1553-56-6
Chemical Structure
3-Oxo-5β-cholanoic acid
Synonym(s): Dehydrolithocholic acid; 3-oxoLCA
- CAS No.: 1553-56-6
- Formula:C24H38O3
- Molecular Weight:374.56
IUPAC Name: (R)-4-((5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
InChIKey: KIQFUORWRVZTHT-OPTMKGCMSA-N
SMILES: C[C@H](CCC(O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])CC[C@]4([H])CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O
Biological Activity: 3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid), a bile acid metabolite, inhibits the diferentiation of TH17 cells by directly binding to the key transcription factor RORγt (Kd=1.13 μM)[1].
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3-Oxo-5β-cholanoic acid | 99.62% | 3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid), a bile acid metabolite, inhibits the diferentiation of TH17 cells by directly binding to the key transcription factor RORγt (Kd=1.13 μM). | ||||||||||||||||||||
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3-Oxo-5β-cholanoic acid (Standard) | ≥98% | 3-Oxo-5β-cholanoic acid (Standard) is the analytical standard of 3-Oxo-5β-cholanoic acid. This product is intended for research and analytical applications. 3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid), a bile acid metabolite, inhibits the diferentiation of TH17 cells by directly binding to the key transcription factor RORγt (Kd=1.13 μM). | ||||||||||||||||||||
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3-Oxo-5β-cholanoic acid-d4 | 3-Oxo-5β-cholanoic acid-d4 (Dehydrolithocholic acid-d4) is the deuterium labeled 3-Oxo-5β-cholanoic acid (HY-125801). 3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid), a bile acid metabolite, inhibits the diferentiation of TH17 cells by directly binding to the key transcription factor RORγt (Kd=1.13 μM). | |||||||||||||||||||||
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