2-Methyl-5-HT hydrochloride
2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine hydrochloride) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT hydrochloride is shown to display anti-depressive-like effects.
For research use only. We do not sell to patients.
- CAS No.: 845861-49-6
- Formula: C11H15ClN2O
- Molecular Weight:226.70
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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5-HT3 Receptor |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Sprague-Dawley rats[1]
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Dosage:3 mg/kg
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Administration:I.p.; 45 minutes
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Result:Significantly decreased time of immobility thus showing anti-depressive-like effects.
Chemical Information
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CAS No. 845861-49-6
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Molecular Weight 226.70
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Formula C11H15ClN2O
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SMILES
OC1=CC2=C(NC(C)=C2CCN)C=C1.[H]Cl
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Synonyms
2-Methyl-5-hydroxytryptamine hydrochloride; 2-Methylserotonin hydrochloride; 2-Me-HT hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Sumaya IC, et al. Differential effects of a short-term high-fat diet in an animal model of depression in rats treated with the 5-HT3 receptor antagonist, ondansetron, the 5-HT3 receptor agonist, 2-methyl-5-HT, and the SSRI, fluoxetine. Pharmacol Biochem Behav. 2016 May;144:78-84. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
2-Methyl-5-HT hydrochloride Related Classifications
HY-19358A Related Classifications
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