4-CPPC
Based on 1 Customer Validation
4-CPPC is a potent, reversible and selective MIF-2 inhibitor with Ki values of 431, 33 µM for MIF-1, MIF-2, respectively.
For research use only. We do not sell to patients.
- Purity: 98.20%
- CAS No.: 29553-70-6
- Formula: C14H9NO6
- Molecular Weight:287.22
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Ki: 431 µM (MIF-1); 33 µM (MIF-2)[1]
Chemical Information
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CAS No. 29553-70-6
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Appearance Solid
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Molecular Weight 287.22
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Formula C14H9NO6
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Color White to off-white
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SMILES
O=C(C1=NC=C(C(O)=O)C(C2=CC=CC(C(O)=O)=C2)=C1)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (348.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4817 mL | 17.4083 mL | 34.8165 mL | 87.0413 mL |
| 5 mM | 0.6963 mL | 3.4817 mL | 6.9633 mL | 17.4083 mL | |
| 10 mM | 0.3482 mL | 1.7408 mL | 3.4817 mL | 8.7041 mL | |
| 15 mM | 0.2321 mL | 1.1606 mL | 2.3211 mL | 5.8028 mL | |
| 20 mM | 0.1741 mL | 0.8704 mL | 1.7408 mL | 4.3521 mL | |
| 25 mM | 0.1393 mL | 0.6963 mL | 1.3927 mL | 3.4817 mL | |
| 30 mM | 0.1161 mL | 0.5803 mL | 1.1606 mL | 2.9014 mL | |
| 40 mM | 0.0870 mL | 0.4352 mL | 0.8704 mL | 2.1760 mL | |
| 50 mM | 0.0696 mL | 0.3482 mL | 0.6963 mL | 1.7408 mL | |
| 60 mM | 0.0580 mL | 0.2901 mL | 0.5803 mL | 1.4507 mL | |
| 80 mM | 0.0435 mL | 0.2176 mL | 0.4352 mL | 1.0880 mL | |
| 100 mM | 0.0348 mL | 0.1741 mL | 0.3482 mL | 0.8704 mL |