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Cat. No.: HY-184052

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5-HT4R agonist-3

5-HT4R agonist-3 is a 5-HT4R agonist with an EC₅₀ of 22 nM. 5-HT4R agonist-3 selectively modulates 5-HT4R and induces pro-cognitive activity. 5-HT4R agonist-3 can be used in research related to Alzheimer's disease.

For research use only. We do not sell to patients.

CAS No.: 1809612-31-4
Formula: C₂₁H₃₀N₄O₂
Molecular Weight:370.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

5-HT4R agonist-3 Chemical Structure

CAS No.: 1809612-31-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
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Biological Activity

Description

IC₅₀ & Target^[1]

5-HT₄ Receptor

22 nM (EC₅₀)

All 5-HT Receptor Isoforms :

In Vitro

5-HT4R agonist-3 (compound 96) is a 5-HT4R agonist with an EC₅₀ of 22 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

5-HT4R agonist-3 (compound 96) exhibits pro-cognitive efficacy in novel object recognition and radial arm maze tests in rats^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1809612-31-4
Molecular Weight 370.49
Formula C₂₁H₃₀N₄O₂
SMILES

O=C(C1=C2N(C=CC=C2)C(C(C)C)=N1)NC[C@@H]3[C@]4([H])[C@@]3([H])CN(C4)CCCOC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Vanda D, et al. Imidazopyridine-based selective and multifunctional ligands of biological targets associated with psychiatric and neurodegenerative diseases. European journal of medicinal chemistry. 2019 Nov 01;181:111569. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References

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5-HT4R agonist-3

All 5-HT Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

5-HT4R agonist-3 Related Classifications

HY-184052 Related Classifications