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Cat. No.: HY-125801R

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3-Oxo-5β-cholanoic acid (Standard)

Name: 3-Oxo-5β-cholanoic acid (Standard)
Brand: MedChemExpress
SKU: HY-125801R
Price: 80.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: Dehydrolithocholic acid (Standard); 3-oxoLCA (Standard))

3-Oxo-5β-cholanoic acid (Standard) is the analytical standard of 3-Oxo-5β-cholanoic acid. This product is intended for research and analytical applications. 3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid), a bile acid metabolite, inhibits the diferentiation of TH17 cells by directly binding to the key transcription factor RORγt (Kd=1.13 μM)[1].

For research use only. We do not sell to patients.

Purity: 98%
CAS No.: 1553-56-6
Formula: C₂₄H₃₈O₃
Molecular Weight:374.56

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

3-Oxo-5β-cholanoic acid (Standard) Chemical Structure

CAS No.: 1553-56-6

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 1553-56-6
Molecular Weight 374.56
Formula C₂₄H₃₈O₃
SMILES

C[C@H](CCC(O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])CC[C@]4([H])CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O
Synonyms

Dehydrolithocholic acid (Standard); 3-oxoLCA (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Hang S, et al. Bile acid metabolites control TH17 and Treg cell differentiation. Nature. 2019 Dec;576(7785):143-148. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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3-Oxo-5β-cholanoic acid (Standard)

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3-Oxo-5β-cholanoic acid (Standard)