β-Interleukin I (163-171), human
β-Interleukin I (163-171), human, an immunostimulatory fragment of human IL-1β peptide, is a T cell activator. β-Interleukin I (163-171), human is not an IL-1R-binding domain of IL-1β. β-Interleukin I (163-171), human is a potent adjuvant that enhances the immune response in a variety of exptl. situations.
For research use only. We do not sell to patients.
- CAS No.: 106021-96-9
- Formula: C39H64N12O19
- Molecular Weight:1004.99
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
β-Interleukin I (163-171), human (12.5-400 μg/mL, 72 h) stimulates mouse thymocyte proliferation[6].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
β-Interleukin I (163-171), human (1 μmole/kg, i.v.) together with the T-dependent antigen SRBC increases the primary immune response against the antigen[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 106021-96-9
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Molecular Weight 1004.99
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Formula C39H64N12O19
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Sequence Shortening
VQGEESNDK
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Nencioni L, et al. In vivo immunostimulating activity of the 163-171 peptide of human IL-1 beta. J Immunol. 1987 Aug 1;139(3):800-4. [Content Brief]
[2]. Forni G, et al. Ability of a nonapeptide of the human IL-1 beta to recruit anti-tumor reactivity in recipient mice. J Immunol. 1989 Jan 15;142(2):712-8. [Content Brief]
[3]. Boraschi D, , et al. In vivo stimulation and restoration of the immune response by the noninflammatory fragment 163-171 of human interleukin 1 beta. J Exp Med. 1988 Aug 1;168(2):675-86. [Content Brief]
[5]. Boraschi D, et al. Binding and internalization of the 163-171 fragment of human IL-1 beta. Cytokine. 1992 May;4(3):201-4. [Content Brief]
[6]. Bajpai K, et al. Immunomodulating activity of analogs of noninflammatory fragment 163-171 of human interleukin-1beta. Immunopharmacology. 1998 Jan;38(3):237-45. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
β-Interleukin I (163-171), human Related Classifications
HY-113893 Related Classifications
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