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Checkpoint Kinase (Chk) Related Products (43)
Related Products (43)
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Prexasertib (Standard)
0 ImagesCat. No.: HY-18174RCAS No.: 1234015-52-1Synonyms: LY2606368 (Standard)Prexasertib (Standard) is the analytical standard of Prexasertib (HY-18174). This product is intended for research and analytical applications. Prexasertib (LY2606368) is a selective, ATP-competitive second-generation checkpoint Kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of <1 nM. Prexasertib inhibits CHK2 (IC50=8 nM) and RSK1 (IC50=9 nM). Prexasertib causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib shows potent anti-tumor activity.
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AZD-7762 hydrochloride (Standard)
0 ImagesCat. No.: HY-10992ARCAS No.: 1246094-78-9AZD-7762 hydrochloride (Standard) is the analytical standard of AZD-7762 (hydrochloride) (HY-10992A). This product is intended for research and analytical applications. AZD-7762 hydrochloride is a potent ATP-competitive checkpoint Kinase (Chk) inhibitor in with an IC50 of 5 nM for Chk1.
