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synthetic reagents

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11

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2

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8

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17

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3

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0389A
    D-Glucose-13C6
    15+ Cited Publications

    Glucose-13C6; D-(+)-Glucose-13C6; Dextrose-13C6

    		 Endogenous Metabolite Metabolic Disease
    D-Glucose- 13C6 is a stable isotope-labeled counterpart of D-glucose (HY-B0389). D-Glucose- 13C6 can be used as a metabolic tracer to trace glucose-related synthetic catabolism or as synthesis ingredient, minimal media reagent, and internal standard .
    D-Glucose-13C6
  • HY-136314
    DBCO-PEG4-VC-PAB-MMAE

    		Drug-Linker Conjugates for ADC Cancer
    DBCO-PEG4-VC-PAB-MMAE consists a ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE (HY-15162). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-agent conjugates (ADCs). MMAE is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. DBCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-PEG4-VC-PAB-MMAE
  • HY-N7137
    Norgestrel
    1 Publications Verification

    		 Reactive Oxygen Species (ROS) Neurological Disease Cancer
    Norgestrel is a synthetic analog of progesterone, a compound commonly found in oral contraceptive pill, and a powerful neuroprotective antioxidant, preventing light-induced ROS in photoreceptor cells, and cell death . Norgestrel is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Norgestrel
  • HY-W076836
    4-Aminobenzaldehyde

    p-aminobenzaldehyde

    		 Biochemical Assay Reagents Others
    4-Aminobenzaldehyde (p-aminobenzaldehyde) is a useful synthetic reagent and monomer that can be used to synthesize monoazo dyes and photocurable ion exchange resins. 4-Aminobenzaldehyde is also a corrosion inhibitor of metals .
    4-Aminobenzaldehyde
  • HY-W006064
    L-Propargylglycine
    1 Publications Verification

    (S)-2-Aminopent-4-ynoic acid

    		 Amino Acid Derivatives Others
    (S)-2-Aminopent-4-ynoic acid is a synthetic amino acid. (S)-2-Aminopent-4-ynoic acid can be used in synthesis of folate-conjugates and corresponding metal-chelate complexes . (S)-2-Aminopent-4-ynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    L-Propargylglycine
  • HY-101405
    Gestrinone
    1 Publications Verification

    R 2323

    		 Estrogen Receptor/ERR Inflammation/Immunology
    Gestrinone (R2323) is a synthetic steroid hormone used to treat endometriosis. It inhibits leiomyoma cells with an IC50 of 43.67 μM. Gestrinone is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Gestrinone
  • HY-W013172
    Norgestimate

    		Progesterone Receptor Endocrinology
    Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity. Norgestimate is used for an oral contraceptive . Norgestimate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Norgestimate
  • HY-108039
    Bezisterim

    HE 3286; NE-3107

    		 NF-κB Neurological Disease Metabolic Disease Inflammation/Immunology
    Bezisterim (HE 3286; NE-3107) is a synthetic derivative of a natural anti-inflammatory steroid, β-AET. Bezisterim is an orally active partial NF-κB inhibitor. HE3286 reduces proinflammatory signals, including IL-6 and matrix metallopeptidase 3. Bezisterim freely penetrates the blood brain barrier in mice. Bezisterim can be used for the research of the ulcerative colitis, arthritis, experimental autoimmune encephalomyelitis . Bezisterim is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Bezisterim
  • HY-145149
    Duostatin 5

    		ADC Payload Cancer
    Duostatin 5 is a ADC Cytotoxin designed based on MMAF (HY-15579) and can be used to synthesize ADCs. The preparation of Duostatin 5 has the advantages of fewer synthetic steps, simple operation, less difficulty in quality control, and more stable chemical synthesis process. Duostatin 5 can be linked to the antibody targeting 5T4 (ZV05) by cross-linking with interchain cysteines through a disubstituted C-Lock linker. Duostatin 5 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups[1][2].
    Duostatin 5
  • HY-W016618
    Ethyl phenylglyoxylate

    Ethyl benzoylformate; Phenylglyoxylic acid ethyl ester

    		 Drug Intermediate Biochemical Assay Reagents Carboxylesterase (CES) Others
    Ethyl phenylglyoxylate (Ethyl benzoylformate), the ethyl ester of phenylglyoxylic acid, is used as a synthetic reagent. Ethyl phenylglyoxylate is also a poor substrate but a potent inhibitor of chicken liver carboxylesterase. Additionally, Ethyl phenylglyoxylate exhibits photoreactivity, where its excited triplet carbonyl can initiate intermolecular hydrogen abstraction, radical coupling and cross-linking reactions .
    Ethyl phenylglyoxylate
  • HY-59125
    (R,R)-(+)-Hydrobenzoin

    		Endogenous Metabolite Others
    (R,R)-(+)-Hydrobenzoin is a chiral secondary alcohol that can be used as a key substrate or a chiral auxiliary reagent in various catalytic reactions and synthetic experiments .
    (R,R)-(+)-Hydrobenzoin
  • HY-B0257S1
    Norgestrel-d6

    		Isotope-Labeled Compounds Progesterone Receptor Endocrinology
    Norgestrel-d6 is the deuterium labeled Levonorgestrel. Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives. Norgestrel-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Norgestrel-d6
  • HY-B2091
    Azidocillin

    		Antibiotic Bacterial Infection
    Azidocillin, a semi-synthetic Penicillin, is an orally active β-lactam antibiotic. Azidocillin bears an azide functionality and retains on-target activity within bacteria. Azidocillin can be used to research osteitis caused by dental surgery, otitis media, enterococcal septicemia and other bacterial infectious diseases . Azidocillin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Azidocillin
  • HY-Y0373
    tert-Butyl carbazate

    		Biochemical Assay Reagents Drug Intermediate Infection
    tert-Butyl carbazate serves as a starting material for the preparation of heterocyclic and hydrazine derivatives. tert-Butyl carbazate undergoes coupling with aryl, heteroaryl, and alkenyl boronic acids to synthesize doubly protected monosubstituted hydrazines. Derivatives of tert-Butyl carbazate exhibit varying degrees of inhibitory activity against Gram-positive bacteria, Gram-negative bacteria, and various fungi .
    tert-Butyl carbazate
  • HY-W036733
    4-Hydroxy-4-methylcyclohexanone

    		Biochemical Assay Reagents Others
    4-Hydroxy-4-methylcyclohexanone is a useful synthetic reagent extracted from patent JP2009022162A. 4-Hydroxy-4-methylcyclohexanone can be used to synthesize trans-4-amino-1-methylcyclohexanol which is intermediate of pharmaceutical synthesis .
    4-Hydroxy-4-methylcyclohexanone
  • HY-147309
    16-Azidohexadecanoic acid

    		Fluorescent Dye Others
    16-Azidohexadecanoic acid, a synthetic fatty acid, can be used as a modification marker for nucleotides and a molecular probe for fatty acid metabolism . 16-Azidohexadecanoic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    16-Azidohexadecanoic acid
  • HY-P10143
    MMP-2/MMP-9 Substrate

    Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt

    		 MMP Others
    MMP-2/MMP-9 Substrate (Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt) is a synthetic chromogenic polypeptide substrate whose core structure mimics the cleavage sites of MMP-2 and MMP-9 (gelatinase A and B) in collagen. After being hydrolyzed by collagenase, MMP-2/MMP-9 Substrate reacts with 4,4'-dithiodipyridine or Ellman's Reagent via its thiol fragment to produce a product with ultraviolet absorption properties .
    MMP-2/MMP-9 Substrate
  • HY-151661
    N3-L-Val-OH (CHA)

    L-azidovaline (CHA)

    		 ADC Linker Others
    N3-L-Val-OH (CHA) is a click chemistry containing an azide group, a valine derivative. N3-L-Val-OH (CHA) can also be used as a synthetic intermediate for Valaciclovir (Valacyclovir) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    N3-L-Val-OH (CHA)
  • HY-Y0689
    Thiocarbonyldiimidazole

    		MOFs Others
    Thiocarbonyldiimidazole is a synthetic chemical reagent that serves as a nitrogen-containing MOF ligand for synthetic applications. Thiocarbonyldiimidazole enables the preparation of thiocarbonyl imidazolides from alcohols, and is used in the Barton-McCombie deoxygenation reaction and natural product synthesis .
    Thiocarbonyldiimidazole
  • HY-W127342
    Decanoyl chloride

    Decanoic acid chloride

    		 Biochemical Assay Reagents Others
    Decanoyl chloride is an organic compound belonging to the class of acid chlorides. It is a colorless liquid with a pungent odor and is commonly used as a reagent in various organic chemical reactions, especially in the synthesis of esters, amides and fatty acids. Decanoyl chloride has numerous applications in synthetic organic chemistry, especially in the production of pharmaceuticals, agrochemicals and specialty chemicals. In addition, it can be used as a precursor for the synthesis of surfactants and detergents.
    Decanoyl chloride
  • HY-W095635
    Tetramethylammonium fluoride tetrahydrate

    		Biochemical Assay Reagents Others
    Tetramethylammonium fluoride tetrahydrate (TMAF) is a quaternary ammonium salt. TMAF is commonly used as a weak base and a source of fluoride ions in various organic reactions, including nucleophilic substitution, functional group deprotection, and ring-opening polymerization. Unlike other fluoride sources, TMAF is compatible with many functional groups, making it a versatile tool in synthetic chemistry. Functional reagents, In addition, TMAF has been used as a fluorinating agent in medicinal chemistry, for the preparation of radiotracers and protein modification in biochemistry, and the tetrahydrate form of TMAF is more stable and easier to handle than the anhydrous form.
    Tetramethylammonium fluoride tetrahydrate
  • HY-32149
    1-Bromo-3-iodobenzene

    		Biochemical Assay Reagents Drug Intermediate Others
    1-Bromo-3-iodobenzene is a biochemical reagent and an important organic synthetic intermediate. 1-Bromo-3-iodobenzene can be used for the synthesis of other active compounds .
    1-Bromo-3-iodobenzene
  • HY-W145053
    ChloraMine-T hydrate

    Sodium chloro(4-methylbenzenesulfonyl)azanide hydrate

    		 Factor Xa Bacterial Infection
    ChloraMine-T hydrate (Sodium chloro(4-methylbenzenesulfonyl)azanide (hydrate)) is a common reagent in various synthetic processes. It has been used as a reagent in aminohydroxylation and allylic amination reactions, a nitrogen source in aziridination reactions of alkenes and alkenes, and deprotection of sulfur groups in sulfur-containing compounds. It has been used as a reagent in the synthesis of factor Xa inhibitors. ChloraMine-T hydrate (Sodium chloro(4-methylbenzenesulfonyl)azanide (hydrate)) (0.2% w/v) is also an antimicrobial agent that kills Staphylococcus epidermidis, Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Proteus mirabilis, and Enterococcus cloacae.
    ChloraMine-T hydrate
  • HY-G0018S
    Norgestimate metabolite norelgestromin-d6

    17-Deacetyl norgestimate-d6; 17-Deacylnorgestimate-d6

    		 Isotope-Labeled Compounds Drug Metabolite Others
    Norgestimate metabolite norelgestromin-d6 is the deuterium labeled Norgestimate metabolite norelgestromin. Norelgestromin is a metabolite of Norgestimate, which is a progestin or synthetic progestogen. Norgestimate metabolite norelgestromin-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Norgestimate metabolite norelgestromin-d6
  • HY-32149S
    1-Bromo-3-iodobenzene-d4

    		Isotope-Labeled Compounds Biochemical Assay Reagents Drug Intermediate Others
    1-Bromo-3-iodobenzene-d4 is the deuterium labeled 1-Bromo-3-iodobenzene (HY-32149). 1-Bromo-3-iodobenzene is a biochemical reagent and an important organic synthetic intermediate. 1-Bromo-3-iodobenzene can be used for the synthesis of other active compounds .
    1-Bromo-3-iodobenzene-d4
  • HY-141520G
    ART558

    		DNA/RNA Synthesis Cancer
    ART558 (GMP) is ART558 (HY-141520) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. ART558 is a potent, selective and allosteric DNA polymerase theta (Polθ) inhibitor (IC50=7.9 nM). ART558 elicits BRCA-gene synthetic lethality and DNA damage. ART558 can be used for the research of cancer, such as breast cancer .
    ART558
  • HY-115715A
    EN219-alkyne

    		Fluorescent Dye Cancer
    EN219-alkyne is an alkyne-functionalized EN219 probe. EN219 (HY-P0287A) is a moderately selective synthetic covalent ligand against an N-terminal cysteine (C8) of RNF114 with an IC50 of 470 nM. EN219 inhibits RNF114-mediated autoubiquitination and p21 ubiquitination . EN219-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    EN219-alkyne
  • HY-W189421
    Diphenic anhydride

    DPA

    		 Biochemical Assay Reagents Others
    Diphenic anhydride (DPA) is a versatile reagent that can be used as a catalyst in many organic synthetic processes, such as polymer synthesis .
    Diphenic anhydride
  • HY-W097000
    1-Propanesulfonic acid sodium hydrate

    		Biochemical Assay Reagents Others
    1-Propanesulfonic acid (sodium hydrate) is a versatile biochemical reagent used in synthesis reagents, experimental buffer solutions, etc. 1-Propanesulfonic acid (sodium hydrate) is a kind of biological materials or organic compounds that are widely used in life science research .
    1-Propanesulfonic acid sodium hydrate
  • HY-136396
    Chlorempenthrin

    		Parasite Others
    Chlorempenthrin is a synthetic pyrethroid insecticide . Chlorempenthrin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Chlorempenthrin
  • HY-W724743
    Losartan azide

    		Biochemical Assay Reagents Cardiovascular Disease
    Losartan azide is a click chemistry reagent containing an azide group and is a synthetic intermediate for the preparation of angiotensin AT1R-targeted renal PET imaging probe [18 F]fluoropyridine-losartan .
    Losartan azide
  • HY-59125R
    (R,R)-(+)-Hydrobenzoin (Standard)

    		Endogenous Metabolite Reference Standards Others
    (R,R)-(+)-Hydrobenzoin (Standard) is the analytical standard of (R,R)-(+)-Hydrobenzoin. This product is intended for research and analytical applications. (R,R)-(+)-Hydrobenzoin is a chiral secondary alcohol that can be used as a key substrate or a chiral auxiliary reagent in various catalytic reactions and synthetic experiments.
    (R,R)-(+)-Hydrobenzoin (Standard)
  • HY-B0257S
    Levonorgestrel-d8

    D-Norgestrel-d8

    		 Isotope-Labeled Compounds Progesterone Receptor Endocrinology
    Levonorgestrel-d8 is the deuterium labeled Levonorgestrel. Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives . Levonorgestrel-d8 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Levonorgestrel-d8
  • HY-101405R
    Gestrinone (Standard)

    R 2323 (Standard)

    		 Reference Standards Estrogen Receptor/ERR Inflammation/Immunology
    Gestrinone (Standard) is the analytical standard of Gestrinone. This product is intended for research and analytical applications. Gestrinone (R2323) is a synthetic steroid hormone used to treat endometriosis. It inhibits leiomyoma cells with an IC50 of 43.67 μM. Gestrinone is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Gestrinone (Standard)
  • HY-139244S
    Norgestimate-d6

    		Isotope-Labeled Compounds Progesterone Receptor Endocrinology
    Norgestimate-d6 is the deuterium labeled Norgestimate. Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity. Norgestimate is used for an oral contraceptive . Norgestimate-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Norgestimate-d6
  • HY-114814A
    (+)-ORM-10921 free base

    		Adrenergic Receptor Others
    (+)-ORM-10921 Free base is a compound that exhibits significant biological activity, particularly in the context of chemical synthesis studies and the preparation of pyrido [1,2-b] isoquinoline derivatives. (+)-ORM-10921 Free base is utilized as an active reagent in multi-component reactions involving alkynes and isoquinolinium ylides. (+)-ORM-10921 Free base plays a crucial role in the advancement of synthetic organic chemistry by enabling the formation of complex molecular structures.
    (+)-ORM-10921 free base
  • HY-B0450AG
    Ciclopirox olamine

    Ciclopirox ethanolamine; HOE 296

    		 Bacterial Fungal Ferroptosis Infection
    Ciclopirox (olamine) (GMP) is Ciclopirox olamine (HY-B0450A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic .
    Ciclopirox olamine
  • HY-144585
    AGD-0182

    		Microtubule/Tubulin ADC Payload Others
    AGD-0182 is a microtubule disrupting agent. AGD-0182 is a synthetic analogue of the naturally occurring tubulin-binding molecule Dolastatin 10 . AGD-0182 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    AGD-0182
  • HY-W016618R
    Ethyl phenylglyoxylate (Standard)

    Ethyl benzoylformate (Standard); Phenylglyoxylic acid ethyl ester (Standard)

    		 Drug Intermediate Reference Standards Biochemical Assay Reagents Carboxylesterase (CES) Others
    Ethyl phenylglyoxylate (Ethyl benzoylformate) (Standard) is the analytical standard of Ethyl phenylglyoxylate (HY-W016618). This product is intended for research and analytical applications. Ethyl phenylglyoxylate (Ethyl benzoylformate), the ethyl ester of phenylglyoxylic acid, is used as a synthetic reagent. Ethyl phenylglyoxylate is also a poor substrate but a potent inhibitor of chicken liver carboxylesterase. Additionally, Ethyl phenylglyoxylate exhibits photoreactivity, where its excited triplet carbonyl can initiate intermolecular hydrogen abstraction, radical coupling and cross-linking reactions .
    Ethyl phenylglyoxylate (Standard)
  • HY-W701476
    Ethyl phenylglyoxylate-d5

    Ethyl benzoylformate-d5; Phenylglyoxylic acid ethyl ester-d5

    		 Isotope-Labeled Compounds Biochemical Assay Reagents Drug Intermediate Carboxylesterase (CES) Others
    Ethyl phenylglyoxylate-d5 (Ethyl benzoylformate-d5; Phenylglyoxylic acid ethyl ester-d5) is the deuterium labeled Ethyl phenylglyoxylate (HY-W016618). Ethyl phenylglyoxylate (Ethyl benzoylformate), the ethyl ester of phenylglyoxylic acid, is used as a synthetic reagent. Ethyl phenylglyoxylate is also a poor substrate but a potent inhibitor of chicken liver carboxylesterase. Additionally, Ethyl phenylglyoxylate exhibits photoreactivity, where its excited triplet carbonyl can initiate intermolecular hydrogen abstraction, radical coupling and cross-linking reactions .
    Ethyl phenylglyoxylate-d5
  • HY-B2091A
    Azidocillin sodium

    		Bacterial Antibiotic Infection
    Azidocillin sodium, a semi-synthetic Penicillin, is an orally active β-lactam antibiotic. Azidocillin sodium bears an azide functionality and retains on-target activity within bacteria. Azidocillin sodium can be used to research osteitis caused by dental surgery, otitis media, enterococcal septicemia and other bacterial infectious diseases . Azidocillin sodium is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Azidocillin sodium
  • HY-166863
    L-erythro-Sphingosine(synthetic)

    		Biochemical Assay Reagents Others
    L-erythro-Sphingosine(synthetic) is a biochemical assay reagent.
    L-erythro-Sphingosine(synthetic)
  • HY-79019
    N-Benzylsulfamide

    		Biochemical Assay Reagents Others
    N-Benzylsulfamide is a benzyl-substituted sulfamide reagent. N-Benzylsulfamide can be used as a synthetic precursor to generate dioxides of bicyclic thiadiazines .
    N-Benzylsulfamide
  • HY-18570C
    1-Naphthaleneacetic acid Sterile Solution (1 mg/ml)

    1-NAA Sterile Solution (1 mg/ml)

    		 Biochemical Assay Reagents Others
    1-Naphthaleneacetic acid Sterile Solution (1 mg/mL) is a ready-to-use synthetic plant growth regulator (Auxin) stock solution, a core reagent for regulating cell division, differentiation and growth in plant tissue culture.
    1-Naphthaleneacetic acid Sterile Solution (1 mg/ml)
  • HY-185226
    γ-Linolenic acid NHS ester

    		Drug Metabolite Cancer
    γ-Linolenic acid NHS ester is a lipid metabolite of γ-Linolenic acid (GLA) (HY-N7140), which can serve as a synthetic intermediate or probe labeling reagent for the preparation of GLA conjugates. In practical applications, γ-Linolenic acid NHS ester can be conjugated with taxanes and polysaccharides to form dual-type conjugates for drug delivery purposes .
    γ-Linolenic acid NHS ester
  • HY-108039R
    Bezisterim (Standard)

    HE 3286 (Standard); NE-3107 (Standard)

    		 Reference Standards NF-κB Neurological Disease Metabolic Disease Inflammation/Immunology
    Bezisterim (Standard) is the analytical standard of Bezisterim (HY-108039). This product is intended for research and analytical applications. Bezisterim (HE 3286; NE-3107) is a synthetic derivative of a natural anti-inflammatory steroid, β-AET. Bezisterim is an orally active partial NF-κB inhibitor. HE3286 reduces proinflammatory signals, including IL-6 and matrix metallopeptidase 3. Bezisterim freely penetrates the blood brain barrier in mice. Bezisterim can be used for the research of the ulcerative colitis, arthritis, experimental autoimmune encephalomyelitis . Bezisterim is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Bezisterim (Standard)
  • HY-145149S
    Duostatin 5-13C,d3

    		Isotope-Labeled Compounds ADC Payload Cancer
    Duostatin 5- 13C,d3 is the 13C-labeled Duostatin 5 (HY-145149). Duostatin 5 is a ADC Cytotoxin designed based on MMAF (HY-15579) and can be used to synthesize ADCs. The preparation of Duostatin 5 has the advantages of fewer synthetic steps, simple operation, less difficulty in quality control, and more stable chemical synthesis process. Duostatin 5 can be linked to the antibody targeting 5T4 (ZV05) by cross-linking with interchain cysteines through a disubstituted C-Lock linker. Duostatin 5 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups[1][2].
    Duostatin 5-13C,d3
  • HY-N0565AG
    Doxycycline (hydrochloride)

    		Apoptosis MMP Akt PI3K Infection Neurological Disease Inflammation/Immunology Cancer
    Doxycycline hydrochloride GMP is Doxycycline (hydrochloride) (HY-N0565A) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Doxycycline hydrochloride is an orally active highly lipophilic, tissue-permeable MMP inhibitor with broad-spectrum antibacterial activity. Doxycycline hydrochloride is also a semi-synthetic antibiotic with chelating properties, which blocks bacterial protein synthesis and inhibits extracellular matrix degradation through interactions with zinc and calcium atoms. Doxycycline hydrochloride also inhibits mitochondrial biogenesis, translation, and the expression of respiratory chain proteins. Doxycycline hydrochloride induces apoptosis, inhibits autophagy and EMT, downregulates stem cell markers, and activates the PI3K-AKT pathway, thereby effectively inhibiting the viability and proliferation of cancer cells such as breast cancer cells. Doxycycline hydrochloride also promotes the survival and self-renewal of embryonic stem cells and neural stem cells, and reduces the frequency of medium changes in culture. Doxycycline hydrochloride has been applied in studies related to breast cancer, prostate cancer, bladder cancer, and other cancers .
    Doxycycline (hydrochloride)

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