- Signaling Pathways
- Metabolic Enzyme/Protease
- Glycosidase
Glycosidase
Glycosidase
- [1]. Wang X, et al. Metabolites extracted from microorganisms as potential inhibitors of glycosidases (α-glucosidase and α-amylase): A review. Front Microbiol. 2022 Nov 17;13:1050869.
- [2]. Ohtsubo K, et al. Glycosylation in cellular mechanisms of health and disease. Cell. 2006 Sep 8;126(5):855-67. [Content Brief]
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Glycosidase Inhibitors
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Glycosidase Substrates
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Glycosidase Related Products (682)
Related Products (682)
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Antibodies (3)
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α-Glucosidase-IN-78
0 ImagesCat. No.: HY-170588CAS No.: 3115340-49-0α-Glucosidase-IN-78 (Compound 12m) is an inhibitor for α-glucosidase with a reversible, competitive IC50 6.0 μM. α-Glucosidase-IN-78 can be used in research of diabete for its hypoglycemic property. -
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Flaccidoside III
0 ImagesCat. No.: HY-N12138CAS No.: 140400-67-5Flaccidoside III is a triterpenoid isolated from the aerial parts of N. sativa (Ranunculaceae). Flaccidoside III inhibits α-Glucosidase (IC50: 256.7 μM) and has potential antioxidant and antidiabetic activities. -
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- α-Amylase/α-Glucosidase-IN-9
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2,3-Dihydrocalodenin B
0 ImagesCat. No.: HY-N126882,3-Dihydrocalodenin B (Compound 6) is a compound that can be isolated from Knema globularia. 2,3-Dihydrocalodenin B is a potent and non-competitive inhibitor against α-glucosidase and α-amylase, with IC50 values of 1.1 and 2.6 μM, respectively. 2,3-Dihydrocalodenin B can be used for the research of diabetes. -
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3-Oxo-hop-22(29)-ene
0 ImagesCat. No.: HY-N10440CAS No.: 25615-11-63-Oxo-hop-22(29)-ene is a yeast α-glucosidase inhibitor. 3-Oxo-hop-22(29)-ene shows a moderate effect on the viability of T. cruzi and L. mexicana. 3-Oxo-hop-22(29)-ene shows marginal activity of anti-inflammatory. -
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- α-Glucosidase-IN-81
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α-Glucosidase-IN-4
0 Imagesα-Glucosidase-IN-4 is a reversible and mixed type α-glucosidase inhibitor with an IC50 of 12.98 μM, a KI of 27.02 μM, and a KIS of 13.65 μM, respectively. -
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Luteolin 5,3'-dimethyl ether
0 ImagesCat. No.: HY-N9846CAS No.: 62346-14-9Luteolin 5,3'-dimethyl ether is a flavonoid compound that exhibits strong binding to enzymes such as acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and α-Glycosidase. Luteolin 5,3'-dimethyl ether can be naturally extracted from the dried roots of Alhagi maurorum (camel thorn). The methanol extract of this plant has significant free radical scavenging ability and enzyme inhibitory potential. Luteolin 5,3'-dimethyl ether can be used in research related to neurodegenerative diseases, diabetes, and skin pigmentation-related diseases. -
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α-Amylase/α-Glucosidase-IN-19
0 ImagesCat. No.: HY-172622CAS No.: 223505-23-5α-Amylase/α-Glucosidase-IN-19 (compound 10) is a dual inhibitor of α-amylase /α-glucosidase (IC50= 170.7 μM and 60.37 μM, respectively). -
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α-Glucosidase-IN-63
0 ImagesCat. No.: HY-161522CAS No.: 2375866-82-1α-Glucosidase-IN-63 (Compound 4d) is an inhibitor of α-Glucosidase (IC50=0.44 μM). α-Glucosidase-IN-63 inhibits hCA II with an activity of Ki= 7.0 nM. α-Glucosidase-IN-63 is orally effective.. -
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- α-Glucosidase-IN-19
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6-Prenylquercetin-3-Me ether
0 ImagesCat. No.: HY-N9051CAS No.: 151649-34-26-Prenylquercetin-3-Me ether is a natural product that can be extracted from G. uralensis leaves. 6-Prenylquercetin-3-Me ether has radical scavenging activity toward DPPH. 6-Prenylquercetin-3-Me ether also has inhibitory activity against α-glucosidase. -
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α-Glucosidase-IN-12
0 ImagesCat. No.: HY-150959CAS No.: 2816072-24-7α-Glucosidase-IN-12 (compound 14) is a potent α-glucosidase inhibitor, with an IC50 of 10.20 μM. -
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ALR2/α-Glucosidase-IN-1
0 ImagesCat. No.: HY-182311ALR2/α-Glucosidase-IN-1 (Compound 4) is a competitive ALR2 inhibitor and competitive α-glucosidase inhibitor, with an IC50 of 0.250 μM against ALR2 and an IC50 of 0.561 μM against α-glucosidase. ALR2/α-Glucosidase-IN-1 binds to the active sites of ALR2 and α-glucosidase, and inhibits enzymatic activity by competing with their respective substrates. ALR2/α-Glucosidase-IN-1 can be used in diabetes-related research. -
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α-Glucosidase-IN-95
0 ImagesCat. No.: HY-175170α-Glucosidase-IN-95 (Compound 21c) is a competitive α-Glucosidase inhibitor with an IC50 of 0.44 μM. α-Glucosidase-IN-95 has a significant inhibitory potency without cytotoxicity to normal cells. α-Glucosidase-IN-95 can be used for metabolic disorders like diabetes mellitus research. -
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UCM-17017
0 ImagesCat. No.: HY-187365UCM-17017 is a tetrasubstituted cyclohexene inhibitor that inhibits the activity of senescent cell SA-β-gal with an IC50 of 0.4 μM. UCM-17017 selectively reduces the viability of senescent cancer cells, and this effect is stronger than its impact on proliferating cells. UCM-17017 binds to human serum albumin with a KD of 230 μM. UCM-17017 reduces collagen deposition and decreases the expression of the inflammatory marker Ccl2 in a mouse model of pulmonary fibrosis. UCM-17017 can be used in studies related to senescence and pulmonary fibrosis. -
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[DArg10, Aib20] TLQP-21
0 ImagesCat. No.: HY-P1345C[DArg10, Aib20] TLQP-21 is a functional antagonist of the complement 3a receptor (C3aR), with EC50 values of 854 nM, 1007 nM, and 1715 nM against human C3aR. [DArg10, Aib20] TLQP-21 recruits β-arrestin, activates Gi3, mediates β-arrestin-dependent receptor internalization, and does not induce calcium influx. [DArg10, Aib20] TLQP-21 inhibits the adrenergic‑induced lipolysis enhancement mediated by TLQP-21 (HY-P1345) and also inhibits the β-hexosaminidase secretion induced by C3a63-77. [DArg10, Aib20] TLQP-21 can be used in research related to asthma and inflammatory diseases. -
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Euphominoid C
0 ImagesCat. No.: HY-N21640ACAS No.: 2113766-69-9Euphominoid C is a competitive α-glucosidase inhibitor (IC50 = 52.50 μM) and a mixed-type β-glucuronidase inhibitor (IC50 = 45.87 μM). Euphominoid C exhibits reversible binding modes against both enzymes. Euphominoid C can be used for the research of diabetes. -
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7β-Hydroxybufalin
0 ImagesCat. No.: HY-N6575CAS No.: 20143-97-97β-Hydroxybufalin is a bufadienolide. 7β-Hydroxybufalin can be isolated from the venom of Bufo bufo gargarizans. 7β-Hydroxybufalin inhibits α-glucosidase and acetylcholinesterase. -
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- α-Glucosidase-IN-82
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