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pyridoxal kinase

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By Targets:	Endogenous Metabolite (4) Reference Standards (2)
By Research Areas:	Cardiovascular Disease (1) Metabolic Disease (4) Neurological Disease (5)

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Art. -Nr.	Produktname	Target	Forschungsgebiete	Chemical Structure

HY-W027446

Pyridoxal hydrochloride 1 Publications Verification	Endogenous Metabolite	Neurological Disease Metabolic Disease
Pyridoxal hydrochloride, the hydrochloride form of Pyridoxal (HY-107469), is a newly developed neuroprotective agent. Pyridoxal hydrochloride is one of the major forms of vitamin B6. Pyridoxal hydrochloride is solvolyzed in methanol to form pyridoxal monomethylacetal. Pyridoxal is phosphorylated by pyridoxal kinase to Pyridoxal phosphate (HY-B1744). Pyridoxal is oxidized by the liver to 4-Pyridoxic acid (HY-113493) which is excreted in the urine. Pyridoxal hydrochloride is proming for research of carpal tunnel syndrome (CTS) .

HY-N8157

4'-O-Methylpyridoxine 1 Publications Verification	Others	Cardiovascular Disease Neurological Disease
4'-O-Methylpyridoxine is an orally active antivitamin B6 compound found in Ginkgo biloba seeds and leaves. 4'-O-Methylpyridoxine inhibits **pyridoxal kinase*. 4'-O-Methylpyridoxine reduces brain pyridoxal-5'-phosphate (PLP) levels, decreases gamma-aminobutyric acid/glutamate (GABA/Glu) ratio. 4'-O-Methylpyridoxine increases plasma levels of pyridoxal-5'-phosphate and pyridoxal*. 4'-O-Methylpyridoxine induces hyperactivity, convulsions, pathological tissue changes, organ damage in rodent brain and heart .

HY-107469

Pyridoxal 1 Publications Verification pyridoxaldehyde	Endogenous Metabolite	Neurological Disease Metabolic Disease
Pyridoxal is a neuroprotectant. Pyridoxal is one of the main forms of vitamin B6. Pyridoxal is phosphorylated by pyridoxal kinase to pyridoxal phosphate (HY-B1744). Pyridoxal is oxidized by the liver to 4-pyridoxic acid (HY-113493) and excreted in the urine. Pyridoxal has shown promise in the study of carpal tunnel syndrome (CTS) .

HY-107469R

Pyridoxal (Standard) 1 Publications Verification pyridoxaldehyde (Standard)	Endogenous Metabolite Reference Standards	Neurological Disease Metabolic Disease
Pyridoxal (Standard) is the analytical standard of Pyridoxal. This product is intended for research and analytical applications. Pyridoxal is a neuroprotectant. Pyridoxal is one of the main forms of vitamin B6. Pyridoxal is phosphorylated by pyridoxal kinase to pyridoxal phosphate (HY-B1744). Pyridoxal is oxidized by the liver to 4-pyridoxic acid (HY-113493) and excreted in the urine. Pyridoxal has shown promise in the study of carpal tunnel syndrome (CTS)[1][2][3].

HY-W027446R

Pyridoxal hydrochloride (Standard)	Reference Standards Endogenous Metabolite	Neurological Disease Metabolic Disease
Pyridoxal hydrochloride (Standard) is the analytical standard of Pyridoxal hydrochloride. This product is intended for research and analytical applications. Pyridoxal hydrochloride, the hydrochloride form of Pyridoxal (HY-107469), is a newly developed neuroprotective agent. Pyridoxal hydrochloride is one of the major forms of vitamin B6. Pyridoxal hydrochloride is solvolyzed in methanol to form pyridoxal monomethylacetal. Pyridoxal is phosphorylated by pyridoxal kinase to Pyridoxal phosphate (HY-B1744). Pyridoxal is oxidized by the liver to 4-Pyridoxic acid (HY-113493) which is excreted in the urine. Pyridoxal hydrochloride is proming for research of carpal tunnel syndrome (CTS) .

Pyridoxal hydrochloride 1 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Pyridoxal hydrochloride, the hydrochloride form of Pyridoxal (HY-107469), is a newly developed neuroprotective agent. Pyridoxal hydrochloride is one of the major forms of vitamin B6. Pyridoxal hydrochloride is solvolyzed in methanol to form pyridoxal monomethylacetal. Pyridoxal is phosphorylated by pyridoxal kinase to Pyridoxal phosphate (HY-B1744). Pyridoxal is oxidized by the liver to 4-Pyridoxic acid (HY-113493) which is excreted in the urine. Pyridoxal hydrochloride is proming for research of carpal tunnel syndrome (CTS) .

4'-O-Methylpyridoxine 1 Publications Verification	Alkaloids Structural Classification Ginkgoaceae Classification of Application Fields Other Diseases Pyridine Alkaloids Plants Ginkgo biloba Disease Research Fields Source Classification	Others
4'-O-Methylpyridoxine is an orally active antivitamin B6 compound found in Ginkgo biloba seeds and leaves. 4'-O-Methylpyridoxine inhibits **pyridoxal kinase*. 4'-O-Methylpyridoxine reduces brain pyridoxal-5'-phosphate (PLP) levels, decreases gamma-aminobutyric acid/glutamate (GABA/Glu) ratio. 4'-O-Methylpyridoxine increases plasma levels of pyridoxal-5'-phosphate and pyridoxal*. 4'-O-Methylpyridoxine induces hyperactivity, convulsions, pathological tissue changes, organ damage in rodent brain and heart .

Pyridoxal 1 Publications Verification pyridoxaldehyde	Natürliche Produkte Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification Cancer	Endogenous Metabolite
Pyridoxal is a neuroprotectant. Pyridoxal is one of the main forms of vitamin B6. Pyridoxal is phosphorylated by pyridoxal kinase to pyridoxal phosphate (HY-B1744). Pyridoxal is oxidized by the liver to 4-pyridoxic acid (HY-113493) and excreted in the urine. Pyridoxal has shown promise in the study of carpal tunnel syndrome (CTS) .

Pyridoxal (Standard) 1 Publications Verification pyridoxaldehyde (Standard)	Structural Classification Natürliche Produkte Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Endogenous Metabolite Reference Standards
Pyridoxal (Standard) is the analytical standard of Pyridoxal. This product is intended for research and analytical applications. Pyridoxal is a neuroprotectant. Pyridoxal is one of the main forms of vitamin B6. Pyridoxal is phosphorylated by pyridoxal kinase to pyridoxal phosphate (HY-B1744). Pyridoxal is oxidized by the liver to 4-pyridoxic acid (HY-113493) and excreted in the urine. Pyridoxal has shown promise in the study of carpal tunnel syndrome (CTS)[1][2][3].

Pyridoxal hydrochloride (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Pyridoxal hydrochloride (Standard) is the analytical standard of Pyridoxal hydrochloride. This product is intended for research and analytical applications. Pyridoxal hydrochloride, the hydrochloride form of Pyridoxal (HY-107469), is a newly developed neuroprotective agent. Pyridoxal hydrochloride is one of the major forms of vitamin B6. Pyridoxal hydrochloride is solvolyzed in methanol to form pyridoxal monomethylacetal. Pyridoxal is phosphorylated by pyridoxal kinase to Pyridoxal phosphate (HY-B1744). Pyridoxal is oxidized by the liver to 4-Pyridoxic acid (HY-113493) which is excreted in the urine. Pyridoxal hydrochloride is proming for research of carpal tunnel syndrome (CTS) .

Art. -Nr.	Compare	Produktname	Species	Source	Image

HY-P79342

	Pyridoxal Kinase Protein, Human (GST) pyridoxal kinase; PDXK; Pyridoxine kinase; C21orf124; C21orf97; PKH; PNK	Human	E. coli
	Pyridoxal Kinase Protein catalyzes vitamin B6 vitamer phosphorylation—converting pyridoxal (PL), pyridoxine (PN), and pyridoxamine (PM) into active forms: pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PNP), and pyridoxamine 5'-phosphate (PMP) (Probable). PLP serves as the active cofactor in more than 140 enzymatic reactions. Pyridoxal Kinase Protein, Human (His) is the recombinant human-derived Pyridoxal Kinase protein, expressed by E. coli , with N-GST labeled tag.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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pyridoxal kinase

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Recombinant Proteins

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