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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
vascular dementia
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "vascular dementia" in MCE Product Catalog:
5
5 Cited Publications
Target:
Research Areas:
PI3K/Akt/CREB activator 1 (compound AE-18) is a potent, orally active PI3K/Akt/CREB activator. PI3K/Akt/CREB activator 1 promotes neuronal proliferation, induced differentiation of Neuro-2a cells into a neuron-like morphology, and accelerated the establishment of axon-dendrite polarization of primary hippocampal neurons through upregulating brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway. PI3K/Akt/CREB activator 1 can be used in research of vascular dementia (VaD) .
2
2 Cited Publications
Synonyms: Breviscapinun
Category:
1
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
Ozagrel (OKY-046) is a high selective and orally active thromboxane A2 (TXA2) synthase inhibitor with an IC50 of 11 nM. Ozagrel exerts anti-platelet aggregation, vasodilation and anti-inflammatory effects by inhibiting the production of TXA2 and increasing the production of prostacyclin (PGI2). Ozagrel can be used for the study of ischemic stroke, asthma and thromboembolic diseases .
1
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
Ozagrel hydrochloride (OKY-046 hydrochloride) is a high selective and orally active thromboxane A2 (TXA2) synthase inhibitor with an IC50 of 11 nM. Ozagrel hydrochloride exerts anti-platelet aggregation, vasodilation and anti-inflammatory effects by inhibiting the production of TXA2 and increasing the production of prostacyclin (PGI2). Ozagrel hydrochloride can be used for the study of ischemic stroke, asthma and thromboembolic diseases .
Cat. No.: HY-N4246
CAS No.: 382148-47-2
Cat. No.: HY-N7699C
CAS No.: 183668-50-0
Category:
Polysaccharides Microorganisms Neurological Disease Marine algae Marine natural products Disease Research Fields Saccharides
Target:
Cat. No.: HY-P10887
CAS No.: 2988012-71-9
Synonyms: AV-001
Target:
Tie ANGPTL SARS-CoV Aquaporin TNF Receptor PAI-1 CXCR P-selectin
Research Areas:
Cat. No.: HY-146765
CAS No.: 3019885-78-7
Target:
Research Areas:
AMS-17 is a potent NLRP3 inhibitor, inhibiting microglia activation in vitro and in vivo. AMS-17 also inhibits cytokines such as caspase-1, TNF-α, IL-1β and inducible nitric oxide synthase (iNOS) in N9 cells. AMS-17 can be used for researching inflammation-associated neurological disorders, such as vascular dementia (VaD) .
Synonyms: HWA 285
Research Areas:
Propentofylline (HWA 285) is an orally active and brain-penetrant phosphodiesterase inhibitor. Propentofylline blocks adenosine reuptake and prevents cyclic nucleotide degradation. Propentofylline can be used for the research of primary degenerative (Alzheimer's) dementia, vascular dementia, cerebral ischemia, acute stroke, and learning and memory disorders .
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GluN2B-NMDAR antagonist-1 is an orally active GluN2B-NMDAR antagonist. GluN2B-NMDAR antagonist-1 has neuroprotective activity. GluN2B-NMDAR antagonist-1 can be used for research of ischemic injury .
Cat. No.: HY-N7699B
CAS No.: 149511-34-2
Category:
other families Polysaccharides Neurological Disease Marine algae Marine natural products Plants Disease Research Fields Saccharides
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Cat. No.: HY-N7699F
CAS No.: 862694-98-2
Category:
Polysaccharides Microorganisms Neurological Disease Marine algae Marine natural products Disease Research Fields Saccharides
Target:
Cat. No.: HY-113745
CAS No.: 914808-66-5
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Research Areas:
LX-6171 is an orally active SLC6A7 inhibitor. LX-6171 can be used to study diseases characterized by cognitive impairment, such as Alzheimer's disease, schizophrenia or vascular dementia .
Cat. No.: HY-177282
CAS No.: 524743-70-2
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
SST1 receptor antagonist-2 (Example 2) is a piperazine derivative and a somatostatin receptor 1 (SST1) antagonist. SST1 receptor antagonist-2 can be used in the research of psychiatric diseases, neurodegenerative diseases, tumors, as well as vascular disorders and immunological diseases .
Cat. No.: HY-N7699A
CAS No.: 66754-13-0
Category:
Target:
Cat. No.: HY-N7699D
CAS No.: 183668-52-2
Category:
Polysaccharides Microorganisms Neurological Disease Marine algae Marine natural products Disease Research Fields Saccharides
Target:
Cat. No.: HY-N7699E
CAS No.: 862694-97-1
Category:
Polysaccharides Microorganisms Neurological Disease Marine algae Marine natural products Disease Research Fields Saccharides
Target:
Cat. No.: HY-N7699G
CAS No.: 862694-99-3
Category:
Polysaccharides Microorganisms Neurological Disease Marine algae Marine natural products Disease Research Fields Saccharides
Target:
Cat. No.: HY-101669
CAS No.: 134069-68-4
Target:
Research Areas:
TDN345 is a Ca 2+ antagonist, used for the treatment of vascular and senile dementia including Alzheimer's disease.
Cat. No.: HY-107203S
CAS No.: 1216516-37-8
Synonyms: HWA 285-d6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
