5-Iodo-A-85380 dihydrochloride
Based on 1 Customer Validation
5-Iodo-A-85380 dihydrochloride is a selective ligand of nAChR. 5-Iodo-A-85380 dihydrochloride binds to α4β2 nAChRs in rat and human brain with Kds of 12 and 14 pM,respectively.
For research use only. We do not sell to patients.
- Purity : 98.97%
- CAS No.: 1217837-17-6
- Formula: C9H13Cl2IN2O
- Molecular Weight:363.02
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
Chemical Information
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CAS No. 1217837-17-6
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Appearance Solid
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Molecular Weight 363.02
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Formula C9H13Cl2IN2O
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Color White to off-white
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SMILES
IC1=CC(OC[C@@H]2CCN2)=CN=C1.[H]Cl.[H]Cl
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Synonyms
5-I A-85380 dihydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (137.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7547 mL | 13.7733 mL | 27.5467 mL | 68.8667 mL |
| 5 mM | 0.5509 mL | 2.7547 mL | 5.5093 mL | 13.7733 mL | |
| 10 mM | 0.2755 mL | 1.3773 mL | 2.7547 mL | 6.8867 mL | |
| 15 mM | 0.1836 mL | 0.9182 mL | 1.8364 mL | 4.5911 mL | |
| 20 mM | 0.1377 mL | 0.6887 mL | 1.3773 mL | 3.4433 mL | |
| 25 mM | 0.1102 mL | 0.5509 mL | 1.1019 mL | 2.7547 mL | |
| 30 mM | 0.0918 mL | 0.4591 mL | 0.9182 mL | 2.2956 mL | |
| 40 mM | 0.0689 mL | 0.3443 mL | 0.6887 mL | 1.7217 mL | |
| 50 mM | 0.0551 mL | 0.2755 mL | 0.5509 mL | 1.3773 mL | |
| 60 mM | 0.0459 mL | 0.2296 mL | 0.4591 mL | 1.1478 mL | |
| 80 mM | 0.0344 mL | 0.1722 mL | 0.3443 mL | 0.8608 mL | |
| 100 mM | 0.0275 mL | 0.1377 mL | 0.2755 mL | 0.6887 mL |
5-Iodo-A-85380 dihydrochloride Related Classifications
HY-107686 Related Classifications
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