2. Signaling Pathways
  3. GPCR/G Protein
  4. GPR84
  5. GPR84 Activator

GPR84 Activator

GPR84 Activator (1):

Cat. No. Product Name Effect Purity
  • HY-182723
    PSB-16671
    		Activator
    PSB-16671 is an allosteric agonist of GPR84. PSB-16671 recruits β-arrestins and couples to Gi, enhances the Gi activation potency of orthosteric agonists, and exerts a synergistic effect with orthosteric agonists. PSB-16671 promotes G protein activation and partial chemotaxis independent of GPR84 in mouse neutrophils, maintains the phagocytic function of macrophages against cancer cells without inducing receptor desensitization. PSB-16671 can be used in cancer-related research.