2483829-32-7
Chemical Structure
L-Histidine-13C6,15N3,d5 hydrochloride hydrate
Synonym(s): H-His-OH-13C6,15N3,d5 hydrochloride hydrate
- CAS No.: 2483829-32-7
- Formula:13C6H7D5Cl15N3O3
- Molecular Weight:223.60
IUPAC Name: L-histidine-13C6-a,b,b,2,5-d5-15N3 hydrochloride hydrate
InChIKey: CMXXUDSWGMGYLZ-BSOGWJBHSA-N
SMILES: O[13C]([13C@]([15NH2])([2H])[13C]([2H])([2H])[13C]1=[13C]([2H])[15N]=[13C]([2H])[15NH]1)=O.Cl.O
Biological Activity: L-Histidine-13C6,15N3,d5 hydrochloride hydrate is the deuterium, 13C-, and 15-labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable[1][2][3].
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L-Histidine-13C6,15N3,d5 hydrochloride hydrate | L-Histidine-13C6,15N3,d5 hydrochloride hydrate is the deuterium, 13C-, and 15-labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable. | |||||||||||||||||||||
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- [1]. Palomba L, et al., Low levels of hydrogen peroxide and L-histidine induce DNA double-strand breakage and apoptosis. Eur J Pharmacol. 1996 Dec 27;318(1):167-73. [Content Brief]
- [2]. Kawahara M, et al., D-histidine and L-histidine attenuate zinc-induced neuronal death in GT1-7 cells. Metallomics. 2013 May;5(5):453-60. [Content Brief]
- [3]. Wade A M, et al., Antioxidant characteristics of L-histidine[J]. The Journal of Nutritional Biochemistry, 1998, 9(6): 308-315.