9-(β-D-Xylofuranosyl)adenine
Based on 1 Customer Validation
9-(β-D-Xylofuranosyl)adenine is an adenosine analogue. 9-(β-D-Xylofuranosyl)adenine shows antitumor and antiviral activity.
For research use only. We do not sell to patients.
- Purity : 99.76%
- CAS No.: 524-69-6
- Formula: C10H13N5O4
- Molecular Weight:267.24
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
IC50 & Target
[2]|
HSV-1 |
In Vitro
Chemical Information
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CAS No. 524-69-6
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Appearance Solid
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Molecular Weight 267.24
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Formula C10H13N5O4
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Color White to off-white
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SMILES
OC[C@@H]1[C@H](O)[C@@H](O)[C@H](N2C(N=CN=C3N)=C3N=C2)O1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 125 mg/mL (467.74 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
[1]. Gosselin G, et al. Systematic synthesis and biological evaluation of alpha- and beta-D-xylofuranosyl nucleosides of the five naturally occurring bases in nucleic acids and related analogues. J Med Chem. 1986 Feb;29(2):203-13. [Content Brief]
[2]. Shobukhov VM, et al. [Comparative study of antiherpetic effect of 9-beta-D-xylofuranosyl- adenine and 9-beta-D-arabinofuranosyladenine and their inhibition of defective herpes simplex type 1 virus in a cell culture]. Vopr Virusol. 1989 Nov-Dec;34(6):741-4. Russian. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7420 mL | 18.7098 mL | 37.4195 mL | 93.5489 mL |
| 5 mM | 0.7484 mL | 3.7420 mL | 7.4839 mL | 18.7098 mL | |
| 10 mM | 0.3742 mL | 1.8710 mL | 3.7420 mL | 9.3549 mL | |
| 15 mM | 0.2495 mL | 1.2473 mL | 2.4946 mL | 6.2366 mL | |
| 20 mM | 0.1871 mL | 0.9355 mL | 1.8710 mL | 4.6774 mL | |
| 25 mM | 0.1497 mL | 0.7484 mL | 1.4968 mL | 3.7420 mL | |
| 30 mM | 0.1247 mL | 0.6237 mL | 1.2473 mL | 3.1183 mL | |
| 40 mM | 0.0935 mL | 0.4677 mL | 0.9355 mL | 2.3387 mL | |
| 50 mM | 0.0748 mL | 0.3742 mL | 0.7484 mL | 1.8710 mL | |
| 60 mM | 0.0624 mL | 0.3118 mL | 0.6237 mL | 1.5591 mL | |
| 80 mM | 0.0468 mL | 0.2339 mL | 0.4677 mL | 1.1694 mL | |
| 100 mM | 0.0374 mL | 0.1871 mL | 0.3742 mL | 0.9355 mL |