Trichodermamide C
Trichodermamide C, dipeptide, is a metabolite of Eupenicillium sp.. Trichodermamide C can induce cells apoptosis. Trichodermamide C can be used for research of colon cancer.
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- CAS No.: 1036712-09-0
- 화학식: C21H22N2O9
- 분자량:446.41
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Endogenous Metabolite Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
4.28 μg/mL
Compound: trichodermamide C, 1
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Cytotoxicity against human A549 cells after 24 hrs
Cytotoxicity against human A549 cells after 24 hrs
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[PMID: 18424045] |
| HCT-116 | IC50 |
0.68 μg/mL
Compound: trichodermamide C, 1
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Cytotoxicity against human HCT116 cells after 24 hrs
Cytotoxicity against human HCT116 cells after 24 hrs
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[PMID: 18424045] |
| HeLa | IC50 |
>10 μM
Compound: 3
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Cytotoxicity against human HeLa cells after 48 hrs by SRB assay
Cytotoxicity against human HeLa cells after 48 hrs by SRB assay
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[PMID: 28051860] |
Trichodermamide C displays cytotoxicity towards the human colorectal carcinoma HCT116 and human lung carcinoma A549 with IC50 values of 0.68 and 4.28 μg/ml, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1036712-09-0
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분자량 446.41
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화학식 C21H22N2O9
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SMILES
O[C@]12[C@](ON=C(C2)C(N(C3=CC4=CC=C(OC)C(OC)=C4OC3=O)C)=O)([H])[C@@H](C=C[C@H]1O)O
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Structure Classification
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Initial Source
Eupenicillium sp.
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)