11 Results for "

skeletal muscle myoblasts

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "skeletal muscle myoblasts" in MCE Product Catalog:

1
Trevogrumab
Trevogrumab
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1 Cited Publications
Cat. No.: HY-P99388
CAS No.: 1429201-24-0
Synonyms: REGN-1033; SAR391786

Target:  

TGF-beta/Smad

Research Areas:  

Inflammation/Immunology

Trevogrumab (REGN-1033) is a monoclonal antibody targeting GDF8 (growth differentiation factor 8, also known as myostatin). Trevogrumab is used in research on muscle wasting conditions, including disuse atrophy, chronic diseases, and changes in food and nutrient intake .
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N-p-trans-Coumaroyltyramine
N-p-trans-Coumaroyltyramine
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1 Cited Publications
Cat. No.: HY-N2230
CAS No.: 36417-86-4
Category:  

Ophiopogon japonicus (L. f.) Ker-Gawl. Liliaceae Simple Phenylpropanols Phenols Polyphenols Phenylpropanoids Plants

Target:  

Cholinesterase (ChE) Parasite Glycosidase

N-p-trans-Coumaroyltyramine is a natural phenolic amide compound and an inhibitor of AChE (IC50: 122 μM) and α-glucosidase (IC50: 2.7 μM). N-p-trans-Coumaroyltyramine also has anti-trypanosomal activity, with an IC50 of 13.3 µM against T. brucei rhodesiense. N-p-trans-Coumaroyltyramine can be used in the research of diseases such as Alzheimer's disease .
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Muscle homing peptide M12
Muscle homing peptide M12
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Cat. No.: HY-P10646
CAS No.: 2896181-32-9
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Muscle homing peptide M12 is a muscle-homing peptide with high affinity for skeletal muscle and cardiac muscle. Muscle homing peptide M12 can mediate the targeted delivery of loaded drugs to skeletal muscle and cardiac muscle tissues .
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2,6-Dimethoxy-1,4-benzoquinone
2,6-Dimethoxy-1,4-benzoquinone
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Cat. No.: HY-N1677
CAS No.: 530-55-2
Category:  

Infection Quinones other families Metabolic Disease Benzene Quinones Plants Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

Akt mTOR Bacterial Fungal AMPK

2,6-Dimethoxy-1,4-benzoquinone is a 1,4-benzoquinone derivative. 2,6-Dimethoxy-1,4-benzoquinone promotes phosphorylation of AKT, S6K, mTOR, 4E-BP1, and AMPK, and attenuates mTORC1 activity as part of the AKT/mTOR pathway. 2,6-Dimethoxy-1,4-benzoquinone stimulates myoblast differentiation, increases myotube size, elevates MHC protein expression, enhances mitochondrial biogenesis, respiration, and DNA content, and increases skeletal muscle weights, fiber size, grip strength, and treadmill performance. 2,6-Dimethoxy-1,4-benzoquinone exerts anti-cancer, anti-inflammatory, anti-adipogenic, antibacterial, and antimutagenic effects, inhibits adipogenic transcription factors, nitric oxide production, skin tumor development, Magnaporthe oryzae growth, spore germination, appressorium formation, and growth of select bacterial species, induces H2O2 generation and rice defense gene expression, and reduces rice blast lesion formation. 2,6-Dimethoxy-1,4-benzoquinone can be used for the research of obesity, skin tumorigenesis, rice blast disease, and food-borne illness .
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(±)-1,2-Diolein
(±)-1,2-Diolein
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Cat. No.: HY-115767
CAS No.: 2442-61-7
Synonyms: 1,2-Dioleoyl-rac-glycerol
Target:  

PKC

Research Areas:  

Others

(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein increases myotubes Ca 2+ influx .
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QC-308 hydrochloride
QC-308 hydrochloride
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Cat. No.: HY-134310
CAS No.: 1353586-18-1
Target:  

Heme Oxygenase (HO)

Research Areas:  

Inflammation/Immunology

QC-308 hydrochloride is a HO-1/HO-2 inhibitor, with an IC50 of 0.27 μM against rat HO-1 and an IC50 of 0.46 μM against rat HO-2. QC-308 hydrochloride inhibits the activities of rat HO-1 and HO-2 in carbon monoxide generation assays using spleen and brain microsomes, respectively. QC-308 hydrochloride also exhibits senolytic activity, reducing the survival rate of adipogenic progenitor cells in skeletal muscle fibers of senescent mice and human skeletal muscle myoblasts. QC-308 hydrochloride is applicable for senescence-related research .
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QC-308
QC-308
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Cat. No.: HY-182604
CAS No.: 1353712-58-9
Target:  

Heme Oxygenase (HO)

Research Areas:  

Inflammation/Immunology

QC-308 is a HO-1/HO-2 inhibitor, with an IC50 of 0.27 μM against rat HO-1 and an IC50 of 0.46 μM against rat HO-2. QC-308 inhibits the activities of rat HO-1 and HO-2 in carbon monoxide generation assays using spleen and brain microsomes, respectively. QC-308 also exhibits senolytic activity, reducing the survival rate of adipogenic progenitor cells in skeletal muscle fibers of senescent mice and human skeletal muscle myoblasts. QC-308 is applicable for senescence-related research .
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2,6-Dimethoxy-1,4-benzoquinone (Standard)
2,6-Dimethoxy-1,4-benzoquinone (Standard)
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Cat. No.: HY-N1677R
CAS No.: 530-55-2
Category:  

Quinones other families Benzene Quinones Plants Endogenous metabolite

Target:  

Reference Standards Akt mTOR Bacterial Fungal AMPK

2,6-Dimethoxy-1,4-benzoquinone (Standard) is the analytical standard of 2,6-Dimethoxy-1,4-benzoquinone (HY-N1677). This product is intended for research and analytical applications. 2,6-Dimethoxy-1,4-benzoquinone is a 1,4-benzoquinone derivative. 2,6-Dimethoxy-1,4-benzoquinone promotes phosphorylation of AKT, S6K, mTOR, 4E-BP1, and AMPK, and attenuates mTORC1 activity as part of the AKT/mTOR pathway. 2,6-Dimethoxy-1,4-benzoquinone stimulates myoblast differentiation, increases myotube size, elevates MHC protein expression, enhances mitochondrial biogenesis, respiration, and DNA content, and increases skeletal muscle weights, fiber size, grip strength, and treadmill performance. 2,6-Dimethoxy-1,4-benzoquinone exerts anti-cancer, anti-inflammatory, anti-adipogenic, antibacterial, and antimutagenic effects, inhibits adipogenic transcription factors, nitric oxide production, skin tumor development, Magnaporthe oryzae growth, spore germination, appressorium formation, and growth of select bacterial species, induces H2O2 generation and rice defense gene expression, and reduces rice blast lesion formation. 2,6-Dimethoxy-1,4-benzoquinone can be used for the research of obesity, skin tumorigenesis, rice blast disease, and food-borne illness.
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Ilekudinol B
Ilekudinol B
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Cat. No.: HY-N17326
CAS No.: 242794-72-5
Category:  

Weigela subsessilis (Nakai) L.H.Bailey Caprifoliaceae Terpenoids Plants Pentacyclic Triterpenoids

Target:  

Acyltransferase Phosphatase Interleukin Related

Ilekudinol B is an inhibitor of ACAT and PTP1B, with an IC50 of 5.3 μM and a Ki of 11.6 μM against human PTP1B. Ilekudinol B inhibits the classical pathway of the complement system, with an IC50 of 51 μM. Ilekudinol B inhibits TNF-α-induced cellular IL-8 secretion, promotes glucose uptake in skeletal muscle myotubes, and acts as an insulin mimetic and insulin sensitizer. Ilekudinol B can be used in research related to type 2 diabetes, obesity, and inflammatory diseases .
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BV2
BV2
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Cat. No.: HY-P11741
Target:  

Exosomes Biochemical Assay Reagents

Research Areas:  

Neurological Disease

BV2 is a delivery peptide that binds to BVES, with a Ka of 2.03 μM for the BVES target. BV2 specifically binds to the extracellular domain of BVES, achieving muscle homing and cellular internalization via caveolae-mediated endocytosis. When BV2 is modified on the surface of exosomes by PMO, it enhances dystrophin restoration in the peripheral muscles and myocardium of dystrophin-deficient mice. BV2 is applicable to research related to Duchenne muscular dystrophy and muscle atrophy .
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rG4 mut_AHPC_PEG2
rG4 mut_AHPC_PEG2
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Cat. No.: HY-185724
Target:  

PROTACs G-quadruplex

Research Areas:  

Others

rG4 mut_AHPC_PEG2 is a structure-disruptive negative control PROTAC. rG4 mut_AHPC_PEG2 demonstrates that the RNA G-quadruplex conformation is an absolute prerequisite for the recruitment and degradation of DHX36 by retaining the E3-recruiting moiety (AHPC-PEG2) while disrupting the secondary structure of the nucleic acid moiety (mutated RNA G-quadruplex), .
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