83-30-7
83-30-7
Chemical Structure
2,4,6-Trihydroxybenzoic acid
- CAS No.: 83-30-7
- Formula:C7H6O5
- Molecular Weight:170.12
IUPAC Name: 2,4,6-trihydroxybenzoic acid
InChIKey: IBHWREHFNDMRPR-UHFFFAOYSA-N
SMILES: O=C(O)C1=C(O)C=C(O)C=C1O
Biological Activity: 2,4,6-Trihydroxybenzoic acid is a CDK inhibitor that dose-dependently inhibits recombinant CDK1, CDK2, and CDK4 with IC50 values of 580, 262, and 403 μM, respectively. 2,4,6-Trihydroxybenzoic acid is also a flavonoid metabolite. Cellular uptake of 2,4,6-Trihydroxybenzoic acid depends on functional SLC5A8. 2,4,6-Trihydroxybenzoic acid can be used in colorectal cancer-related research[1][2].
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2,4,6-Trihydroxybenzoic acid | 98.87% | 2,4,6-Trihydroxybenzoic acid is a CDK inhibitor that dose-dependently inhibits recombinant CDK1, CDK2, and CDK4 with IC50 values of 580, 262, and 403 μM, respectively. 2,4,6-Trihydroxybenzoic acid is also a flavonoid metabolite. Cellular uptake of 2,4,6-Trihydroxybenzoic acid depends on functional SLC5A8. 2,4,6-Trihydroxybenzoic acid can be used in colorectal cancer-related research. | ||||||||||||||||||||
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2,4,6-Trihydroxybenzoic acid (Standard) | 99.62% | 2,4,6-Trihydroxybenzoic acid (Standard) is the analytical standard of 2,4,6-Trihydroxybenzoic acid (HY-W077292). This product is intended for research and analytical applications. 2,4,6-Trihydroxybenzoic acid is a CDK inhibitor that dose-dependently inhibits recombinant CDK1, CDK2, and CDK4 with IC50 values of 580, 262, and 403 μM, respectively. 2,4,6-Trihydroxybenzoic acid is also a flavonoid metabolite. Cellular uptake of 2,4,6-Trihydroxybenzoic acid depends on functional SLC5A8. 2,4,6-Trihydroxybenzoic acid can be used in colorectal cancer-related research. | ||||||||||||||||||||
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References
- [1]. Sankaranarayanan R, et al. The Flavonoid Metabolite 2,4,6-Trihydroxybenzoic Acid Is a CDK Inhibitor and an Anti-Proliferative Agent: A Potential Role in Cancer Prevention. Cancers. 2019 Mar 26;11(3):427. [Content Brief]
- [2]. Lee PY, et al. Toxicity and quantitative structure-activity relationships of benzoic acids to Pseudokirchneriella subcapitata. Journal of hazardous materials. 2009 Jun 15;165(1-3):156-61.
