72 Results for "

tumor-associated antigen

" in MedChemExpress (MCE) Product Catalog:
Products (72)

72 Results for "tumor-associated antigen" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P70457
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TACSTD2; Epithelial Glycoprotein-1; Prev. M1S1; Membrane Component, Chromosome 1, Surface Marker 1; GA733-1; Gastrointestinal tumor-associated antigen GA7331; TROP2; Pancreatic Carcinoma Marker Protein GA7331; tumor-associated Calcium Signal Transducer 2; Cell Surface Glycoprotein TROP2; EGP-1; Truncated TACSTD2; Membrane Component Chromosome 1 Surface Marker 1; GA7331; Pancreatic Carcinoma Marker Protein GA733-1; EGP1; Trophoblast Cell Surface antigen 2; GP50; Cell Surface Glycoprotein Trop-2; tumor associated Calcium Signal Transducer 2; 40kD Glycoprotein, Identified By Monoclonal Antibody GA733
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P99276
CAS No.: 792921-10-9
Synonyms: Anti-Human CA-125 Recombinant Antibody

Research Areas:  

Cancer

Abagovomab (Anti-Human CA-125 Recombinant Antibody) is a mouse monoclonal anti-idiotypic antibody that targets the tumor-associated antigen CA-125 (binding affinity: 0.5 nM). Produced by mouse hybridoma cells, Abagovomab mimics human TAA, CA-125. Abagovomab also induces humoral and cellular immune responses against ovarian cancer (oc) .
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1
1 Cited Publications
Cat. No.: HY-P99236
CAS No.: 2259301-27-2
Synonyms: FP-1305
Bexmarilimab (FP-1305) is a potent humanized anti-CLEVER-1 IgG4 antibody with an IC50 value of 4.51 nM. Bexmarilimab is capable of inducing a phenotypic M2 to M1 immune switch of tumor-associated macrophages. Bexmarilimab can promote antigen presentation and pro-inflammatory cytokine secretion. Bexmarilimab can induce B-cell and T-cell activation. Bexmarilimab can be used in researches of immunology and cancer, such as colorectal carcinoma .
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1
1 Cited Publications
Cat. No.: HY-W854385A
Synonyms: SLeA sodium
Research Areas:  

Cancer

Sialyl Lewis A (SLeA) sodium is a tumor-associated carbohydrate antigen, also known as carbohydrate antigen 19-9 (CA19-9), that binds to E-selectin (ELAM-1) and selectins to mediate cell-endothelium adhesion. Sialyl Lewis A sodium promotes cancer cell-vascular endothelium adhesion, and its surface presence correlates with increased tumorigenicity and invasiveness in cancer cells. Sialyl Lewis A sodium shows elevated expression in human adenocarcinomas of the colon, pancreas, and stomach, with expression levels linked to tumor progression and poor prognosis in colorectal and gastric carcinomas. Sialyl Lewis A sodium can be used for the research of cancers, such as colon, pancreas, stomach, and squamous lung cancer .
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1
1 Cited Publications
Cat. No.: HY-P704276
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TACSTD2; Epithelial Glycoprotein-1; Prev. M1S1; Membrane Component, Chromosome 1, Surface Marker 1; GA733-1; Gastrointestinal tumor-associated antigen GA7331; TROP2; Pancreatic Carcinoma Marker Protein GA7331; tumor-associated Calcium Signal Transducer 2
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-165740
CAS No.: 65988-71-8
Synonyms: Disialoganglioside GD2
Target:  

Apoptosis

Research Areas:  

Cancer

Ganglioside GD2 (Disialoganglioside GD2) is a tumor-associated antigen. Ganglioside GD2 shows limited expression in normal tissues but is overexpressed in multiple tumor types, and thus can serve as a target in cancer. Ganglioside GD2 is associated with tumor development and malignant phenotypes, and its mechanism of action relies on enhancing cell proliferation, motility, migration, adhesion and invasion, with specific effects depending on the tumor type .
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Cat. No.: HY-P1827
CAS No.: 219312-69-3
Target:  

Tyrosinase MHC

Research Areas:  

Cancer

mTRP-2 (180-188) is an MHC class I-restricted tumor-associated antigenic peptide derived from mouse tyrosinase-related protein 2 (TRP-2). mTRP-2 (180-188) binds to HLA-A*0201 with an ID50 of 36 nM. mTRP-2 (180-188) can be presented by H-2K b molecules and activate TRP-2-specific cytotoxic T lymphocytes (CTL). mTRP-2 (180-188) induces immune responses against B16 melanoma by promoting antigen-specific T cell proliferation, cytokine release, and CTL-mediated tumor cell killing. mTRP-2 (180-188) can be used in studies related to melanoma, glioma, and tumor immunology .
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Cat. No.: HY-P99436
CAS No.: 1370261-50-9
Synonyms: ABR-214936
Anatumomab mafenatox (ABR-214936) is a 73 KDa recombinant protein to recognize the tumor-associated antigen 5T4, which is widely expressing in malignancy. Anatumomab mafenatox is between a modified form of SEA and a murine Fab. The main side effects of Anatumomab mafenatox are reported to include fever, low blood pressure, pain, nausea and drowsiness .
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Cat. No.: HY-W854385
CAS No.: 92448-22-1
Synonyms: SLeA
Research Areas:  

Cancer

Sialyl Lewis A (SLeA) is a tumor-associated carbohydrate antigen, also known as carbohydrate antigen 19-9 (CA19-9), that binds to E-selectin (ELAM-1) and selectins to mediate cell-endothelium adhesion. Sialyl Lewis A promotes cancer cell-vascular endothelium adhesion, and its surface presence correlates with increased tumorigenicity and invasiveness in cancer cells. Sialyl Lewis A shows elevated expression in human adenocarcinomas of the colon, pancreas, and stomach, with expression levels linked to tumor progression and poor prognosis in colorectal and gastric carcinomas. Sialyl Lewis A can be used for the research of cancers, such as colon, pancreas, stomach, and squamous lung cancer .
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Cat. No.: HY-P10947
Research Areas:  

Cancer

MACTIDE-V is an orally active and selective peptide-drug conjugate targeting CD206. MACTIDE-V delivers Verteporfin (HY-B0146) to CD206 + tumor-associated macrophages (TAM) to inhibit the YAP/TAZ signaling pathway, prompting YAP exclusion from the nucleus, inducing TAM polarization toward an anti-tumoral phenotype with enhanced phagocytosis and antigen presentation, and boosting T cell infiltration and NK cell activity. MACTIDE-V suppresses primary tumor growth and lung metastasis in triple-negative breast cancer (TNBC) mouse models .
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Cat. No.: HY-157288
Research Areas:  

Metabolic Disease

(R)-Phe-A110/B319, a hapten, is a selective binder to tumor-associated antigens. (R)-Phe-A110/B319 has a 20-fold higher affinity towards the H1047R mutant of p110α in the p110α/p85α PI3K complex. (R)-Phe-A110/B319 can be used for the research of conditional chimeric antigen receptor T (CAR-T) cell activation and tumor targeting .
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Cat. No.: HY-P991903

Target:  

CD20

Research Areas:  

Cancer

PSB102 is a humanized Fc-enhanced IgG1 monoclonal antibody directed against the human B-cell-specific cell surface antigen and tumor-associated antigen CD20 .
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Cat. No.: HY-P10607
CAS No.: 610268-80-9
Target:  

EBV

Research Areas:  

Cancer

IALYLQQNW is a specific nonapeptide sequence derived from the tumor-associated antigen latent membrane protein 1 (LMP1) encoded by Epstein-Barr virus (EBV). As a latent T-cell epitope, IALYLQQNW is able to activate EBV-specific cytotoxic T lymphocytes (CTLs), which are able to recognize and kill EBV-infected cells expressing LMP1. IALYLQQNW plays an important role in the immune response against EBV-associated tumors and can be used in the study of Hodgkin's disease and nasopharyngeal carcinoma .
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Cat. No.: HY-P5930
Synonyms: MDM2 32-46
Target:  

Ligands for E3 Ligase

Research Areas:  

Cancer

HOXB7 8–25 (MDM2 32-46) is an MDM2-derived peptide epitope and can elicit antigen-specifc and tumor-reactive CD4 + T cell responses .
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Cat. No.: HY-P811986
Synonyms: UBXN11; UBX Domain Protein 11; SOC; Socius; UBXD5; SOCI; Colorectal tumor-associated antigen COA-1; UBX Domain-Containing Protein 11; UBX Domain-Containing Protein 5; Colorectal tumor-associated antigen-1; UBX Domain Containing 5; PP2243; COA-1

Host:  

Mouse

Application:  

WB

Reactivity:  

Human

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Cat. No.: HY-P811986A
Synonyms: UBXN11; UBX Domain Protein 11; SOC; Socius; UBXD5; SOCI; Colorectal tumor-associated antigen COA-1; UBX Domain-Containing Protein 11; UBX Domain-Containing Protein 5; Colorectal tumor-associated antigen-1; UBX Domain Containing 5; PP2243; COA-1

Host:  

Mouse

Application:  

WB

Reactivity:  

Human

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Cat. No.: HY-P71387
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TACSTD2; Epithelial Glycoprotein-1; Prev. M1S1; Membrane Component, Chromosome 1, Surface Marker 1; GA733-1; Gastrointestinal tumor-associated antigen GA7331; TROP2; Pancreatic Carcinoma Marker Protein GA7331; tumor-associated Calcium Signal Transducer 2
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P72015
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TACSTD2; Epithelial Glycoprotein-1; Prev. M1S1; Membrane Component, Chromosome 1, Surface Marker 1; GA733-1; Gastrointestinal tumor-associated antigen GA7331; TROP2; Pancreatic Carcinoma Marker Protein GA7331; tumor-associated Calcium Signal Transducer 2
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P74488
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TACSTD2; Epithelial Glycoprotein-1; Prev. M1S1; Membrane Component, Chromosome 1, Surface Marker 1; GA733-1; Gastrointestinal tumor-associated antigen GA7331; TROP2; Pancreatic Carcinoma Marker Protein GA7331; tumor-associated Calcium Signal Transducer 2
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P77861
Purity:  ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: TACSTD2; Epithelial Glycoprotein-1; Prev. M1S1; Membrane Component, Chromosome 1, Surface Marker 1; GA733-1; Gastrointestinal tumor-associated antigen GA7331; TROP2; Pancreatic Carcinoma Marker Protein GA7331; tumor-associated Calcium Signal Transducer 2
Species:  
Cynomolgus
Source:  
HEK293
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