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Cat. No.: HY-184921

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5-HT2A receptor agonist-16

5-HT2A receptor agonist-16 is a 5-HT2A receptor agonist (pEC₅₀ ≥ 6), which is used in studies related to depression, anxiety disorders and headaches.

For research use only. We do not sell to patients.

CAS No.: 3122122-89-5
Formula: C₁₄H₁₅NS
Molecular Weight:229.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

5-HT2A receptor agonist-16 Chemical Structure

CAS No.: 3122122-89-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
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Biological Activity

Description

5-HT2A receptor agonist-16 is a 5-HT2A receptor agonist (pEC₅₀ ≥ 6), which is used in studies related to depression, anxiety disorders and headaches^[1].

IC₅₀ & Target

^[1]

5-HT_2A Receptor

All 5-HT Receptor Isoforms :

In Vitro

5-HT2A receptor agonist-16 (compound I-2) acts as an agonist at human 5-HT2A receptors with a pEC₅₀ of ≥ 6^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3122122-89-5
Molecular Weight 229.34
Formula C₁₄H₁₅NS
SMILES

N[C@H]1CCC(C2=CC=CC3=C2SC=C3)=CC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Sabnis RW, et al. Novel 5,6-Bicyclic Compounds as 5‑HT2A Receptor Agonists for Treating Depression, Anxiety, Substance Abuse, and Headaches. ACS medicinal chemistry letters. 2026 Jul 09;17(7):1451-1452. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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