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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
renal transplant
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "renal transplant" in MCE Product Catalog:
Synonyms: CHI 621
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Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
Cat. No.: HY-P990083
CAS No.: 2628092-47-5
Synonyms: AT-1501
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BMS-566419 is an orally active IMPDH inhibitor with an IC50 of 91 nM against human IMPDH I and 68 nM against human IMPDH II. BMS-566419 exerts anti-heart transplant rejection and anti-renal fibrosis effects, and inhibits the expression of MCP-1, TGF-β1 as well as antibody production. BMS-566419 can be used in research on renal fibrosis and organ transplantation .
Cat. No.: HY-P99257
CAS No.: 1453067-91-8
Synonyms: ASKP 1240
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Cat. No.: HY-P991557
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Cat. No.: HY-P990083A
CAS No.: 2628092-47-5
Synonyms: AT-1501 (powder)
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Cat. No.: HY-185926
CAS No.: 2364414-05-9
Synonyms: NOX-D21; AON-D21
Research Areas:
Ldalaptican pegol (AON-D21; NOX-D21) is a PEGylated mixed RNA/DNA L-aptamer that specifically binds to complement C5a. Ldalaptican pegol binds to C5a and the C5a moiety on uncleaved C5, thereby blocking C5a signaling. This inhibition suppresses downstream inflammatory responses, immune cell infiltration and chemotaxis, the release of pro-fibrotic factors, and abnormalities in lipid metabolism signaling pathways. Ldalaptican pegol can also alleviate allograft rejection. Ldalaptican pegol can be used in research on inflammatory muscle diseases, Duchenne muscular dystrophy (DMD), diabetes, renal fibrosis, and allograft organ transplant rejection .
Cat. No.: HY-P12125
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
