125 Results for "

tomography

" in MedChemExpress (MCE) Product Catalog:
Products (125)

125 Results for "tomography" in MCE Product Catalog:

5
Iohexol
Iohexol
0 Images
5 Cited Publications
Cat. No.: HY-B0594
CAS No.: 66108-95-0
Target:  

Autophagy Mitophagy

Research Areas:  

Cancer

Iohexol is a non-ionic, water-soluble contrast agent used as a reference marker for the determination of glomerular filtration rate (GFR) at the level of renal function. Iohexol can be used for contrast in myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging .
5
Pembrolizumab (anti-PD-1)
Pembrolizumab (anti-PD-1)
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5 Cited Publications
Cat. No.: HY-P9902A
Synonyms: MK-3475 (anti-PD-1); Lambrolizumab (anti-PD-1)

Target:  

PD-1/PD-L1

Research Areas:  

Cancer

Pembrolizumab (anti-PD-1) is a humanized IgG4 antibody and PD-1 inhibitor. Pembrolizumab produces PD-1 blockade, preventing PD-L1 and PD-L2 from connecting to PD-1. This avoids the uncontrolled regulation of T cells on cells that normally express PD-1 .
4
DOTATATE
DOTATATE
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4 Cited Publications
Cat. No.: HY-106244
CAS No.: 177943-88-3
Purity:  99.95%
Synonyms: Oxodotreotide
Target:  

Radionuclide-Drug Conjugates (RDCs)

Research Areas:  

Cancer

DOTATATE is a DOTA-conjugated peptide. DOTATATE can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT) . DOTATATE can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
4
DOTATATE acetate
DOTATATE acetate
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4 Cited Publications
Cat. No.: HY-106244A
CAS No.: 177943-89-4
Purity:  99.82%
Synonyms: Oxodotreotide acetate
Target:  

Radionuclide-Drug Conjugates (RDCs)

Research Areas:  

Cancer

DOTATATE acetate is a DOTA-conjugated peptide. DOTATATE acetate can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT) . DOTATATE (acetate) can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
2
T807
T807
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2 Cited Publications
Cat. No.: HY-101184
CAS No.: 1415379-56-4
Purity:  99.21%
Synonyms: AV-1451
Target:  

Tau Protein

Research Areas:  

Neurological Disease

T807 a novel tau positron emission tomography (PET) tracer.
2
2-Deoxy-2-fluoro-D-glucose
2-Deoxy-2-fluoro-D-glucose
0 Images
2 Cited Publications
Cat. No.: HY-141637
CAS No.: 29702-43-0
Purity:  99.89%
Synonyms: 2-Fluoro-2-deoxy-D-glucose; 2-Deoxy-2-fluoro-D-glucopyranose; Fluorodeoxyglucose
2-Deoxy-2-fluoro-D-glucose (2-Fluoro-2-deoxy-D-glucose) is a glucose analog that can be absorbed by cells. 2-Deoxy-2-fluoro-D-glucose is capable of being labelled with 18F for positron emission tomography (PET) imaging. 18F-2-Deoxy-2-fluoro-D-glucose can be used to detect breast cancer and gastric cancer .
2
Pentixafor
Pentixafor
0 Images
2 Cited Publications
Cat. No.: HY-153549
CAS No.: 1341207-62-2
Purity:  99.03%
Target:  

Radionuclide-Drug Conjugates (RDCs) CXCR

Research Areas:  

Others

Pentixafor is a peptide that targets CXCR4. Pentixafor is capable of being labelled with 68Gallium ( 68Ga) for positron emission tomography (PET) imaging . Pentixafor can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
2
Odapipam
Odapipam
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2 Cited Publications
Cat. No.: HY-129059
CAS No.: 131796-63-9
Purity:  99.00%
Synonyms: NNC 756
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

Odapipam (NNC 756) is a selective, high affinity and benzazepine dopamine D1 receptor antagonist with a Kd of 0.18 nM. Odapipam is also a superior positron emission tomography (PET) radiotracer .
1
DOTA-​NHS-ester
DOTA-​NHS-ester
0 Images
1 Cited Publications
Cat. No.: HY-128890
CAS No.: 170908-81-3
Purity:  ≥95.0%
Target:  

ADC Linkers

Research Areas:  

Cancer

DOTA-NHS-ester is a linker for affibody molecules and is applied in small animals PET, SPECT, and CT. DOTA-NHS-ester can be used to label radiotherapeutic agents or imaging probes for the detection of tumors .
1
PSMA-11
PSMA-11
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1 Cited Publications
Cat. No.: HY-125399
CAS No.: 1366302-52-4
Purity:  99.74%
Synonyms: HBED-CC-PSMA
Target:  

PSMA Radionuclide-Drug Conjugates (RDCs)

Research Areas:  

Cancer

PSMA-11 is a small molecule ligand that targets prostate-specific membrane antigen (PSMA) and has the ability to inhibit PSMA activity. PSMA-11 can be used to synthesize 68Ga-PSMA-11, a positron emission tomography (PET) tracer that can be used to image advanced prostate cancer .
1
DOTA-​NHS-ester TFA
DOTA-​NHS-ester TFA
0 Images
1 Cited Publications
Cat. No.: HY-128890B
Purity:  95.00%
Target:  

ADC Linkers Biochemical Assay Reagents

Research Areas:  

Cancer

DOTA-​NHS-ester (TFA) is used as a linker for affibody molecules, and it can be employed in small animal positron emission tomography (PET), single photon emission computed tomography (SPECT), and CT scanning. DOTA-​NHS-ester can be used to label radiotracers or imaging probes for tumor detection .
1
HG-10-102-01
HG-10-102-01
0 Images
1 Cited Publications
Cat. No.: HY-13488
CAS No.: 1351758-81-0
Purity:  99.55%
Target:  

LRRK2 MNK

Research Areas:  

Neurological Disease

HG-10-102-01 is a highly potent, selective, and brain-penetrable LRRK2 inhibitor, with IC50 values of 20.3 and 3.2 nM against wild-type LRRK2 and LRRK2[G2019S], respectively. HG-10-102-01 also inhibits MNK2 and MLK1, with IC50 values of 0.6 and 2.1 μM. HG-10-102-01 can be used for Parkinson's disease (PD) research .
DOTAGA-anhydride
DOTAGA-anhydride
0 Images
Cat. No.: HY-W087187
CAS No.: 1375475-53-8
Target:  

Radionuclide-Drug Conjugates (RDCs) Biochemical Assay Reagents

Research Areas:  

Infection Cancer

DOTAGA-anhydride is a DOTA-based metal chelator that can bind to radionuclides and is used to prepare radionuclide drug conjugates (RDCs). DOTAGA-anhydride has been successfully used for labeling antibodies (e.g., Trastuzumab (HY-P9907)). DOTAGA-anhydride can be used for the synthesis of a bimodal tag for Single-photon emission computed tomography (SPECT) or PET/optical imaging .
FAPI-74
FAPI-74
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Cat. No.: HY-147173
CAS No.: 2374782-76-8
Purity:  99.82%
Target:  

FAP

Research Areas:  

Cancer

FAPI-74 is a PET (positron emission tomography) tracer targeting the fibroblast activation protein (FAP). FAPI-74 can be used for FAP-positive tumor research .
AV-105
AV-105
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Cat. No.: HY-120947
CAS No.: 1205550-99-7
Purity:  99.70%
Target:  

Drug Intermediate

Research Areas:  

Neurological Disease

AV-105 is a Florbetapir ( 18F)-radiolabeled slyrylpyridine tosylate precursor extracted from patent WO2010078370A1, example 1.5. AV-105 can synthesize 18F-radiolabeled compounds, which are used for positron emission tomography (PET) imaging of neurodegenerative diseases of the brain .
(S)-p-SCN-Bn-DOTA
(S)-p-SCN-Bn-DOTA
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Cat. No.: HY-156038
CAS No.: 1020407-41-3
Purity:  99.75%
(S)-p-SCN-Bn-DOTA is a bifunctional chelator (BFC), a macrocyclic DOTA derivative for tumor pretargeting. (S)-p-SCN-Bn-DOTA can be used for the conjugation of peptides and radionuclides, such as as a linker for In-111 labeled radioimmunoconjugates (RICs) for single photon emission tomography (SPECT) and in vitro biodistribution studies .
N-Descyclopropanecarbaldehyde Olaparib
N-Descyclopropanecarbaldehyde Olaparib
0 Images
Cat. No.: HY-75706
CAS No.: 763111-47-3
Target:  

PARP Ligands for Target Protein for PROTAC

Research Areas:  

Cancer

N-Descyclopropanecarbaldehyde Olaparib is an analogue of Olaparib (HY-10162) containing DOTA moiety. N-Descyclopropanecarbaldehyde Olaparib is a PARP inhibitor used for synthesizing novel dual EGFR and PARP PROTAC, DP-C-4 (HY-141481) . N-Descyclopropanecarbaldehyde Olaparib can be radiolabeled with F-18 or fluorophore for positron emission tomography (PET) or optical imaging in several types of tumor .
PBR28
PBR28
0 Images
Cat. No.: HY-153248
CAS No.: 253307-65-2
Purity:  99.44%
Target:  

Biochemical Assay Reagents

Research Areas:  

Neurological Disease Inflammation/Immunology

PBR28 is a translocator protein (TSPO) binding positron emission tomography (PET) radiotracer with blood-brain barrier permeability . PBR28 binds to TSPO, a marker of microglial activation and neuroinflammation, and is used for neuroinflammation imaging in brain diseases and HIV-infected individuals .
JZP-MA-11
JZP-MA-11
0 Images
Cat. No.: HY-152148
CAS No.: 1672691-50-7
Purity:  99.26%
Target:  

MAGL

Research Areas:  

Neurological Disease

JZP-MA-11 is a brain-penetrant positron emission tomography (PET) ligand targeting the brain endocannabinoid α/β-hydrolase domain 6 (ABHD6) enzyme. JZP-MA-11 selectively inhibits ABHD6 with an IC50 value of 126 nM. [18F]JZP-MA-11 has the potential for preclinical evaluation targeting the brain ABHD6 in mice and nonhuman primate (NHP) .
Piflufolastat
Piflufolastat
0 Images
Cat. No.: HY-117756
CAS No.: 1423758-00-2
Purity:  99.10%
Synonyms: DCFPYL
Target:  

PSMA

Research Areas:  

Cancer

Piflufolastat (DCFPYL) can be used for the preparation of piflufolastat F 18 (DCFPyL F-18). Piflufolastat F-18 (DCFPyL F-18) is an 18F-labeled imaging agent. Piflufolastat F-18 can be used for positron emission tomography (PET) targeting prostate-specific membrane antigen (PSMA). Piflufolastat can be used for imaging of prostate cancer .
Assay Types