Cytochrome P450 Activator

Cilobamine is an orally active antidepressant and a dopamine/norepinephrine reuptake inhibitor. Cilobamine increases the levels of Aniline hydroxylase and cytochrome P-450 in rat liver. Cilobamine promotes hypertrophy of the smooth endoplasmic reticulum in rat liver hepatocytes, increases relative liver weight and recoverable microsomal protein. Cilobamine produces stimulant and anxiogenic effects, and does not inhibit monoamine oxidase. Cilobamine can be used in the research of depression.

Aceanthrenequinone is a polycyclic aromatic hydrocarbon quinone organic compound that belongs to the category of free radical photoinitiators. Aceanthrenequinone serves as an intermediate for dyes and pigments, and also acts as a substrate for organic synthesis and polymer materials. Aceanthrenequinone activates the Aryl Hydrocarbon Receptor pathway, induces the expression of CYP1A protein in the vascular system of zebrafish embryos, and causes the death of embryos at 120 hpf. Aceanthrenequinone is applicable to research related to industrial or biomedical applications.

5-trans-PGE2 (Standard) is the analytical standard of 5-trans-PGE2. This product is intended for research and analytical applications. 5-trans-PGE2 (5-trans Prostaglandin E2) is the active isomer of PGE2 and a potent activator of aromatase. Supplements the process of paracrine signaling between epithelial cells (expressing high levels of PGE2) and surrounding stromal cells (expressing high levels of aromatase). This process is involved in the growth and development of breast cancer.