5 Results for "

renal medulla

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "renal medulla" in MCE Product Catalog:

1
7,8-Dihydro-L-biopterin
7,8-Dihydro-L-biopterin
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1 Cited Publications
Cat. No.: HY-W008646
CAS No.: 6779-87-9
Synonyms: Dihydrobiopterin
Category:  

Human Gut Microbiota Metabolites Natural Products Other Diseases Endogenous metabolite Disease Research Fields

Target:  

SOD Apoptosis NO Synthase

7,8-Dihydro-L-biopterin is a NOS uncoupling inducer with blood-brain barrier permeability, and it is a reduced non-conjugated pteridine. 7,8-Dihydro-L-biopterin is the main metabolite of 4-amino-tetrahydro-L-biopterin, and it undergoes photooxidation to form biopterin. 7,8-Dihydro-L-biopterin promotes the conversion of nitric oxide synthase to a superoxide-producing form, thereby increasing oxidative stress levels in the renal outer medulla and inducing apoptosis. 7,8-Dihydro-L-biopterin is sensitive to the inhibitory effect of SOD, and it can be applied to research related to salt-sensitive hypertension, moderate to severe traumatic brain injury, and neurodegenerative diseases .
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7,8-Dihydro-L-biopterin (Standard)
7,8-Dihydro-L-biopterin (Standard)
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Cat. No.: HY-W008646R
CAS No.: 6779-87-9
Category:  

Human Gut Microbiota Metabolites Natural Products Microorganisms Endogenous metabolite

Target:  

Reference Standards SOD Apoptosis NO Synthase

NADH (disodium salt) (Standard) is the analytical standard of NADH (disodium salt). This product is intended for research and analytical applications. 7,8-Dihydro-L-biopterin is a NOS uncoupling inducer with blood-brain barrier permeability, and it is a reduced non-conjugated pteridine. 7,8-Dihydro-L-biopterin is the main metabolite of 4-amino-tetrahydro-L-biopterin, and it undergoes photooxidation to form biopterin. 7,8-Dihydro-L-biopterin promotes the conversion of nitric oxide synthase to a superoxide-producing form, thereby increasing oxidative stress levels in the renal outer medulla and inducing apoptosis. 7,8-Dihydro-L-biopterin is sensitive to the inhibitory effect of SOD, and it can be applied to research related to salt-sensitive hypertension, moderate to severe traumatic brain injury, and neurodegenerative diseases .
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BIBS 39
BIBS 39
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Cat. No.: HY-19732
CAS No.: 133085-33-3
Target:  

Angiotensin Receptor

Research Areas:  

Cardiovascular Disease

BIBS 39 is a non-peptide angiotensin II receptor antagonist with antihypertensive activity, with higher affinity for the AT1 receptor than for the AT2 receptor. BIBS 39 competitively blocks AT1-mediated vasoconstriction and pressor responses, and effectively inhibits the activity of the renin-angiotensin-aldosterone system. BIBS 39 reduces diastolic blood pressure and induces mild, transient reflex tachycardia, with no off-target functional activity on the norepinephrine, K +/Cl − or vasopressin pathways. BIBS 39 can be used in research related to hypertension and renal hypertension [1][2 ][3].
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E822-1968
E822-1968
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Cat. No.: HY-183637
CAS No.: 1037259-63-4
Target:  

Urea Transporter

Research Areas:  

Cardiovascular Disease Metabolic Disease Endocrinology

E822-1968 is an UT-A2 inhibitor with a human IC50 of 0.44 μM. E822-1968 blocks urea transport mediated by UT-A2. E822-1968 can be used for the study of hyponatremia and edema associated with congestive heart failure, nephrotic syndrome, and cirrhosis .
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Prostaglandin A2 ethyl ester
Prostaglandin A2 ethyl ester
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Cat. No.: HY-172817
Target:  

Drug Derivative

Research Areas:  

Cardiovascular Disease Inflammation/Immunology

Prostaglandin A2 ethyl ester is an ethyl ester derivative of Prostaglandin A2 (HY-113041). Prostaglandin A2 ethyl ester exhibits vasodilatory activity and has a protective effect on the kidneys .
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