272791-87-4

DNA crosslinker 6 Chemical Structure
272791-87-4

Chemical Structure

DNA crosslinker 6

  • CAS No.: 272791-87-4
  • Formula:C19H21N7O
  • Molecular Weight:363.42

SMILES: O=C(NC1=CC=C(NC2=NCCN2)C=C1)C3=CC=C(NC4=NCCN4)C=C3

Biological Activity: DNA crosslinker 6 (compound 1) is an anti-kinetoplastid compound. DNA crosslinker 6 has a strong ability to bind AT-DNA and can inhibit the binding of AT-hook 1 to DNA (IC50=0.03 µM). In addition, DNA crosslinker 6 also has antiprotozoal activity, with an EC50 value of 0.83 µM for the inhibition of T. brucei[1].

Cat. No. Product Name Purity Description Pricing
HY-168619 		DNA crosslinker 6 DNA crosslinker 6 (compound 1) is an anti-kinetoplastid compound. DNA crosslinker 6 has a strong ability to bind AT-DNA and can inhibit the binding of AT-hook 1 to DNA (IC50=0.03 µM). In addition, DNA crosslinker 6 also has antiprotozoal activity, with an EC50 value of 0.83 µM for the inhibition of T. brucei.
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