SM-6586

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SM-6586 is a calcium channel antagonist and inhibitor of Na⁺/H⁺ and Na⁺/Ca²⁺ exchange transport, potentially for the treatment of cerebrovasular diseases and hypertension.

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SM-6586 화학구조

CAS No. : 103898-38-0

사이즈	재고	수량
1 mg	견적 받기 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
5 mg	견적 받기 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
10 mg	견적 받기
50 mg	견적 받기

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* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

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N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

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고객리뷰

제품 설명	SM-6586 is a calcium channel antagonist and inhibitor of Na⁺/H⁺ and Na⁺/Ca²⁺ exchange transport, potentially for the treatment of cerebrovasular diseases and hypertension.
In Vivo	In SM-6586-treated spontaneously hypertensive rats, the survival rate after bilateral common carotid artery ligation is higher, the brain water content is lower, and the ATP level is higher and lactate level. In focal ischemia models, the SM-treated group shows a reduction of T1 relaxation time. The brain water content is significantly decreased in the SM-treated group^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
분자량	489.52
화학식	C₂₆H₂₇N₅O₅
CAS No.	103898-38-0
SMILES	O=C(C1=C(C)NC(C)=C(C2=NC(CN(C)CC3=CC=CC=C3)=NO2)C1C4=CC=CC([N+]([O-])=O)=C4)OC
선적	Room temperature in continental US; may vary elsewhere.
보관	Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서	Data Sheet (271 KB) Handling Instructions (2659 KB)
References	[1]. Kashiwagi F, et al. Effect of a new calcium antagonist (SM-6586) on experimental cerebral ischemia. Acta Neurochir Suppl (Wien). 1994;60:289-92. [Content Brief]

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Cardiovascular Disease

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SM-6586103898-38-0SM6586SM 6586Calcium ChannelNa+/Ca2+ ExchangerCa2+ channelsCa channelsInhibitorinhibitorinhibit

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SM-6586

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