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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
protein farnesyl transferase
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "protein farnesyl transferase" in MCE Product Catalog:
Art. -Nr.: HY-16111
CAS. Nr.: 195987-41-8
Target:
Forschungsgebiete:
BMS-214662 is a farnesyl transferase inhibitor. BMS-214662 can effectively block the localization and function of Ras protein in the cell membrane by inhibiting the pro-group modification of Ras protein, thereby exerting anti-tumor activity. BMS-214662 has an IC50 value of 1.3 nM for H-Ras and 8.4 nM for K-Ras. BMS-214662 can be used to study Ras-related tumor diseases .
Art. -Nr.: HY-15873
CAS. Nr.: 170006-72-1
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Forschungsgebiete:
FTI-276 is a protein farnesyl transferase (PFT) inhibitor with IC50s of 0.9 and 0.5 nM for Plasmodium falciparum and human.
Art. -Nr.: HY-16111A
CAS. Nr.: 195981-08-9
Target:
Forschungsgebiete:
BMS-214662 hydrochloride is an inhibitor of farnesyltransferase (Farnesyl Transferase). BMS-214662 hydrochloride can effectively block the localization and function of Ras proteins on the cell membrane by inhibiting the prenylation modification of Ras proteins, thereby exerting anti-tumor activity. The IC50 value of BMS-214662 hydrochloride for H-Ras is 1.3 nM, and for K-Ras it is 8.4 nM. BMS-214662 hydrochloride can be used in the research of tumor diseases related to Ras .
Art. -Nr.: HY-N2150
CAS. Nr.: 110659-91-1
Art. -Nr.: HY-W022657
CAS. Nr.: 85391-05-5
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Forschungsgebiete:
Art. -Nr.: HY-118426
CAS. Nr.: 192185-68-5
Synonyms: (Rac)-IND 58359; (Rac)-R115777
Target:
Forschungsgebiete:
(Rac)-Tipifarnib ((Rac)-IND 58359; (Rac)-R115777) is a potent farnesyl protein transferase inhibitor that specifically targets the pro-tailation process of Ras proteins. (Rac)-Tipifarnib showed significant in vivo antitumor effects after oral administration to mice .
Art. -Nr.: HY-126871
CAS. Nr.: 155179-15-0
Category:
Target:
Art. -Nr.: HY-134579
CAS. Nr.: 148796-51-4
Category:
Target:
Art. -Nr.: HY-183458
CAS. Nr.: 655234-81-4
Target:
Forschungsgebiete:
FTI-2628 is an antimalarial agent and a farnesyl transferase inhibitor, with an IC50 of 41.7 nM against TbPET. FTI-2628 attenuates glucose-stimulated insulin secretion. FTI-2628 exhibits antimalarial activity against Trypanosoma brucei .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
