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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
triazole conjugates
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "triazole conjugates" in MCE Product Catalog:
Cat. No.: HY-174304
Target:
Research Areas:
Bis (vinylsulfonyl) piperazine-triazole-PEG3-O-diisopropylsilyl-triptolide is a drug-linker conjugates for ADC. Bis (vinylsulfonyl) piperazine-triazole-PEG3-O-diisopropylsilyl-triptolide consists of Triptolide (HY-32735) and a stable cleavable linker (Bis (vinylsulfonyl) piperazine-triazole-PEG3-O-diisopropylsilyl-Cl) (HY-174810). Bis (vinylsulfonyl) piperazine-triazole-PEG3-O-diisopropylsilyl-triptolide can be used for the synthesis of antibody-drug conjugates (ADCs) .
Cat. No.: HY-N7497
CAS No.: 20853-07-0
Target:
Cat. No.: HY-W800701
CAS No.: 2762752-63-4
Cat. No.: HY-174810
Target:
Research Areas:
Bis(vinylsulfonyl)piperazine-triazole-PEG3-O-diisopropylsilyl-Cl is a cleavable and silyl ether-based ADC linker that can be used in the synthesis of antibody-drug conjugates (ADC) .
Cat. No.: HY-155791
CAS No.: 2451934-98-6
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SMCC-NH-CH2-triazole-PEG8-oxydiacetamide-Lys(MTT)-PAB (Page 7, Compound C) is an ADC linker that can be used for the synthesis of antibody-conjugated active molecules (ADC) .
Cat. No.: HY-163789
Cat. No.: HY-W586475
Research Areas:
Fluorescein-triazole-PEG5-DOTA is a radionuclide conjugate (RDC), which is capable of binding to a radionuclide. RDC has the ability to specifically target biomolecules and can be used in medical imaging or therapy .
Cat. No.: HY-N7497R
CAS No.: 20853-07-0
Category:
Target:
Cat. No.: HY-W800702
CAS No.: 2770422-53-0
Cat. No.: HY-D3574
Target:
Research Areas:
AF488 Picolyl Azide is a Fluorescent dye designed for bioorthogonal visualization applications. AF488 Picolyl Azide functions via copper (I)-catalyzed azide-alkyne cycloaddition click chemistry, where its azide group undergoes covalent reaction with alkyne-functionalized molecules to form fluorescent triazole conjugates. AF488 Picolyl Azide enables the visualization of metabolically labeled isoprenoids in bacteria, which localize to the cell membrane and division septum .
Cat. No.: HY-169368
CAS No.: 2412988-59-9
Research Areas:
Thalidomide-O-Triazole-C4-amino is an E3 ligase ligand-linker conjugate. Thalidomide-O-Triazole-C4-amino can be used to synthesize aTAG 4531 (HY-163168) .
Cat. No.: HY-181058
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Research Areas:
Cyclopamine-COO-2-ethoxy-1,3-benzodioxole-O-C-Triazole-C5-AC is a drug-linker conjugate, with Cyclopamine (HY-17024) as its drug moiety. Cyclopamine-COO-2-ethoxy-1,3-benzodioxole-O-C-Triazole-C5-AC itself exhibits no significant anti-tumor activity. Cyclopamine-COO-2-ethoxy-1,3-benzodioxole-O-C-Triazole-C5-AC can be used for the synthesis of ADC molecules .
Cat. No.: HY-D3521
CAS No.: 1807503-82-7
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Research Areas:
Coumarin 343 azide is a fluorescent dye used for the fluorescent labeling of alkyne-containing biomolecules based on click chemistry. Its detection mechanism relies on the copper (I)-catalyzed azide-alkyne cycloaddition (CuAAC), a type of click reaction: under mild aqueous conditions, the azide group of this dye selectively reacts with the alkyne moiety of propargyl geldanamycin to form a triazole bond that conjugates the fluorescent dye to the target biomolecule; fluorescence is generated upon successful conjugation to the target .
Cat. No.: HY-185423
Research Areas:
PreQ1-DBCO is a strained cyclooctyne commonly used in click chemistry. PreQ1-DBCO undergoes TGT-catalyzed guanine base exchange in DNA oligonucleotide stem-loops to replace guanine. PreQ1-DBCO functionalizes custom DNA oligonucleotide sequences. DBCO-modified DNA oligonucleotides are conjugated with azide peptides via strain-promoted azide-alkyne click chemistry (SPAAC). PreQ1-DBCO can be used in studies of hemophilia B (Christmas disease) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
