4 Results for "

physiological fission

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "physiological fission" in MCE Product Catalog:

4
Diethyl succinate
Diethyl succinate
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4 Cited Publications
Cat. No.: HY-Y0836
CAS No.: 123-25-1
Synonyms: Diethyl Butanedioate
Category:  

Natural Products other families Metabolic Disease Plants Disease Research Fields

Target:  

Environmental Pollutants Biochemical Assay Reagents Reactive Oxygen Species (ROS)

Diethyl succinate (Diethyl Butanedioate) can be utilized at physiological pH, allowing it to penetrate biological membranes and integrate into the cells of tissue cultures, where it is metabolized via the tricarboxylic acid cycle. Diethyl succinate modulates the polarization and activation of microglial cells by reducing mitochondrial fission and the levels of reactive oxygen species (ROS), thereby exerting an inflammatory protective effect in primary microglial cells. Furthermore, Diethyl succinate is non-toxic and can be used in flavorings and seasonings .
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IIQLPEIVVV TFA
IIQLPEIVVV TFA
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Cat. No.: HY-P6374
Target:  

Dynamin

Research Areas:  

Neurological Disease

IIQLPEIVVV TFA is a specific inhibitor of Drp1-Mff interaction. IIQLPEIVVV TFA can distinguish physiological from pathological fission and block physiological fission, thus leading to mitochondrial dysfunction. IIQLPEIVVV TFA can be used in the study of Huntington's disease .
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P259
P259
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Cat. No.: HY-P11005
Target:  

Dynamin ATP Synthase

Research Areas:  

Neurological Disease

P259 is a Drp1-Mff inhibitor. P259 distinguishes physiological from pathological fission by specifically inhibiting Drp1-Mff interaction. P259 elongates cell mitochondria and disrupts mitochondrial function and motility. P259 reduces ATP levels and alters mitochondrial structure in the brain, resulting in behavioral deficits in wild-type mice and a short lifespan in Huntington's disease (HD) mice model .
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Diethyl succinate (Standard)
Diethyl succinate (Standard)
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Cat. No.: HY-Y0836R
CAS No.: 123-25-1
Synonyms: Diethyl Butanedioate (Standard)
Category:  

Natural Products other families Microorganisms Plants

Target:  

Biochemical Assay Reagents Reference Standards Reactive Oxygen Species (ROS)

Diethyl succinate (Standard) is the analytical standard of Diethyl succinate. This product is intended for research and analytical applications. Diethyl succinate (Diethyl Butanedioate) can be utilized at physiological pH, allowing it to penetrate biological membranes and integrate into the cells of tissue cultures, where it is metabolized via the tricarboxylic acid cycle. Diethyl succinate modulates the polarization and activation of microglial cells by reducing mitochondrial fission and the levels of reactive oxygen species (ROS), thereby exerting an inflammatory protective effect in primary microglial cells. Furthermore, Diethyl succinate is non-toxic and can be used in flavorings and seasonings .
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