1. GPCR/G Protein
    Neuronal Signaling
  2. 5-HT Receptor
  3. 2-Methyl-5-HT hydrochloride

2-Methyl-5-HT hydrochloride (Synonyms: 2-Methyl-5-hydroxytryptamine hydrochloride; 2-Methylserotonin hydrochloride; 2-Me-HT hydrochloride)

Cat. No.: HY-19358A
Handling Instructions

2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine hydrochloride) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT hydrochloride is shown to display anti-depressive-like effects.

For research use only. We do not sell to patients.

2-Methyl-5-HT hydrochloride Chemical Structure

2-Methyl-5-HT hydrochloride Chemical Structure

CAS No. : 845861-49-6

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Description

2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine hydrochloride) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT hydrochloride is shown to display anti-depressive-like effects[1].

IC50 & Target

5-HT3 Receptor

 

In Vivo

2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine hydrochloride) (i.p.; 3 mg/kg; 45 minutes) significantly decreases time of immobility as compared to controls thus showing anti-depressive-like effects[1].

Animal Model: Male Sprague-Dawley rats[1]
Dosage: 3 mg/kg
Administration: I.p.; 45 minutes
Result: Significantly decreased time of immobility thus showing anti-depressive-like effects.
Molecular Weight

226.70

Formula

C₁₁H₁₅ClN₂O

CAS No.

845861-49-6

SMILES

OC1=CC2=C(NC(C)=C2CCN)C=C1.[H]Cl

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

2-Methyl-5-HT2-Methyl-5-hydroxytryptamine2-Methylserotonin2-Me-HT5-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorInhibitorinhibitorinhibit

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2-Methyl-5-HT hydrochloride
Cat. No.:
HY-19358A
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