3-Sulfo-taurocholic Acid Disodium Salt  (Synonyms: 3-Sulfocholyl Taurine; TCA3S)

3-Sulfo-taurocholic Acid Disodium Salt (3-Sulfocholyl Taurine; TCA3S) is a metabolite of the conjugated bile acid taurocholic acid. Plasma levels of 3-Sulfo-taurocholic Acid Disodium Salt are elevated in wild-type and Sortilin 1 (Sort1) knockout mice at 6 hours following bile duct ligation (BDL) and are further elevated in Sort1 knockout mice at 24 hours post-BDL.

3-Sulfo-taurocholic Acid Disodium Salt is a metabolite of the conjugated bile acid taurocholic acid.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

639.73

C₂₆H₄₃NNa₂O₁₀S₂

71781-33-4

Solid

White to off-white

O=C(NCCS(=O)(O[Na])=O)CC[C@@H](C)[C@](CC1)([H])[C@]2(C)[C@]1([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](OS(=O)(O[Na])=O)CC[C@]4(C)[C@@]3([H])C[C@@H]2O

Room temperature in continental US; may vary elsewhere.

• [1]. Li, et al. Sortilin 1 loss-of-function protects against cholestatic liver injury by attenuating hepatic bile acid accumulation in bile duct ligated mice. Toxicol. Sci. 161(1), 34-47 (2018).