LPL Receptor Agonist
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SEW2871 (Standard)
0 ImagesCat. No.: HY-W008947RCAS No.: 256414-75-2SEW2871 is an orally active, potent, highly selective S1P1 (sphingosine-1-phosphate type 1 receptor) agonist, with an EC50 of 13.8 nM. SEW2871 activates ERK, Akt, and Rac signaling pathways and induces S1P1 internalization and recycling. SEW2871 reduces lymphocyte numbers in blood. SEW2871 can be used for the research of diabetes, Alzheimer’s disease, liver fibrosis, and inflammatory responses.
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AUY954
0 ImagesCat. No.: HY-119221CAS No.: 820240-77-5AUY954 is an oral active and selective sphingosine-1-phosphate receptor 1 agonist with the EC50 values of 1.2 nM, 0.9 nM >10,000 nM, 1,210 nM, >1,000 nM, and 340 nM for hS1P2, mS1P2, S1P2, S1P3, S1P4, and S1P5 receptors, respectively. AUY954 can be used for study of experimental autoimmune neuritis.
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BMS-986104 hydrochloride
0 ImagesCat. No.: HY-120633ACAS No.: 1622180-39-5BMS-986104 hydrochloride is a selective S1P1 receptor partial agonist, and can be used for research of autoimmune diseases.
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ASP-4058 (Standard)
0 ImagesCat. No.: HY-111021RCAS No.: 952565-91-2ASP-4058 (Standard) is the analytical standard of ASP-4058 (HY-111021). This product is intended for research and analytical applications. ASP-4058 is a next-generation, selective and oral bioactive agonist for Sphingosine 1-Phosphate receptors 1 and 5 (S1P1 and S1P5), ameliorates rodent experimental autoimmune encephalomyelitis with a favorable safety profile.
