7-Iodo-7-deaza-2'-deoxyguanosine
Based on 1 Customer Validation
7-Iodo-7-deaza-2'-deoxyguanosine (7-Deaza-7-Iodo-2'-deoxyguanosine) is a modified deoxyguanosine nucleoside. 7-Iodo-7-deaza-2'-deoxyguanosine is used in DNA synthesis and sequencing reactions.
For research use only. We do not sell to patients.
- Purity : 99.84%
- CAS No.: 172163-62-1
- Formula: C11H13IN4O4
- Molecular Weight:392.15
-
Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
All DNA/RNA Synthesis Isoforms
More
Biological Activity
Description
In Vitro
7-Iodo-7-deaza-2'-deoxyguanosine is used in DNA synthesis and sequencing reactions[1][2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 172163-62-1
-
Appearance Solid
-
Molecular Weight 392.15
-
Formula C11H13IN4O4
-
Color Off-white to light brown
-
SMILES
OC[C@H]1O[C@@H](N2C(N=C(N)NC3=O)=C3C(I)=C2)C[C@@H]1O
-
Synonyms
7-Deaza-7-Iodo-2'-deoxyguanosine
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 125 mg/mL (318.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (274 KB)
-
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
-
Handling Instructions (2659 KB)
References
[1]. Ronald Graham, et al. Nucleotide cleavable linkers and uses thereof. WO2020146397A1.
[2]. Sýkorová V, et al. Polymerase Synthesis of DNA Containing Iodinated Pyrimidine or 7-Deazapurine Nucleobases and Their Post-synthetic Modifications through the Suzuki-Miyaura Cross-Coupling Reactions. Chembiochem. 2022;23(3):e202100608. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5500 mL | 12.7502 mL | 25.5004 mL | 63.7511 mL |
| 5 mM | 0.5100 mL | 2.5500 mL | 5.1001 mL | 12.7502 mL | |
| 10 mM | 0.2550 mL | 1.2750 mL | 2.5500 mL | 6.3751 mL | |
| 15 mM | 0.1700 mL | 0.8500 mL | 1.7000 mL | 4.2501 mL | |
| 20 mM | 0.1275 mL | 0.6375 mL | 1.2750 mL | 3.1876 mL | |
| 25 mM | 0.1020 mL | 0.5100 mL | 1.0200 mL | 2.5500 mL | |
| 30 mM | 0.0850 mL | 0.4250 mL | 0.8500 mL | 2.1250 mL | |
| 40 mM | 0.0638 mL | 0.3188 mL | 0.6375 mL | 1.5938 mL | |
| 50 mM | 0.0510 mL | 0.2550 mL | 0.5100 mL | 1.2750 mL | |
| 60 mM | 0.0425 mL | 0.2125 mL | 0.4250 mL | 1.0625 mL | |
| 80 mM | 0.0319 mL | 0.1594 mL | 0.3188 mL | 0.7969 mL | |
| 100 mM | 0.0255 mL | 0.1275 mL | 0.2550 mL | 0.6375 mL |
7-Iodo-7-deaza-2'-deoxyguanosine Related Classifications
HY-W048492 Related Classifications
Powered by Bioz
Keywords
- 7-Iodo-7-deaza-2'-deoxyguanosine
- 172163-62-1
- 7-Deaza-7-Iodo-2'-deoxyguanosine
- DNA/RNA Synthesis
- Nucleoside Antimetabolite/Analog
- Suzuki-Miyaura cross-coupling
- DNA intercalator
- DNA polymerase
- sequencing by synthesis
- DNA duplexes
- double-stranded DNA
- primer extension
- arylboronic acids
- single-stranded oligonucleotides
- PCR amplification
- Inhibitor
- inhibitor
- inhibit