Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2477)
Related Products (2477)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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Kochiae fructus extract
0 ImagesCat. No.: HY-N20344Synonyms: Kochia scoparia fruit extractKochiae fructus extract (Kochia scoparia fruit extract) is an extract of Kochia scoparia (L.) Schrad., containing a variety of bioactive components with anti-inflammatory, anti-diabetic, insecticidal, anti-allergic, antipruritic, and anti-rheumatoid arthritis activities.
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Ivermectin B1a-d2-1
0 ImagesCat. No.: HY-126937SIvermectin B1a-d2-1 is the deuterium labeled Ivermectin B1a (HY-126937). Ivermectin B1a, a derivative of Avermectin B1a (HY-15308), is a main component of Ivermectin (HY-15310). Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19.
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ELQ-650
0 ImagesCat. No.: HY-163484CAS No.: 3023710-00-8ELQ-650 is a quinolone derivative, that exhibits antimicrobial activity against several protozoan parasites, including the intraerythrocytic parasites Plasmodium and Babesia. ELQ-650 attenuates babesiosis in immunosuppressed mice.
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DNA crosslinker 6
0 ImagesCat. No.: HY-168619CAS No.: 272791-87-4DNA crosslinker 6 (compound 1) is an anti-kinetoplastid compound. DNA crosslinker 6 has a strong ability to bind AT-DNA and can inhibit the binding of AT-hook 1 to DNA (IC50=0.03 µM). In addition, DNA crosslinker 6 also has antiprotozoal activity, with an EC50 value of 0.83 µM for the inhibition of T. brucei.
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Triclabendazole-13C,d3
0 ImagesCat. No.: HY-B0621S1CAS No.: 2938916-53-9Synonyms: CGA89317-13C,d3Triclabendazole-13C,d3 is the 13C- and deuterium labeled Triclabendazole.
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Sulfalene-13C6
0 ImagesCat. No.: HY-A0130SPurity: 99.0%Synonyms: Sulfametopyrazine-13C6; AS-18908-13C6Sulfalene-13C6 is the 13C6 labeled Sulfalene. Sulfalene (Sulfametopyrazine) is an antimalarial agent. Sulfalene is also a long-acting sulfonamide antibacterial.
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Antimalarial agent 3
0 ImagesCat. No.: HY-132906CAS No.: 3033386-12-5Antimalarial agent 3 shows nanomolar antiplasmodial activity (IC50 = 0.035 μM) and has a very high selectivity index with respect to mammalian cells.
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Euphorbadienol
0 ImagesEuphorbadienol (alpha-Euphorbol), a triterpenic compound, isolated from the latex of Euphorbia resinifera. The derivatives of Euphorbadienol can be used as elicitors of disease resistance, and has antileishmanial and antitrypanosomal activity.
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Piperolactam A
0 ImagesCat. No.: HY-N2894CAS No.: 112501-42-5Piperolactam A is a natural product that can be isolated from root of Piper betle. Piperolactam A exhibits promising leishmanicidal action against wild type and drug resistant strains of Leishmania donovani.
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Dihydroflavokawin B
0 ImagesCat. No.: HY-W676872CAS No.: 3791-76-2Dihydroflavokawin B is a selective COX-1 inhibitor with an IC50 of 1.22 μM. Dihydroflavokawin B weakly inhibits COX-2 and 5-LOX. Dihydroflavokawin B inhibits promastigote forms of Leishmania panamensis and Leishmania braziliensis. Dihydroflavokawin B inhibits rabbit platelet aggregation induced by Arachidonic acid, platelet activating factor, and adenosine diphosphate. Dihydroflavokawin B exhibits in vitro anti-inflammatory activity. Dihydroflavokawin B can be used for the research of leishmaniasis.
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LN002
0 ImagesCat. No.: HY-162903CAS No.: 321372-40-1LN002 is an orally active anti-Cryptosporidium oxidase inhibitor for the study of cryptosporidiosis.
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Tritrpticin
0 ImagesCat. No.: HY-P5640CAS No.: 179264-81-4Tritrpticin is a porcine-derived antimicrobial peptide with properties such as membrane disruption and hemolysis. Tritrpticin disrupts the cell membranes of bacteria, fungi and Jurkat T cell leukemia cells and induces their death. Tritrpticin also enhances the efficacy of Metronidazole (HY-B0318) against *Trichomonas vaginalis*, reduces plasma endotoxin and inflammatory cytokine levels, restricts bacterial growth in blood and visceral tissues, decreases the mortality rate of septic shock in rats and enhances the therapeutic effect of ertapenem. Tritrpticin exhibits selective cytotoxicity against Jurkat T cell leukemia cells, while showing low toxicity to normal peripheral blood mononuclear cells and red blood cells, and can serve as a template for antimicrobial peptide design. Tritrpticin can be applied to research related to bacterial infections, fungal infections, trichomoniasis, septic shock and leukemia.
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Ornidazole-13C2,15N2
0 ImagesCat. No.: HY-B0508S1Synonyms: Ro 7-0207-13C2,15N2Ornidazole-13C2,15N2 is the 13C, 15N labeled Ornidazole. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease.
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TCMDC-125431
0 ImagesCat. No.: HY-132929CAS No.: 3015474-50-4TCMDC-125431 is a novel disruptor of the malaria parasite calcium dynamics but minimally inhibits heme crystallization.
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Secnidazole-d4
0 ImagesCat. No.: HY-B1118S2Synonyms: RP-14539-d4; PM-185184-d4Secnidazole-d4 is the deuterium labeled Secnidazole. Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis.
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Anti-Trypanosoma cruzi agent-4
0 ImagesCat. No.: HY-148323CAS No.: 10001-31-7Anti-Trypanosoma cruzi agent-4 (compound 5c) is an inhibitor of Trypanosoma cruzi. Anti-Trypanosoma cruzi agent-4 can be used for the research of infection.
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Amocarzine
0 ImagesCat. No.: HY-106492CAS No.: 36590-19-9Synonyms: CGP 6140
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Antiparasitic agent-15
0 ImagesCat. No.: HY-149079CAS No.: 3046451-91-3Antiparasitic agent-15, a pyridine-thiazolidinone, has anti-Trypanosoma cruzi and leishmanicidal activities. Antiparasitic agent-15 has IC50s of 0.9 μM and 0.64 μM against trypomastigote and amastigote forms of T. cruzi. Antiparasitic agent-15 has IC50s of 42.2 μM and 9.58 μM against trypomastigote and amastigote forms of L. amazonensis. Antiparasitic agent-15 induces parasite cell death through necrosis induction. Antiparasitic agent-15 induces morphological changes such as shortening, retraction and curvature of the parasite body and leakage of internal content with T. cruzi trypomastigotes.
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LAPTc-IN-1
0 ImagesCat. No.: HY-161299CAS No.: 930898-33-2LAPTc-IN-1 (compound 4) is a competitive inhibitor targeting acidic M17 leucinopeptidase (LAPTc) with Ki=0.27 μM. LAPTc-IN-1 is a potential antagonist of the parasite Trypanosoma cruzi.
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DL-Methionine-d
0 ImagesCat. No.: HY-N0325S1CAS No.: 67866-74-4DL-Methionine-d is the deuterium labeled DL-Methionine. DL-Methionine is an essential amino acid containing sulfur with oxidative stress defense effects. DL-Methionine can be used for animal natural feed. DL-Methionine also kills H. rostochiensis on potato plants.
