ALR2/α-Glucosidase-IN-1
ALR2/α-Glucosidase-IN-1 (Compound 4) is a competitive ALR2 inhibitor and competitive α-glucosidase inhibitor, with an IC50 of 0.250 μM against ALR2 and an IC50 of 0.561 μM against α-glucosidase. ALR2/α-Glucosidase-IN-1 binds to the active sites of ALR2 and α-glucosidase, and inhibits enzymatic activity by competing with their respective substrates. ALR2/α-Glucosidase-IN-1 can be used in diabetes-related research.
For research use only. We do not sell to patients.
- Formula: C19H22FN7OS
- Molecular Weight:415.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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α‑glucosidase 0.561 μM (IC50) |
ALR2 0.250 μM (IC50) |
ALR2/α-Glucosidase-IN-1 potently inhibits purified ALR2 enzyme with a competitive inhibition mode, a Ki of 0.094 μM, and an IC50 of 0.250 μM, and binds to the ALR2 active site with a -9.8 kcal/mol affinity[1].
ALR2/α-Glucosidase-IN-1 potently inhibits α-glucosidase enzyme with a competitive inhibition mode, a Ki of 0.171 μM, and an IC50 of 0.561 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 415.49
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Formula C19H22FN7OS
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SMILES
FC1=CC=C(N2CCN(C(C=C3)=NN(CCC(S4)=NN=C4NC)C3=O)CC2)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ALR2/α-Glucosidase-IN-1 Related Classifications
HY-182311 Related Classifications
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