L-Porretine
Based on 1 Customer Validation
L-Porretine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
For research use only. We do not sell to patients.
- CAS No.: 74163-81-8
- Formula: C10H11NO2
- Molecular Weight:177.20
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Platelet | IC50 |
0.452 μM
Compound: 2, IQ, THIQA
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Antiplatelet aggregatory activity in pig platelet poor plasma assessed as inhibition of arachidonic acid-induced platelet aggregation
Antiplatelet aggregatory activity in pig platelet poor plasma assessed as inhibition of arachidonic acid-induced platelet aggregation
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[PMID: 19729231] |
| Platelet | IC50 |
0.552 μM
Compound: 2, IQ, THIQA
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Antiplatelet aggregatory activity in pig platelet poor plasma assessed as inhibition of ADP-induced platelet aggregation
Antiplatelet aggregatory activity in pig platelet poor plasma assessed as inhibition of ADP-induced platelet aggregation
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[PMID: 19729231] |
| Platelet | IC50 |
0.881 μM
Compound: 2, IQ, THIQA
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Antiplatelet aggregatory activity in pig platelet poor plasma assessed as inhibition of thrombin-induced platelet aggregation
Antiplatelet aggregatory activity in pig platelet poor plasma assessed as inhibition of thrombin-induced platelet aggregation
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[PMID: 19729231] |
| Platelet | IC50 |
0.96 μM
Compound: 2, IQ, THIQA
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Antiplatelet aggregatory activity in pig platelet poor plasma assessed as inhibition of platelet-activating factor-induced platelet aggregation
Antiplatelet aggregatory activity in pig platelet poor plasma assessed as inhibition of platelet-activating factor-induced platelet aggregation
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[PMID: 19729231] |
| Platelet | IC50 |
452 nM
Compound: IQ
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Inhibition of platelet activating factor-induced pig platelet aggregation measured for 5 mins
Inhibition of platelet activating factor-induced pig platelet aggregation measured for 5 mins
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[PMID: 20122838] |
| Platelet | IC50 |
452.47 nM
Compound: 1,THIQA
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Inhibition of arachidonic acid-induced platelet aggregation in pig blood
Inhibition of arachidonic acid-induced platelet aggregation in pig blood
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[PMID: 18835178] |
| Platelet | IC50 |
481.4 nM
Compound: TIC, 1
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Antiplatelet activity against pig platelet assessed as inhibition of arachidonic acid-induced platelet aggregation by spectrophotometry
Antiplatelet activity against pig platelet assessed as inhibition of arachidonic acid-induced platelet aggregation by spectrophotometry
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[PMID: 21193315] |
| Platelet | IC50 |
541.7 nM
Compound: TIC, 1
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Antiplatelet activity against pig platelet assessed as inhibition of ADP-induced platelet aggregation by spectrophotometry
Antiplatelet activity against pig platelet assessed as inhibition of ADP-induced platelet aggregation by spectrophotometry
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[PMID: 21193315] |
| Platelet | IC50 |
552 nM
Compound: IQ
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Inhibition of adenosine diphosphate-induced pig platelet aggregation measured for 5 mins
Inhibition of adenosine diphosphate-induced pig platelet aggregation measured for 5 mins
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[PMID: 20122838] |
| Platelet | IC50 |
552.15 nM
Compound: 1,THIQA
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Inhibition of adenosine diphosphate-induced platelet aggregation in pig blood
Inhibition of adenosine diphosphate-induced platelet aggregation in pig blood
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[PMID: 18835178] |
| Platelet | IC50 |
881 nM
Compound: IQ
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Inhibition of thrombin-induced pig platelet aggregation measured for 5 mins
Inhibition of thrombin-induced pig platelet aggregation measured for 5 mins
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[PMID: 20122838] |
| Platelet | IC50 |
881.64 nM
Compound: 1,THIQA
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Inhibition of thrombin-induced platelet aggregation in pig blood
Inhibition of thrombin-induced platelet aggregation in pig blood
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[PMID: 18835178] |
| Platelet | IC50 |
943.8 nM
Compound: TIC, 1
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Antiplatelet activity against pig platelet assessed as inhibition of PAF-induced platelet aggregation by spectrophotometry
Antiplatelet activity against pig platelet assessed as inhibition of PAF-induced platelet aggregation by spectrophotometry
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[PMID: 21193315] |
| Platelet | IC50 |
960 nM
Compound: IQ
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Inhibition of arachidonic acid-induced pig platelet aggregation measured for 5 mins
Inhibition of arachidonic acid-induced pig platelet aggregation measured for 5 mins
|
[PMID: 20122838] |
| Platelet | IC50 |
960.18 nM
Compound: 1,THIQA
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Inhibition of platelet-activating factor-induced platelet aggregation in pig blood
Inhibition of platelet-activating factor-induced platelet aggregation in pig blood
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[PMID: 18835178] |
| Platelet | IC50 |
980.3 nM
Compound: TIC, 1
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Antiplatelet activity against pig platelet assessed as inhibition of thrombin-induced platelet aggregation by spectrophotometry
Antiplatelet activity against pig platelet assessed as inhibition of thrombin-induced platelet aggregation by spectrophotometry
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[PMID: 21193315] |
A constrained phenylalanine analog resisting enzymatic degradation.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 74163-81-8
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Appearance Solid
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Molecular Weight 177.20
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Formula C10H11NO2
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Color White to off-white
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SMILES
O=C([C@H]1NCC2=C(C=CC=C2)C1)O
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Synonyms
L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 3.33 mg/mL (18.79 mM; ultrasonic and adjust pH to 2 with 1M HCl)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (243 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.6433 mL | 28.2167 mL | 56.4334 mL | 141.0835 mL |
| 5 mM | 1.1287 mL | 5.6433 mL | 11.2867 mL | 28.2167 mL | |
| 10 mM | 0.5643 mL | 2.8217 mL | 5.6433 mL | 14.1084 mL | |
| 15 mM | 0.3762 mL | 1.8811 mL | 3.7622 mL | 9.4056 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
L-Porretine Related Classifications
HY-I0422 Related Classifications
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