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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
toggle-switch modulation
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "toggle-switch modulation" in MCE Product Catalog:
Art. -Nr.: HY-189717
CAS. Nr.: 2648548-71-2
Target:
Forschungsgebiete:
EA-RK-110 is a dopamine D3 receptor inverse agonist derived from Cariprazine (HY-14763) that stabilizes the inactive conformation and attenuates G protein signaling. EA-RK-110 weakly activates dopamine D2 receptor-mediated signaling. EA-RK-110 mediates inverse agonism through its meta-nitrile group via receptor residue interactions and toggle-switch modulation. EA-RK-110 can be used for research on dopamine receptor-related diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
