1-Dehydro-[10]-gingerdione
1-Dehydro-[10]-gingerdione directly inhibits IKKβ activity by targeting the activation loop of IKKβ, thus disrupting IKKβ-catalysed IκBα phosphorylation in macrophages stimulated with agonists. 1-Dehydro-[10]-gingerdione inhibits LPS (HY-D1056)-induced NF-κB transcriptional activity. 1-Dehydro-[10]-gingerdione has the potential for NF-κB-associated inflammation and autoimmune disorders research.
For research use only. We do not sell to patients.
- CAS No.: 136826-50-1
- Formula: C21H30O4
- Molecular Weight:346.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
![1-Dehydro-[10]-gingerdione Chemical Structure](https://file.medchemexpress.com/product_pic/hy-n10768.gif "Click to View 1-Dehydro-[10]-gingerdione Chemical Structure")
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 136826-50-1
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Molecular Weight 346.46
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Formula C21H30O4
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SMILES
O=C(CC(CCCCCCCCC)=O)/C=C/C1=CC=C(C(OC)=C1)O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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