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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
36 Results for "
tetrahydroisoquinoline
" in MedChemExpress (MCE) Product Catalog:
Products (36)
36 Results for "tetrahydroisoquinoline" in MCE Product Catalog:
2
2 Cited Publications
Synonyms: Ecteinascidine 770; Et-770
Category:
Alkaloids Microorganisms Phenols Polyphenols Disease Research Fields Isoquinoline Alkaloids Cancer
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2
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1
Category:
Alkaloids Phenols Polyphenols Plants Lauraceae Isoquinoline Alkaloids Lindera aggregata (Sims) Kosterm.
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1 Cited Publications
Cat. No.: HY-W705106
CAS No.: 3422-42-2
Synonyms: (-)-(S)-Coclaurine hydrochloride; L-Coclaurine hydrochloride
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Cat. No.: HY-148480
CAS No.: 2728780-74-1
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Nrf2 activator-6, a tetrahydroisoquinoline compound, is a Nrf2 activator. Nrf2 activator-6 has an IC50 of 5 nM for inhibiting the Kelch domain-Nrf2 interaction (WO2021214470A1; Example 4) .
Cat. No.: HY-139570
CAS No.: 2248127-53-7
Synonyms: PM14
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Ecubectedin (PM14) is a derivative. Ecteinascidins is a family of tetrahydroisoquinoline alkaloids with wide range of antitumor and antimicrobial activities .
Cat. No.: HY-132828
CAS No.: 1639303-73-3
Synonyms: LT3001; DHDMIQK(KAP)
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Cardiovascular Disease Metabolic Disease Inflammation/Immunology
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Tetrahydropapaverine hydrochloride is a tetrahydroisoquinoline (TIQ) compound with inhibitory effects on tryptophan hydroxylase (TPH) (IC50 = 5.7 μM). Tetrahydropapaverine hydrochloride decreases intracellular serotonin content in murine mastocytoma P815 cells, with an IC50 value of 6.2 μM. Tetrahydropapaverine hydrochloride can be used for studies on potential neurotoxicity in monoaminergic neurons .
KRAS inhibitor-10 selectively and effectively inhibit RAS proteins, and particularly KRAS proteins. KRAS inhibitor-10 is an orally active anti-cancer agent and can be used for cancer research, such as pancreatic cancer, breast cancer, multiple myeloma, leukemia and lung cancer. KRAS inhibitor-10 is a tetrahydroisoquinoline compound (compound 11) extracted from patent WO2021005165 A1 .
Cat. No.: HY-N0137A
CAS No.: 54417-53-7
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(R)-Tetrahydropapaverine hydrochloride is the isomer of Tetrahydropapaverine hydrochloride (HY-N0137), and can be used as an experimental control. Tetrahydropapaverine hydrochloride is one of the Tetrahydroisoquinolines. Tetrahydropapaverine hydrochloride has neurotoxic effects on dopamine neurons .
Cat. No.: HY-60308A
CAS No.: 57196-62-0
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6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-W029659
CAS No.: 19716-56-4
Category:
Alkaloids Neurological Disease Endogenous metabolite Disease Research Fields Isoquinoline Alkaloids
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Cat. No.: HY-50936S
Synonyms: Ecteinascidin 743-d3; ET-743-d3
Cat. No.: HY-42318
CAS No.: 1870821-29-6
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(S)-4-(3-Bromophenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-113969
CAS No.: 61563-24-4
Category:
Alkaloids Neurological Disease Endogenous metabolite Disease Research Fields Isoquinoline Alkaloids
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Cat. No.: HY-I0422
CAS No.: 74163-81-8
Synonyms: L-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
Cat. No.: HY-178378
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G9a-IN-4 is a G9a inhibitor with high selectivity (IC50 = 32 nM). G9a-IN-4 shows high selectivity against the other tested lysine/arginine methyltransferases. G9a-IN-4 exhibits high enzymatic activity against G9a and more potent antiproliferative effects against all tested cancer cells. G9a-IN-4 significantly suppresses the H3K9me2 level. G9a-IN-4 triggers autophagy by inducing the production of ROS, thus leading to cell apoptosis and cell cycle arrest at G0/G1 in CT26 colon cells. G9a-IN-4 can be used for the study of colon cancer .
Cat. No.: HY-156079
CAS No.: 1071049-42-7
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Antidepressant agent 5 (Compound 3i) is a 7-substituted tetrahydroisoquinolines derivatives. Antidepressant agent 5 exhibits almost equal antidepressant activity compared with magnoflorine. ntidepressant agent 5 can be used for depressive disorder research .
Cat. No.: HY-139795
CAS No.: 1287261-04-4
ZYJ-25e is a potent histone deacetylase inhibitor (HDACi) with IC50s of 0.047 μM and 0.139 μM for HDAC6 and HDAC8, respectively. ZYJ-25e is a tetrahydroisoquinoline-bearing hydroxamic acid analogue. ZYJ-25e shows marked antitumor potency in the MDA-MB231 xenograft model .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
