2380-78-1
Chemical Structure
Homovanillyl alcohol
- CAS No.: 2380-78-1
- Formula:C9H12O3
- Molecular Weight:168.19
IUPAC Name: 4-(2-hydroxyethyl)-2-methoxyphenol
InChIKey: XHUBSJRBOQIZNI-UHFFFAOYSA-N
SMILES: OCCC1=CC=C(O)C(OC)=C1
Biological Activity: Homovanillyl alcohol is a biological metabolite of Hydroxytyrosol, and belongs to the class of phenolic organic compounds. Homovanillyl alcohol alleviates cellular oxidative stress and inflammatory responses by scavenging free radicals, inhibiting the phosphorylation of the p38 and JNK MAP kinase pathways, as well as suppressing NF-κB-driven transcription and nuclear translocation. It can be used in studies related to cardiovascular diseases and allergic asthma[1][2][3][4][5].
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Homovanillyl alcohol | 99.84% | Homovanillyl alcohol is a biological metabolite of Hydroxytyrosol, and belongs to the class of phenolic organic compounds. Homovanillyl alcohol alleviates cellular oxidative stress and inflammatory responses by scavenging free radicals, inhibiting the phosphorylation of the p38 and JNK MAP kinase pathways, as well as suppressing NF-κB-driven transcription and nuclear translocation. It can be used in studies related to cardiovascular diseases and allergic asthma. | ||||||||||||||||||||
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Homovanillyl alcohol (Standard) | ≥98% | Homovanillyl alcohol (Standard) is the analytical standard of Homovanillyl alcohol (HY-N7513). This product is intended for research and analytical applications. Homovanillyl alcohol is a biological metabolite of Hydroxytyrosol, and belongs to the class of phenolic organic compounds. Homovanillyl alcohol alleviates cellular oxidative stress and inflammatory responses by scavenging free radicals, inhibiting the phosphorylation of the p38 and JNK MAP kinase pathways, as well as suppressing NF-κB-driven transcription and nuclear translocation. It can be used in studies related to cardiovascular diseases and allergic asthma. | ||||||||||||||||||||
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References
- [1]. Kottayi A, et al. The One-Step Synthesis of Biologically Active Isochromans from Lignin-Derived Aromatic Monomers in Tunable Deep Eutectic Solvents. Chemistry (Weinheim an der Bergstrasse, Germany). 2026 Aug 13;32(30):e02769.
- [2]. De la Torre R, et al. Protective effect of homovanillyl alcohol on cardiovascular disease and total mortality: virgin olive oil, wine, and catechol-methylation. The American journal of clinical nutrition. 2017 Jun;105(6):1297-1304. [Content Brief]
- [3]. Xiao H, et al. Mycobacterium vaccae alleviates allergic airway inflammation and airway hyper-responsiveness in asthmatic mice by altering intestinal microbiota. Immunology. 2024 Apr;171(4):595-608.
- [4]. Paiva-Martins F, et al. Protective activity of hydroxytyrosol metabolites on erythrocyte oxidative-induced hemolysis. Journal of agricultural and food chemistry. 2013 Jul 10;61(27):6636-42. [Content Brief]
- [5]. Serreli G, et al. In vivo formed metabolites of polyphenols and their biological efficacy. Food & function. 2019 Nov 01;10(11):6999-7021.
