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Cat. No.: HY-FL12053A

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Vinorelbine tartrate solution

Name: Vinorelbine tartrate solution
Brand: MedChemExpress
SKU: HY-FL12053A
Availability: PreOrder

(Synonyms: KW-2307 solution; Nor-5'-anhydrovinblastine ditartrate solution)

Vinorelbine tartrate solution is mainly composed of Vinorelbine ditartrate (HY-12053A). Vinorelbine (ditartrate) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC₅₀ of 1.25 nM.

For research use only. We do not sell to patients.

CAS No.: 125317-39-7
Formula: C₅₃H₆₆N₄O₂₀
Molecular Weight:1079.11

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Vinorelbine tartrate solution Chemical Structure

CAS No.: 125317-39-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

Chemical Information

CAS No. 125317-39-7
Molecular Weight 1079.11
Formula C₅₃H₆₆N₄O₂₀
SMILES

CC[C@@]12C=CCN3CC[C@](C4=C(N5C)C=C(OC)C([C@@](CC6([H])C=C(CN(C7)C6)CC)(C(OC)=O)C8=C7C9=C(N8)C=CC=C9)=C4)([C@@]5([C@](O)([C@@H]2OC(C)=O)C(OC)=O)[H])[C@]13[H].O=C([C@@H]([C@H](C(O)=O)O)O)O.O=C([C@@H]([C@H](C(O)=O)O)O)O
Synonyms

KW-2307 solution; Nor-5'-anhydrovinblastine ditartrate solution
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Ngan VK, et al. Mechanism of mitotic block and inhibition of cell proliferation by the semisynthetic Vinca alkaloids vinorelbine and its newer derivative vinflunine. Mol Pharmacol. 2001 Jul;60(1):225-32. [Content Brief]

[2]. Liu XM, et al. Unique induction of p21(WAF1/CIP1)expression by vinorelbine in androgen-independent prostate cancer cells. Br J Cancer. 2003 Oct 20;89(8):1566-73. [Content Brief]

[3]. Poirier VJ, et al. Toxicity, dosage, and efficacy of vinorelbine (Navelbine) in dogs with spontaneous neoplasia. J Vet Intern Med. 2004 Jul-Aug;18(4):536-9. [Content Brief]

[4]. Pierro JA, et al. Phase I clinical trial of vinorelbine in tumor-bearing cats. J Vet Intern Med. 2013 Jul-Aug;27(4):943-8. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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