolite	Others
4-(Sulfooxy)benzoic acid is a sulfated phenolic acid found in C. elegans. 4-(Sulfooxy)benzoic acid is a metabolite of ethyl para-hydroxybenzoate and several flavonoids .

HY-125909

Phenolic acid	Endogenous Metabolite	Metabolic Disease
Phenolic acid is an endogenous metabolite.

HY-118247

Ro 14-6113	Drug Metabolite	Others
Ro 14-6113 is an inactive phenolic metabolite of the "carotenoid" Ro 15-0778, a form of vitamin A.

HY-153993

Pyrocatechol sulfate	Endogenous Metabolite	Others
Pyrocatechol sulfate is a phenolic metabolite present in human blood plasma, associated with the intake of certain foods such as berries and the status of the gut microbiota. Pyrocatechol sulfate can serve as a biomarker for uremia. Along with other phenolic sulfates, Pyrocatechol sulfate plays a role in regulating various biological functions, including those related to brain health and the rhythmic beating of cardiomyocytes .

HY-W007671R

H-Tyr-OMe (Standard)	Reference Standards Endogenous Metabolite Tyrosinase	Others
H-Tyr-OMe is an endogenous metabolite. H-Tyr-OMe quenches the fluorescence of carbon dots by oxidizing the phenolic hydroxyl group to quinone under the catalysis of Tyrosinase, and its amino and thiol binding ability can respond to changes in the concentration of biothiols .

HY-G0004R

Acetaminophen metabolite 3-hydroxy-acetaminophen (Standard) 3-Hydroxyacetaminophen (Standard)	Reference Standards Drug Metabolite	Inflammation/Immunology
Acetaminophen metabolite 3-hydroxy-acetaminophen (3-Hydroxyacetaminophen) (Standard) is the analytical standard of Acetaminophen metabolite 3-hydroxy-acetaminophen (HY-G0004). This product is intended for research and analytical applications. Acetaminophen metabolite 3-hydroxy-acetaminophen is a non-toxic metabolite and antioxidant of acetaminophen (HY-66005) with free radical scavenging activity. Acetaminophen metabolite 3-hydroxy-acetaminophen can reduce oxidative damage by exerting electron donation ability and antioxidant activity through phenolic hydroxyl groups. 3-hydroxy-acetaminophen can be used to study the toxicity mechanism and drug metabolism of acetaminophen .

HY-116802

Bromobutide	Drug Derivative Herbicide	Others
Bromobutide is an active ingredient in herbicides that kill weeds. Bromobutide has the highest control effect on Scirpus juncoides and Monochloa vaginalis, but has no inhibitory effect on weed seed germination. The main metabolites of bromobutide in rats are alcohol or phenol glucuronides, which enter the enterohepatic circulation .

HY-108692S

Enterolactone-d6	Isotope-Labeled Compounds Apoptosis Endogenous Metabolite	Cancer
Enterolactone-d₆ is the deuterium labeled Enterolactone. Enterolactone is a bioactive phenolic metabolite known as a mammalian lignan derived from dietary lignans. Enterolactone has estrogenic properties and anti-breast cancer activity . Enterolactone is a radiosensitizer for human breast cancer cell lines through impaired DNA repair and increased apoptosis .

HY-W778286

Enterolactone-13C3	Isotope-Labeled Compounds Apoptosis Endogenous Metabolite	Cancer
Enterolactone- ¹³C₃ is the ¹³C-labeled Enterolactone (HY-108692). Enterolactone is a bioactive phenolic metabolite known as a mammalian lignan derived from dietary lignans. Enterolactone has estrogenic properties and anti-breast cancer activity . Enterolactone is a radiosensitizer for human breast cancer cell lines through impaired DNA repair and increased apoptosis .

HY-Y0801R

2,6-Dihydroxybenzoic acid (Standard)	Reference Standards Drug Metabolite	Others
2,6-Dihydroxybenzoic acid (Standard) is the analytical standard of 2,6-Dihydroxybenzoic acid (HY-Y0801). This product is used for research and analytical applications. 2,6-Dihydroxybenzoic acid is an aromatic compound containing phenolic hydroxyl groups and carboxyl groups, and it is a secondary metabolite of Salicylic acid (HY-B0167). 2,6-Dihydroxybenzoic acid is also present in olive oil wastewater .

HY-W844141

2,5-Dimethylchroman-4-one	Others	Others
2,5-Dimethylchroman-4-one is a Phenols product that can be isolated from the metabolites of Alternaria brassicicola ML-P08. .

HY-W654215

Homovanillic acid sulfate sodium	Biochemical Assay Reagents	Metabolic Disease
Homovanillic acid sulfate (sodium) is a phenol that can be found in olive oil and a dopamine metabolite. Homovanillic acid sulfate (sodium) increases in response to acute renal injury in vivo. Homovanillic acid sulfate (sodium) can be used as a biomarker for early detection of kidney disease .

HY-N16448

Xanthoascin	Bacterial	Infection
Xanthoascin (Compound 1) is a natural phenolic metabolite with strong anti plant pathogen activity. Xanthoascin can be extracted from the solid fermentation product of endophytic fungus Aspergillus sp. IFB-YXS isolated from Ginkgo biloba leaves. Xanthoascin has a MIC of 0.3125 µg/mL against Clavibacter michiganense subsp. Sepedonicus and moderate inhibitory activity against other pathogens (MIC = 5-20 µg/mL). Xanthoascin can disrupt the permeability of bacterial cell membranes, leading to nucleic acid leakage .

HY-W016183

2,2'-Biphenol o,o'-Biphenol	COX AP-1 NF-κB	Inflammation/Immunology
2,2'-Biphenol (o,o'-Biphenol) is an anti-inflammatory agent and the major non-protein-bound phenolic metabolite activated by rat bone marrow homogenate and hydrogen peroxide. 2,2'-Biphenol inhibits lipopolysaccharide (LPS) (HY-D1056)-induced COX-2 mRNA and protein expression. 2,2'-Biphenol suppresses the binding of AP-1 and NF-κB to their respective consensus sequences. 2,2'-Biphenol is applicable to research related to inflammation .

Cat. No.	상품명

HY-L021

Natural Product Library	4,974 compounds
Natural products are small molecules produced naturally by any organism including primary and secondary metabolites. Natural sources may lead to basic research on potential bioactive components for commercial development as lead compounds in drug discovery. Nature has been a source of medicinal agents for thousands of years, and an impressive number of modern drugs have been isolated from natural sources, many based on their use in traditional medicine. With the development of new molecular targets, there is an increasing demand for novel molecular diversity for screening. Natural products will play a crucial role in meeting this demand through the continued investigation of world’s bio-diversity, much of which remains unexplored. MCE provides a unique collection of 4,974 natural compounds that contain Saccharides and Glycosides, Phenylpropanoids, Quinones, Flavonoids, Terpenoids and Glycosides, Steroids, Alkaloid, Phenols, Acids and Aldehydes. Natural Product Library is a useful tool for drug discovery that can be used for high throughput screening (HTS) and high content screening (HCS).

Natural Product Library

4,974 compounds

Natural products are small molecules produced naturally by any organism including primary and secondary metabolites. Natural sources may lead to basic research on potential bioactive components for commercial development as lead compounds in drug discovery.

Nature has been a source of medicinal agents for thousands of years, and an impressive number of modern drugs have been isolated from natural sources, many based on their use in traditional medicine. With the development of new molecular targets, there is an increasing demand for novel molecular diversity for screening. Natural products will play a crucial role in meeting this demand through the continued investigation of world’s bio-diversity, much of which remains unexplored.

MCE provides a unique collection of 4,974 natural compounds that contain Saccharides and Glycosides, Phenylpropanoids, Quinones, Flavonoids, Terpenoids and Glycosides, Steroids, Alkaloid, Phenols, Acids and Aldehydes. Natural Product Library is a useful tool for drug discovery that can be used for high throughput screening (HTS) and high content screening (HCS).

HY-L021P

Natural Product Library Plus	6,181 compounds
Natural products are small molecules produced naturally by any organism including primary and secondary metabolites. Natural sources may lead to basic research on potential bioactive components for commercial development as lead compounds in drug discovery. Nature has been a source of medicinal agents for thousands of years, and an impressive number of modern drugs have been isolated from natural sources, many based on their use in traditional medicine. With the development of new molecular targets, there is an increasing demand for novel molecular diversity for screening. Natural products will play a crucial role in meeting this demand through the continued investigation of world’s bio-diversity, much of which remains unexplored. MCE provides a unique collection of 6,181 natural compounds that contains Saccharides and Glycosides, Phenylpropanoids, Quinones, Flavonoids, Terpenoids and Glycosides, Steroids, Alkaloid, Phenols, Acids and Aldehydes. Natural Product Library Plus, with more powerful screening capability, further complements Natural Product Library (HY-L021) by adding some compounds with low solubility or solution stability (Part B) to this library. All those supplementary are supplied in powder form.

Natural Product Library Plus

6,181 compounds

MCE provides a unique collection of 6,181 natural compounds that contains Saccharides and Glycosides, Phenylpropanoids, Quinones, Flavonoids, Terpenoids and Glycosides, Steroids, Alkaloid, Phenols, Acids and Aldehydes. Natural Product Library Plus, with more powerful screening capability, further complements Natural Product Library (HY-L021) by adding some compounds with low solubility or solution stability (Part B) to this library. All those supplementary are supplied in powder form.

Cat. No.	상품명	Category	Target	Chemical Structure