TNF-α agonistic 1
Based on 1 Customer Validation
TNF-α agonistic 1 (compound 22a) can repolarize tumor-associated macrophages (TAMs) in the tumor microenvironment (TME) from the M2 phenotype to the M1 anti-tumor phenotype.
For research use only. We do not sell to patients.
- Purity: 98.37%
- CAS No.: 2379727-88-3
- Formula: C24H21ClF3N5O
- Molecular Weight:487.90
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 2379727-88-3
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Appearance Solid
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Molecular Weight 487.90
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Formula C24H21ClF3N5O
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Color Light yellow to light brown
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SMILES
O=C(NC1CC2=C(CC1)NC3=CC(C4=CN(C)N=C4)=CC=C23)NC5=CC=C(C(C(F)(F)F)=C5)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)