Thalidomide-5-NH-PEG3-NH2 hydrochloride
Thalidomide-5-NH-PEG3-NH2 hydrochloride is a Thalidomide (HY-14658)-based cereblon ligand that recruits CRBN proteins. Thalidomide-5-NH-PEG3-NH2 hydrochloride can be connected to the target protein ligand through a linker to form a PROTAC molecule. For example, THAL-SNS-032 (HY-123937).
For research use only. We do not sell to patients.
- CAS No.: 2863635-01-0
- Formula: C21H29ClN4O7
- Molecular Weight:484.93
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
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Cereblon |
Chemical Information
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CAS No. 2863635-01-0
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Appearance Solid
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Molecular Weight 484.93
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Formula C21H29ClN4O7
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Color Light yellow to yellow
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SMILES
O=C1NC(C(CC1)N2C(C3=CC=C(NCCOCCOCCOCCN)C=C3C2=O)=O)=O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Purity & Documentation
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Data Sheet (264 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Thalidomide-5-NH-PEG3-NH2 hydrochloride Related Classifications
HY-156165 Related Classifications
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