Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11101)
Related Products (11101)
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22:0 Lyso-PC-d4
0 ImagesCat. No.: HY-144086SCAS No.: 2483831-14-522:0 Lyso-PC-d4 is the deuterium labeled 22:0 Lyso-PC.
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MCPA-d3
0 ImagesCat. No.: HY-W713900CAS No.: 2469242-78-0MCPA-d3-1 is the deuterium labeled MCPA (HY-B0859). MCPA is an orally active phenoxyacetic acid herbicide. MCPA interferes with membrane integrity, energy metabolism (decreases ATP levels), and redox balance in plant cells. MCPA increases hepatic cytochrome P-450 levels and increases aniline hydroxylase and 7-ethoxycoumarin O-deethylase activities. MCPA can be used to control broadleaf weeds.
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Ivacaftor-13C6
0 ImagesCat. No.: HY-13017S4Synonyms: VX-770-13C6Ivacaftor-13C6 (VX-770-13C6) is 13C labeled Ivacaftor. Ivacaftor (VX-770) is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC50s of 100 nM and 25 nM, respectively.
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Epoxiconazole-d4
0 ImagesCat. No.: HY-119683S1CAS No.: 2699607-18-4Epoxiconazole-d4 is the deuterium labeled Epoxiconazole (HY-119683). Epoxiconazole, a fungicide, is a demethylation inhibitor of the Ergosterol biosynthesis pathway. Epoxiconazole exhibits strong inhibitory effects on both carbendazim-resistant and phenamacril-resistant isolates, and can be used for controlling many crop diseases.
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9-Bromo-10-(2-naphthyl)anthracene-d15
0 ImagesCat. No.: HY-W106110SCAS No.: 1312598-80-39-Bromo-10-(2-naphthyl)anthracene-d15 is the deuterium labeled 9-Bromo-10-(2-naphthyl)anthracene.
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Atomoxetine-d7
0 ImagesCat. No.: HY-107370SCAS No.: 919104-07-7Synonyms: Tomoxetine-d7; (R)-Tomoxetine-d7Atomoxetine-d7 (Tomoxetine-d7) is deuterium labeled Atomoxetine. Atomoxetine (Tomoxetine) is a selective noradrenaline reuptake inhibitor with Ki values of 5, 77 and 1451 nM for norepinephrine (NE), serotonin (5-HT) and dopamine (DA) transporters, respectively. Atomoxetine (Tomoxetine) increases of DAEX and NEEX in the PFC and enhances catecholaminergic neurotransmission. Atomoxetine (Tomoxetine) is a potent Na+ channels (VGSCs) blocker. Atomoxetine (Tomoxetine) can be used for attention-deficit hyperactivity disorder (ADHD) research.
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Dorzolamide-d5
0 ImagesCat. No.: HY-B0109SCAS No.: 1227097-70-2Dorzolamide-d5 is the deuterium labeled Dorzolamide. Dorzolamide (L671152) is a potent carbonic anhydrase II inhibitor, with IC50 values of 0.18 nM and 600 nM for red blood cell CA-II and CA-I respectively. Dorzolamide possesses anti-tumor activity.
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Solabegron-d8
0 ImagesCat. No.: HY-19436SCAS No.: 1250988-09-0Synonyms: GW 427353-d8Solabegron-d8 (GW 427353-d8) is deuterium labeled Solabegron. Solabegron (GW 427353) is a selective β3-adrenergic receptor agonist, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR, with an EC50 value of 22 nM. Solabegron (GW 427353) is being developed for the treatment of overactive bladder and irritable bowel syndrome.
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Deltamethrin-d6
0 ImagesCat. No.: HY-B1971S1CAS No.: 2483831-10-1Synonyms: Decamethrin-d6Deltamethrin-d6 (Decamethrin-d6) is deuterium labeled Deltamethrin. Deltamethrin (Decamethrin) is an orally active synthetic pyrethroid insecticide. Deltamethrin induces oxidative stress and results in inflammation and apoptosis via inhibiting Nrf2/HO-1 pathway. Deltamethrin has an anticancer effect by inducing apoptosis. Deltamethrin can be used extensively in pest control.
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1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoinositol-d31 ammonium
0 Images1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoinositol-d31 (ammonium) is deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoinositol (ammonium).
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Sulfisomidin-d4
0 ImagesCat. No.: HY-W719074CAS No.: 2732915-77-2Synonyms: Sulfaisodimidine-d4Sulfisomidin-d4 (Sulfaisodimidine-d4) is deuterium labeled Sulfisomidin. Sulfisomidin (Sulfaisodimidine) is an orally active short-acting sulfonamide antibacterial. Sulfisomidin can be used for the research of lower urinary tract infections.
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Adenosine-15N
0 ImagesCat. No.: HY-W779021CAS No.: 41547-82-4Synonyms: Adenine riboside-15N; D-Adenosine-15NAdenosine-15N (Adenine riboside-15N) is 15N labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.
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4-Methoxy-N,N-dimethylaniline-d2
0 ImagesCat. No.: HY-W007102SCAS No.: 3047059-88-84-Methoxy-N,N-dimethylaniline-d2 is the deuterium labeled 4-Methoxy-N,N-dimethylaniline (HY-W007102).
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L-Histidine-13C6,15N3,d5 hydrochloride hydrate
0 ImagesCat. No.: HY-W014423S1CAS No.: 2483829-32-7Synonyms: H-His-OH-13C6,15N3,d5 hydrochloride hydrateL-Histidine-13C6,15N3,d5 hydrochloride hydrate is the deuterium, 13C-, and 15-labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable.
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TPSLP{pT}PPTR-13C6,15N4 TFA
0 ImagesCat. No.: HY-P60760S1TPSLP{pT}PPTR-13C6,15N4 TFA is the 13C- and 15N-labeled TPSLP{pT}PPTR TFA. TPSLP{pT}PPTR TFA is a tau protein fragment phosphorylated in the central region.
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3-Hydroxyfluorene-d9
0 ImagesCat. No.: HY-W6541953-Hydroxyfluorene-d9 is deuterium labeled 3-Hydroxyfluorene.
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14(S)-HDHA-d5
0 ImagesCat. No.: HY-130239SSynonyms: 14(S)-HDoHE-d514(S)-HDHA-d5 (14(S)-HDoHE-d5) is deuterium labeled 14(S)-HDHA. 14(S)-HDHA (14(S)-HDoHE) is an oxygenation product of Docosahexaenoic acid (DHA). 14(S)-HDHA is a marker reflecting activation of a Docosahexaenoic acid carbon 14-lipoxygenation pathway.
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Menaquinone Epoxide-d7
0 ImagesCat. No.: HY-132523SCAS No.: 1233937-43-3Menaquinone 4-d7 2,3-Epoxide is the deuterium labeled Menaquinone 4 2,3-Epoxide.
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CYP51-IN-25
0 ImagesCat. No.: HY-174394SCYP51-IN-25 is a orally active broad spectrum antifungal agent with the MIC80 of 0.00625-0.05 μg/mL. is a CYP51-IN-25 is a deuterated compound with antibiotic properties. CYP51-IN-25 can inhibit the fungal CYP51 enzyme, block ergosterol synthesis, and disrupt cell membrane integrity. CYP51-IN-25 can be used for research on fungal infections.
