- Natural Products
- Plants
- Scrophulariaceae
- Bacopa monnieri (Linn.) Wettst.
Bacopa monnieri (Linn.) Wettst.
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Bacopa monnieri (Linn.) Wettst. (20)
- 1
- Formula: C47H76O18
- Molecular Weight: 929.10
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- Formula: C47H76O18
- Molecular Weight: 929.10
Bacoside A3 is a triterpenoid saponin isolated from Bacopa monnieri. Bacoside A3 has neuroprotective activity, downregulating β-amyloid-induced inflammatory responses and inhibiting neuronal apoptosis. Bacoside A3 can be used in the study of Alzheimer's disease.
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- Formula: C46H74O17
- Molecular Weight: 899.07
Bacopaside X is found in Bacopa monnieri, and shows a binding affinity toward the D1 receptor.
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- Formula: C46H74O17
- Molecular Weight: 899.07
Bacopasaponin C is an orally active natural glycoside. Bacopasaponin C can be isolated from Bacopa monniera. Bacopasaponin C inhibits Verapamil (HY-14275)-stimulated P-gp ATPase activity with an IC50 of 57.83 μg/mL. Bacopasaponin C has antitumor activity against sarcomas. Bacopasaponin C has antiparasitic activity against Leishmania donovani.
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- Formula: C46H74O20S
- Molecular Weight: 979.13
Bacopaside I is an orally active aquaporin AQP1 inhibitor and PKC modulator with neuroprotective and anticancer activities. Bacopaside I specifically blocks the water channel and cGMP-gated ion channel activities of AQP1 without affecting AQP4, thereby inhibiting the migration of colon cancer cells expressing AQP1. Bacopaside I activates the Akt pathway by interacting with PI3K, specifically inhibits MAO-A, effectively alleviates neuron necrosis and apoptosis induced by oxygen-glucose deprivation, reduces oxidative stress, and regulates the surface expression of neuroreceptors. When combined with Bacopaside II (HY-N6016), Bacopaside I significantly reduces the viability, proliferation and invasion ability of breast cancer cells, and binds to the pregnane X receptor (PXR). Bacopaside I is applicable to the research of colon cancer, breast cancer, vascular dementia, cerebral ischemia and other related diseases.
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- Formula: C47H76O18
- Molecular Weight: 929.10
Bacoside A3 (Standard) is the analytical standard of Bacoside A3. This product is intended for research and analytical applications. Bacoside A3, a triterpenoid saponin, is one of the major active constituents in Bacopa monnieri. Bacoside A3 has neuroprotective activity.
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- Formula: C19H22O
- Molecular Weight: 266.38
1,7-Diphenyl-6 (E)-hepten-3-ol is a diarylheptane compound that can be isolated from Curcuma comosa. 1,7-Diphenyl-6 (E)-hepten-3-ol effectively inhibits the motility of Caenorhabditis elegans, thereby causing paralysis or death of the nematodes as a nematicide. 1,7-Diphenyl-6 (E)-hepten-3-ol can be used in studies related to nematode infections.
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- Formula: C41H68O13
- Molecular Weight: 768.97
Bacoside A is an orally active, blood-brain barrier-permeable triterpenoid saponin that modulates the activities of ATPases, AChE, CaMK2A and iNOS. Derived from Bacopa monniera. Bacoside A exerts significant antioxidant, anti-inflammatory and anti-apoptotic effects by maintaining ion balance, scavenging reactive oxygen species, stabilizing cell membranes, and regulating the expression of NF-κB and apoptosis-related proteins. Bacoside A counteracts morphine-induced reductions in Na+/K+-ATPase, Ca2+-ATPase and Mg2+-ATPase activities, increases mitochondrial membrane potential, and decreases intracellular reactive oxygen species levels. Bacoside A specifically binds to calcium/calmodulin-dependent protein kinase IIA to trigger endoplasmic reticulum calcium release. Bacoside A exhibits non-apoptotic cytotoxicity against glioblastoma cells while protecting normal nerve cells from stress-induced damage. Bacoside A is applicable to the research of Parkinson's disease and glioblastoma multiforme.
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- Formula: C41H66O16S
- Molecular Weight: 847.02
Bacopaside VI is a Bacopaside. Bacopaside VI can be isolated from Bacopa monnieri.
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- Formula: C47H76O18
- Molecular Weight: 929.10
Bacopaside II (Standard) is the analytical standard of Bacopaside II. This product is intended for research and analytical applications. Bacopaside II, an extract from the medicinal herb Bacopa monnieri, blocks the Aquaporin-1 (AQP1) water channel and impairs migration of cells that express AQP1. Bacopaside II induces cell cycle arrest and apoptosis.
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- Formula: C46H74O20S
- Molecular Weight: 979.13
Bacopaside I (Standard) is the analytical standard of Bacopaside I. This product is intended for research and analytical applications. Bacopaside I is an orally active aquaporin AQP1 inhibitor and PKC modulator with neuroprotective and anticancer activities. Bacopaside I specifically blocks the water channel and cGMP-gated ion channel activities of AQP1 without affecting AQP4, thereby inhibiting the migration of colon cancer cells expressing AQP1. Bacopaside I activates the Akt pathway by interacting with PI3K, specifically inhibits MAO-A, effectively alleviates neuron necrosis and apoptosis induced by oxygen-glucose deprivation, reduces oxidative stress, and regulates the surface expression of neuroreceptors. When combined with Bacopaside II (HY-N6016), Bacopaside I significantly reduces the viability, proliferation and invasion ability of breast cancer cells, and binds to the pregnane X receptor (PXR). Bacopaside I is applicable to the research of colon cancer, breast cancer, vascular dementia, cerebral ischemia and other related diseases.
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- Formula: C46H74O17
- Molecular Weight: 899.07
Bacopasaponin C (Standard) is the analytical standard of Bacopasaponin C (HY-N6015). This product is intended for research and analytical applications. Bacopasaponin C is an orally active natural glycoside. Bacopasaponin C can be isolated from Bacopa monniera. Bacopasaponin C inhibits Verapamil (HY-14275)-stimulated P-gp ATPase activity with an IC50 of 57.83 μg/mL. Bacopasaponin C has antitumor activity against sarcomas. Bacopasaponin C has antiparasitic activity against Leishmania donovani.
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- Formula: C46H74O17
- Molecular Weight: 899.07
Bacoside A2 is a triterpenoid saponin.
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- Formula: C42H68O14
- Molecular Weight: 796.98
Bacopaside N1 is a diglycosidic saponin.
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- Formula: C41H66O13
- Molecular Weight: 766.95
Bacopaside IV is a saponin.
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- Formula: C42H68O14
- Molecular Weight: 796.98
Bacopaside N2 is a diglycosidic saponin.
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- Formula: C41H66O13
- Molecular Weight: 766.95
Bacopaside V is a bioactive triterpenoid glycoside of Bacopa monniera, a herb having confirmed nervine tonic activity.
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- Formula: C30H48O3
- Molecular Weight: 456.70
Bacosine is a Triterpenoids product that can be isolated from the herbs of Bacopa monnieri.
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- Formula: C₄₆H₇₄O₁₇
- Molecular Weight: 899.07
Bacopaside X (Standard) is the analytical standard of Bacopaside X. This product is intended for research and analytical applications. Bacopaside X is found in Bacopa monnieri, and shows a binding affinity toward the D1 receptor.
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