WRN inhibitor 19
WRN inhibitor 19 (Compound 40) is a WRN helicase inhibitor (IC50: 3.7 nM). WRN inhibitor 19 exhibits selective antiproliferative activity in WRN-dependent cancer cells. WRN inhibitor 19 inhibits WRN helicase function by competitively binding to the ATP site and induces DNA damage and cell cycle arrest. WRN inhibitor 19 can be used in the study of WRN-dependent cancers.
For research use only. We do not sell to patients.
- Formula: C40H52F4N6O6
- Molecular Weight:788.87
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Helicase |
Chemical Information
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Molecular Weight 788.87
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Formula C40H52F4N6O6
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SMILES
CN(C([C@H](NC([C@@H]1CN(CC[C@@H]1NC(CCN2C(NC3=C2C=CC(CC(C)(O)C)=C3)=O)=O)C(CC4=CC=C(C=C4F)C(F)(F)F)=O)=O)CC5CCCCC5)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
WRN inhibitor 19 Related Classifications
HY-176727 Related Classifications
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